Annotation Detail for AIM2
Basic Information
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| Pathway ID | Pathway Name |
|---|
| hsa04623 | Cytosolic DNA-sensing pathway |
| Desease ID | Desease Name |
|---|
| 2053 | Colon cancer |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D008727 |
Methotrexate |
AIM2 protein affects the susceptibility to Methotrexate | affects response to substance | 16217747
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Methotrexate |
5.33 | 12039119 |
| MESH:D001172 |
Arthritis, Rheumatoid |
|
Methotrexate |
3.19 | 17286800 |
| MESH:D001943 |
Breast Neoplasms |
|
Methotrexate |
3.05 | 16978400 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Methotrexate |
2.67 | 12039119 9562676 |
| MESH:D003550 |
Cystic Fibrosis |
|
Methotrexate |
4.81 | 19747007 |
| MESH:D003882 |
Dermatomyositis |
|
Methotrexate |
5.91 | 20191521 |
| MESH:D006086 |
Graft vs Host Disease |
|
Methotrexate |
6.06 | 16518429 |
| MESH:D007805 |
Language Development Disorders |
|
Methotrexate |
5.80 | 9562676 |
| MESH:D008103 |
Liver Cirrhosis |
|
Methotrexate |
3.95 | 14986274 |
| MESH:D017563 |
Lung Diseases, Interstitial |
|
Methotrexate |
6.44 | 18516814 |
| MESH:D008223 |
Lymphoma |
|
Methotrexate |
4.33 | 17352296 |
| MESH:D052016 |
Mucositis |
|
Methotrexate |
6.37 | 17488658 |
| MESH:D011565 |
Psoriasis |
|
Methotrexate |
3.57 | 17410198 |
| MESH:D051437 |
Renal Insufficiency |
|
Methotrexate |
5.62 | 17352296 |
| MESH:D013576 |
Syndactyly |
|
Methotrexate |
5.82 | 9562676 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:04623 |
Cytosolic DNA-sensing pathway |
Pharmacogenomics Knowledge Base