AutismKB 2.0

Annotation Detail for SYTL3


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Basic Information Top
Gene Symbol:SYTL3 ( MGC105130,MGC118883,MGC118884,MGC118885,SLP3 )
Gene Full Name: synaptotagmin-like 3
Band: 6q25.3
Quick LinksEntrez ID:94120; OMIM: NA; Uniprot ID:SYTL3_HUMAN; ENSEMBL ID: ENSG00000164674; HGNC ID: 15587
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of SYTL3 mRNAdecreases expression 20064835
D018038 Sodium Selenite Sodium Selenite results in increased expression of SYTL3 mRNAincreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0720127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.906695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.8419183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9820146248 17474063
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1520419170
MESH:D019457 Chromosome Breakage Sodium Selenite 5.5215894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.2516285004
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 2.3815131321
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0916530937
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8720471113
MESH:D007333 Insulin Resistance Sodium Selenite 3.5714714311
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1820195826 21137059
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5717053015 20064080 18520028 6695378 18816296 20464547 18569708 20135361 20869020
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.6614737004
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5716381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3611141357
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.1317292933
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.1318760546
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5510029692 19755658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3217053015
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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