Annotation Detail for HSPB9
Basic Information Top
| Gene Symbol: | HSPB9 ( CT51,FLJ27437 ) |
|---|---|
| Gene Full Name: | heat shock protein, alpha-crystallin-related, B9 |
| Band: | 17q21.2 |
| Quick Links | Entrez ID:94086; OMIM: 608344; Uniprot ID:HSPB9_HUMAN; ENSEMBL ID: ENSG00000197723; HGNC ID: 30589 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of HSPB9 mRNA | affects expression | 17562736 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of HSPB9 mRNA | affects binding|increases activity|increases expression | 19710929 |
| D018038 | Sodium Selenite | Sodium Selenite results in increased expression of HSPB9 mRNA | increases expression | 18175754 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 3.64 | 18653653 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 4.22 | 16434500 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 3.63 | 19483382 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 3.15 | 19176532 | |
| MESH:D019457 | Chromosome Breakage | Sodium Selenite | 5.41 | 15894690 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.59 | 18249437 | |
| MESH:D003920 | Diabetes Mellitus | Sodium Selenite | 4.19 | 16285004 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 4.17 | 16781746 15619225 10915739 12540782 12958197 11529661 19739265 19923254 16227642 2444490 10663392 19420014 16177239 10774834 19085960 18713872 16081117 12153990 16109766 11743745 17906064 11739529 19416960 12392966 17522070 14550746 15968718 17562736 11461765 19164858 14986274 12594235 11834606 16393943 11421492 19370779 14725611 16485898 18071297 11287661 12705907 | |
| MESH:D056486 | Drug-Induced Liver Injury | Sodium Selenite | 4.17 | 15131321 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D004487 | Edema | pirinixic acid | 2.96 | 12083418 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 3.25 | 19236843 20131406 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.78 | 20558911 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 3.64 | 19176532 16221962 19772884 18467677 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 3.63 | 20558911 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 8.21 | 16306350 | |
| MESH:D007333 | Insulin Resistance | Sodium Selenite | 8.21 | 14714311 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 15629191 12587719 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 1.35 | 15474484 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 11587558 19014921 16610002 19784758 12587719 19460945 16611625 12969438 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 16871587 17185352 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 1.94 | 20007298 16377806 15890375 | |
| MESH:D016393 | Lymphoma, B-Cell | Sodium Selenite | 4.59 | 14737004 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 4.16 | 16239165 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 2.29 | 19151258 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 3.29 | 16411023 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 2.12 | 17405874 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D009765 | Obesity | pirinixic acid | 1.89 | 20558911 | |
| MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
| MESH:D011471 | Prostatic Neoplasms | Sodium Selenite | 3.33 | 18760546 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.56 | 19058328 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 |
| No data |