AutismKB 2.0

Annotation Detail for MED26


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Basic Information Top
Gene Symbol:MED26 ( CRSP7,CRSP70 )
Gene Full Name: mediator complex subunit 26
Band: 19p13.11
Quick LinksEntrez ID:9441; OMIM: 605043; Uniprot ID:MED26_HUMAN; ENSEMBL ID: ENSG00000105085; HGNC ID: 2376
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
Gene Expression
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Pathway IDPathway Name
500652Generic Transcription Pathway
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of MED26 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 5.2610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8610977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6910774834 17562736 12705907 18713872 19739265 10663392 11421492 19420014 12958197 11739529 16177239 19164858 17906064 14550746 11834606 12540782 18071297 11529661 16081117 19923254 11287661 19370779 19085960 2444490 15968718 12153990 14725611 11743745 17522070 16485898 12392966 16393943 16227642 12594235 10915739 15619225 16109766 11461765 14986274 19416960 16781746
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.5119426721
MESH:D005756 Gastritis Acetaminophen 5.0916983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1516870215
MESH:D007674 Kidney Diseases Acetaminophen 2.4712587719 15629191
MESH:D008107 Liver Diseases Acetaminophen 1.7219784758 16610002 19014921 16611625 12969438 12587719 19460945 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.8117185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.4719513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3618514411
MESH:D010146 Pain Acetaminophen 2.8716870215
MESH:D014581 Urticaria Acetaminophen 3.6710982225
Pathway ID Pathway Name
REACT:15380 Diabetes pathways
REACT:71 Gene Expression
REACT:27166 Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes
Pharmacogenomics Knowledge Base Top
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018