Annotation Detail for MED23
Basic Information Top
| Gene Symbol: | MED23 ( ARC130,CRSP130,CRSP133,CRSP3,DKFZp434H0117,DRIP130,SUR-2,SUR2 ) |
|---|---|
| Gene Full Name: | mediator complex subunit 23 |
| Band: | 6q23.2 |
| Quick Links | Entrez ID:9439; OMIM: 605042; Uniprot ID:MED23_HUMAN; ENSEMBL ID: ENSG00000112282; HGNC ID: 2372 |
| Relate to Another Database: | SFARIGene; denovo-db |
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| Pathway ID | Pathway Name |
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| Gene Expression |
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| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of MED23 mRNA | affects expression | 17562736 |
| C065180 | fluvastatin | [zoledronic acid co-treated with fluvastatin] results in increased expression of MED23 mRNA | affects cotreatment|increases expression | 16996129 |
| C088658 | zoledronic acid | [zoledronic acid co-treated with fluvastatin] results in increased expression of MED23 mRNA | affects cotreatment|increases expression | 16996129 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D058186 | Acute Kidney Injury | zoledronic acid | 4.94 | 19715164 | |
| MESH:D000210 | Acute-Phase Reaction | zoledronic acid | 6.22 | 20200999 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001859 | Bone Neoplasms | zoledronic acid | 5.49 | 16778634 19442620 15867366 11697798 16121404 17312309 | |
| MESH:D001862 | Bone Resorption | zoledronic acid | 5.19 | 18404659 8053405 11869084 16769263 15845617 18496637 | |
| MESH:D001943 | Breast Neoplasms | zoledronic acid | 3.26 | 16096432 18695136 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | zoledronic acid | 3.66 | 19233551 | |
| MESH:D002292 | Carcinoma, Renal Cell | zoledronic acid | 4.02 | 18507039 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D003327 | Coronary Disease | fluvastatin | 5.07 | 16142594 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 11287661 16081117 11529661 11461765 14550746 18071297 11743745 11834606 19420014 16227642 17562736 19739265 10915739 16177239 11739529 19085960 16393943 12958197 16485898 14725611 17906064 15968718 19370779 16781746 12540782 19416960 15619225 16109766 19923254 17522070 19164858 11421492 18713872 14986274 12594235 12705907 12153990 10774834 10663392 12392966 2444490 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D005264 | Femoral Fractures | zoledronic acid | 6.57 | 16234978 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 9.24 | 16870215 | |
| MESH:D006930 | Hyperalgesia | zoledronic acid | 9.24 | 16769263 | |
| MESH:D006934 | Hypercalcemia | zoledronic acid | 5.53 | 19622757 18089816 | |
| MESH:D006996 | Hypocalcemia | zoledronic acid | 7.06 | 12669777 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 12587719 15629191 | |
| MESH:D015459 | Leukemia-Lymphoma, Adult T-Cell | zoledronic acid | 5.25 | 18089816 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 12587719 12969438 16611625 19460945 16610002 19014921 11587558 19784758 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 17185352 16871587 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | zoledronic acid | 3.98 | 17312309 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D008654 | Mesothelioma | zoledronic acid | 3.89 | 16675582 | |
| MESH:D009101 | Multiple Myeloma | fluvastatin | 9.21 | 16996129 | |
| MESH:D009101 | Multiple Myeloma | zoledronic acid | 9.21 | 18089719 19621390 16996129 | |
| MESH:D009362 | Neoplasm Metastasis | zoledronic acid | 3.78 | 17312309 15867366 19139120 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D010014 | Osteolysis | zoledronic acid | 6.11 | 15867366 | |
| MESH:D010024 | Osteoporosis | zoledronic acid | 4.28 | 17882678 | |
| MESH:D010146 | Pain | Acetaminophen | 8.27 | 16870215 | |
| MESH:D010146 | Pain | zoledronic acid | 8.27 | 16475674 | |
| MESH:D011471 | Prostatic Neoplasms | zoledronic acid | 4.18 | 19103299 12438248 | |
| MESH:D012512 | Sarcoma, Ewing's | zoledronic acid | 5.52 | 16121404 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 |
| Pathway ID | Pathway Name |
|---|---|
| REACT:15380 | Diabetes pathways |
| REACT:71 | Gene Expression |
| REACT:27166 | Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes |
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