Annotation Detail for FAM189A2
Basic Information
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| Gene Symbol: | FAM189A2 ( C9orf61,MGC142243,MGC142245,RP11-548B3.1,X123 ) |
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| Gene Full Name: | family with sequence similarity 189, member A2 |
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| Band: | 9q21.12 |
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| Quick Links | Entrez ID:9413; OMIM: 607710; Uniprot ID:F1892_HUMAN; ENSEMBL ID: ENSG00000135063; HGNC ID: 24820 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C548651 |
2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester |
2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of FAM189A2 mRNA | decreases expression | 19933214
|
| D013749 |
Tetrachlorodibenzodioxin |
Tetrachlorodibenzodioxin results in decreased expression of FAM189A2 mRNA | decreases expression | 19933214
|
| C025643 |
vinclozolin |
vinclozolin affects the expression of FAM189A2 mRNA | affects expression | 19015723
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Tetrachlorodibenzodioxin |
3.59 | 15322242 11752688 14514962 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Tetrachlorodibenzodioxin |
4.12 | 16835633 |
| MESH:D000740 |
Anemia |
|
Tetrachlorodibenzodioxin |
3.39 | 11748828 |
| MESH:D001008 |
Anxiety Disorders |
|
vinclozolin |
4.00 | 19015723 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
Tetrachlorodibenzodioxin |
3.53 | 12125929 |
| MESH:D001836 |
Body Weight Changes |
|
Tetrachlorodibenzodioxin |
4.66 | 15340226 |
| MESH:D001848 |
Bone Diseases, Developmental |
|
Tetrachlorodibenzodioxin |
3.02 | 15746008 |
| MESH:D001943 |
Breast Neoplasms |
|
Tetrachlorodibenzodioxin |
1.66 | 20435547 |
| MESH:D002277 |
Carcinoma |
|
Tetrachlorodibenzodioxin |
3.16 | 16835633 |
| MESH:D006332 |
Cardiomegaly |
|
Tetrachlorodibenzodioxin |
2.58 | 18670907 18850075 16120746 |
| MESH:D018281 |
Cholangiocarcinoma |
|
Tetrachlorodibenzodioxin |
3.58 | 16835633 |
| MESH:D002972 |
Cleft Palate |
|
Tetrachlorodibenzodioxin |
2.25 | 8697196 15668235 15340226 16354765 12621046 |
| MESH:D000013 |
Congenital Abnormalities |
|
Tetrachlorodibenzodioxin |
3.48 | 14669216 17141729 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Tetrachlorodibenzodioxin |
1.27 | 10048152 20055451 15322242 |
| MESH:D003456 |
Cryptorchidism |
|
vinclozolin |
4.93 | 14966744 |
| MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
Tetrachlorodibenzodioxin |
1.74 | 17107852 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Tetrachlorodibenzodioxin |
1.62 | 20420201 |
| MESH:D004362 |
Drug Toxicity |
|
Tetrachlorodibenzodioxin |
3.09 | 11462148 |
| MESH:D004487 |
Edema |
|
Tetrachlorodibenzodioxin |
2.85 | 11000095 12711302 |
| MESH:D004489 |
Edema, Cardiac |
|
Tetrachlorodibenzodioxin |
4.77 | 18230668 15322242 16714409 |
| MESH:D004715 |
Endometriosis |
|
Tetrachlorodibenzodioxin |
3.47 | 9294722 10568697 |
| MESH:D005124 |
Eye Abnormalities |
|
Tetrachlorodibenzodioxin |
3.34 | 11564622 |
| MESH:D005313 |
Fetal Death |
|
Tetrachlorodibenzodioxin |
4.11 | 11858732 |
| MESH:D005355 |
Fibrosis |
|
Tetrachlorodibenzodioxin |
3.60 | 20067830 |
| MESH:D030342 |
Genetic Diseases, Inborn |
|
vinclozolin |
5.68 | 16973722 |
| MESH:D005832 |
Genital Diseases, Male |
|
vinclozolin |
6.17 | 16417039 |
| MESH:D006058 |
Gonadal Disorders |
|
Tetrachlorodibenzodioxin |
5.46 | 10696789 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Tetrachlorodibenzodioxin |
2.53 | 10048152 11294989 |
| MESH:D006470 |
Hemorrhage |
|
Tetrachlorodibenzodioxin |
3.82 | 11000095 |
| MESH:D006529 |
Hepatomegaly |
|
Tetrachlorodibenzodioxin |
3.54 | 15340226 16120746 12621046 |
| MESH:D006869 |
Hydronephrosis |
|
Tetrachlorodibenzodioxin |
4.91 | 15340226 8697196 18606429 16354765 16959395 |
| MESH:D006973 |
Hypertension |
|
Tetrachlorodibenzodioxin |
2.03 | 18850075 18670907 |
| MESH:D007248 |
Infertility, Male |
|
vinclozolin |
3.32 | 16467254 |
| MESH:D007249 |
Inflammation |
|
Tetrachlorodibenzodioxin |
2.04 | 12878042 12200463 |
| MESH:D007569 |
Jaw Abnormalities |
|
Tetrachlorodibenzodioxin |
3.82 | 16580747 |
| MESH:D007984 |
Leydig Cell Tumor |
|
vinclozolin |
5.47 | 16417039 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Tetrachlorodibenzodioxin |
1.25 | 12878042 |
| MESH:D008113 |
Liver Neoplasms |
|
Tetrachlorodibenzodioxin |
1.84 | 16984957 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Tetrachlorodibenzodioxin |
2.35 | 12151625 |
| MESH:D008175 |
Lung Neoplasms |
|
Tetrachlorodibenzodioxin |
1.24 | 11884234 19555203 |
| MESH:D017202 |
Myocardial Ischemia |
|
Tetrachlorodibenzodioxin |
3.38 | 12213967 |
| MESH:D009421 |
Nervous System Malformations |
|
Tetrachlorodibenzodioxin |
3.80 | 14600291 |
| MESH:D010382 |
Peliosis Hepatis |
|
Tetrachlorodibenzodioxin |
5.12 | 12520081 |
| MESH:D017119 |
Porphyria Cutanea Tarda |
|
Tetrachlorodibenzodioxin |
4.14 | 18163543 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
Tetrachlorodibenzodioxin |
12.10 | 11118676 11896295 11399792 11222880 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
vinclozolin |
12.10 | 18042343 18220299 19015723 |
| MESH:D011469 |
Prostatic Diseases |
|
vinclozolin |
5.68 | 18220299 |
| MESH:D011472 |
Prostatitis |
|
vinclozolin |
5.68 | 18629315 |
| MESH:D015619 |
Respiratory System Abnormalities |
|
Tetrachlorodibenzodioxin |
4.42 | 18990726 |
| MESH:D012878 |
Skin Neoplasms |
|
Tetrachlorodibenzodioxin |
2.21 | 16192470 |
| MESH:D013959 |
Thyroid Diseases |
|
Tetrachlorodibenzodioxin |
4.77 | 12697716 |
| MESH:D054079 |
Vascular Malformations |
|
Tetrachlorodibenzodioxin |
5.46 | 12125929 |
| MESH:D019282 |
Wasting Syndrome |
|
Tetrachlorodibenzodioxin |
5.12 | 15886252 |
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