AutismKB 2.0

Annotation Detail for NTN1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NTN1 ( NTN1L )
Gene Full Name: netrin 1
Band: 17p13.1
Quick LinksEntrez ID:9423; OMIM: 601614; Uniprot ID:NET1_HUMAN; ENSEMBL ID: ENSG00000065320; HGNC ID: 8029
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04360Axon guidance
Pathway IDPathway Name
Axon guidance
Pathway IDPathway Name
200074Netrin-mediated signaling
No data
Pathway IDPathway Name
500090Netrin mediated repulsion signals
500089DCC mediated attractive signaling
500088Netrin-1 signaling
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2053Colon cancer
2111Systemic infection
2237Neoplasm metastasis
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of NTN1 mRNAaffects expression 16483693
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of NTN1 mRNAaffects expression 17484886
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.4418287403
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.5416227642 3786805 15700767 18705752 15673190 16097048 16011737 10355542 15721981 16192424 16050911 16124888
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 1.8618788625
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 2.1419336974 7440962 3732212 10915739 15027814 2869522 19085960 21278145 6884620 17522070 7120509 9327722 10092053 15968718 16227642 4309450 11566570 7179309 16177239 15998439 3786805 6623471
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.7212795759 61145 12631006 16045604 15959796 17595544 19224547 16239168
MESH:D005355 Fibrosis Carbon Tetrachloride 4.2218705752
MESH:D006505 Hepatitis Carbon Tetrachloride 4.2719900420 19110552
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.4216899240
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.8515338365
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 3.0417157831 11903743 16943688 17334410 16221502 11408273 16239168 21278145 17174718
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7612445418 18006644 14724832 15818738 16033810 15338365 18705752 15925388 17976157 12649538 15876570 18210741 15650968 12546737 16011737 17698563 15057751 18205269 20821823 18339082 18420326 18277467 17766677 15362042 14716833 12632514 18395095 17714472 12609069 15730626 12445421 18251166 17640975 14620537 17944888 15931870 18317297 12898905 16027843 14512876 18263696 15370692 15959796 18412020 11481614 18279442 18481824 17805973 18166357 17869086 15893842 18395914 18429990 17761835 18156304 17823541 12389079 15996030 16015684 10355542 15052691 18472094 13678700 18376398 18187930 18472332 17565644 14716496 12958196 12586293 16097048 17922224 17525996 16136751 17900296 17721639 16116963 16248980 12667390 14748882 17631135 15123356 12632512 12666154 18054572 12741479 16192424 15673190 18418968 17708605 17557913 16638106 17481882
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1715720792 16246199 16964402 15830285 17285989
MESH:D017093 Liver Failure Carbon Tetrachloride 4.9315123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 4.2016899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 2.3619294768
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.8912014681 15583823
Pathway ID Pathway Name
REACT:18266 Axon guidance
KEGG:04360 Axon guidance
REACT:23853 Interactions of the immunoglobulin superfamily (IgSF) member proteins
REACT:22291 Phosphorylation of PLCgamma by Netrin-1
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved