Annotation Detail for ARHGAP12

Basic Information
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Pathway ID | Pathway Name |
---|
| Signaling by Rho GTPases |
Pathway ID | Pathway Name |
---|
P00047 | PDGF signaling pathway |
Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
---|
D000082 |
Acetaminophen |
Acetaminophen affects the expression of ARHGAP12 mRNA | affects expression | 17562736
|
D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of ARHGAP12 mRNA | affects expression | 20382639
|
D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ARHGAP12 mRNA | decreases expression | 19150397
|
C006253 |
pirinixic acid |
pirinixic acid results in decreased expression of ARHGAP12 mRNA | decreases expression | 18445702
|
Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
---|
MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.64 | 18653653 |
MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.22 | 16434500 |
MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.71 | 10982225 |
MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.39 | 18445737 |
MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.63 | 19483382 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.41 | 3084413 |
MESH:D002386 |
Cataract |
|
Acetaminophen |
2.81 | 10977129 |
MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
3.01 | 20889678 |
MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.15 | 19176532 |
MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.59 | 18249437 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.68 | 12594235 12705907 16393943 18071297 11743745 16781746 11739529 11461765 18713872 17906064 19420014 14725611 16485898 14550746 19923254 12540782 2444490 10915739 19370779 14986274 17562736 11287661 19164858 10663392 17522070 19416960 12392966 11834606 10774834 12153990 16177239 19739265 16109766 11529661 15968718 16227642 11421492 12958197 15619225 19085960 16081117 |
MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.96 | 19426721 |
MESH:D004487 |
Edema |
|
pirinixic acid |
2.96 | 12083418 |
MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.15 | 20426865 |
MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.25 | 19236843 20131406 |
MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.54 | 16983495 |
MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.78 | 20558911 |
MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.64 | 16221962 18467677 19176532 19772884 |
MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
3.06 | 16870215 |
MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.63 | 20558911 |
MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.90 | 16306350 |
MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.42 | 15629191 12587719 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.71 | 19014921 16610002 19784758 12587719 12969438 16611625 19460945 11587558 |
MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.68 | 17185352 16871587 |
MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.94 | 16377806 15890375 20007298 |
MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.22 | 19513568 |
MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.16 | 16239165 |
MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.29 | 19151258 |
MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.29 | 16411023 |
MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.12 | 17405874 |
MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.26 | 18514411 |
MESH:D009765 |
Obesity |
|
pirinixic acid |
1.89 | 20558911 |
MESH:D010146 |
Pain |
|
Acetaminophen |
2.77 | 16870215 |
MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.56 | 19058328 |
MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.50 | 10982225 |
Pathway ID |
Pathway Name |
---|
REACT:11044 |
Signaling by Rho GTPases |