AutismKB 2.0

Annotation Detail for LITAF


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Basic Information Top
Gene Symbol:LITAF ( FLJ38636,MGC116698,MGC116700,MGC116701,MGC125274,MGC125275,MGC125276,PIG7,SIMPLE,TP53I7 )
Gene Full Name: lipopolysaccharide-induced TNF factor
Band: 16p13.13
Quick LinksEntrez ID:9516; OMIM: 603795; Uniprot ID:LITAF_HUMAN; ENSEMBL ID: ENSG00000189067; HGNC ID: 16841
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1726Charcot-Marie-Tooth disease
1791Neuropathy
Desease Name
CARDIOVASCULAR
QT interval
Desease Name
QT interval
Desease Name
Charcot-Marie-Tooth disease, type 1C
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of LITAF mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of LITAF mRNAaffects expression 17562736
D000535 Aluminum [Titanium co-treated with Vanadium co-treated with Aluminum] results in increased expression of LITAF mRNAaffects cotreatment|increases expression 17408380
D001374 Azacitidine Azacitidine results in decreased expression of LITAF mRNAdecreases expression 19194470
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of LITAF mRNAdecreases expression 20018196
D016572 Cyclosporine Cyclosporine results in increased expression of LITAF mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in decreased expression of LITAF mRNAdecreases expression 18042831
D004041 Dietary Fats Dietary Fats results in increased expression of LITAF mRNAincreases expression 15238619
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of LITAF mRNAincreases expression 19638242
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of LITAF mRNAincreases expression 17005392
D004610 Ellagic Acid Ellagic Acid results in increased expression of LITAF mRNAincreases expression 12002526
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LITAF mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of LITAF mRNAincreases expression 17557909
12655037
C056933 fumonisin B1 fumonisin B1 results in increased expression of LITAF mRNAincreases expression 16221962
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of LITAF mRNAincreases expression 17408380
D016685 Mitomycin LITAF protein affects the susceptibility to Mitomycinaffects response to substance 16217747
C029938 nickel sulfate nickel sulfate results in increased expression of LITAF mRNAincreases expression 16100012
D017239 Paclitaxel LITAF protein affects the susceptibility to Paclitaxelaffects response to substance 16217747
C041786 palm oil palm oil results in decreased expression of LITAF mRNAdecreases expression 18042831
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of LITAF mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of LITAF mRNAincreases expression 18445702
D020959 Polyethylene Polyethylene results in increased expression of LITAF mRNAincreases expression 17408380
C059514 resveratrol resveratrol results in increased expression of LITAF mRNAincreases expression 12002526
12569576
D012643 Selenium Selenium results in increased expression of LITAF mRNAincreases expression 19244175
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of LITAF mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LITAF mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of LITAF mRNAdecreases expression 18796159
D014025 Titanium [Titanium co-treated with Vanadium co-treated with Aluminum] results in increased expression of LITAF mRNAaffects cotreatment|increases expression 17408380
D014639 Vanadium [Titanium co-treated with Vanadium co-treated with Aluminum] results in increased expression of LITAF mRNAaffects cotreatment|increases expression 17408380
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.6814514962 15322242 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7717505938
MESH:D058186 Acute Kidney Injury resveratrol 3.7016538975
MESH:D055371 Acute Lung Injury Lipopolysaccharides 14.3911850527 18653653
MESH:D055371 Acute Lung Injury nickel sulfate 14.3911954676 16100012 19131640 12718980
MESH:D055371 Acute Lung Injury pirinixic acid 14.3918653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.7714692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 10.653712494
MESH:D000236 Adenoma Diethylnitrosamine 10.6510737359 6695378
MESH:D000236 Adenoma resveratrol 10.6515688382
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 16.2819052882 16434500 19061943 17162532 17620307 18056438
MESH:D018248 Adenoma, Liver Cell pirinixic acid 16.2816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 16.2816835633
MESH:D000544 Alzheimer Disease Aluminum 4.7217662457 10721010
MESH:D000544 Alzheimer Disease resveratrol 4.7216162502 16183991
MESH:D000686 Amyloidosis Diethylstilbestrol 4.3115469931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8011748828
MESH:D000799 Angioedema Acetaminophen 3.6710982225
MESH:D001161 Arteriosclerosis Dietary Fats 9.3415238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.3411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.0115885639
MESH:D001169 Arthritis, Experimental resveratrol 7.0117115116
MESH:D050197 Atherosclerosis resveratrol 3.1716873680 17967414
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.851440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.2519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.2512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6515746008
MESH:D001859 Bone Neoplasms Paclitaxel 4.4115867366
MESH:D002545 Brain Ischemia resveratrol 4.1117600658
MESH:D001943 Breast Neoplasms Dietary Fats 3.6720435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.6717474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 3.6717129689 15324884
MESH:D001943 Breast Neoplasms Paclitaxel 3.6716115903 16244791 11325840 16273361 18223236 18323546 18234424 15136595
MESH:D001943 Breast Neoplasms resveratrol 3.6717651959 16393696 17534123
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.6720435547
MESH:D001943 Breast Neoplasms Vanadium 3.6715565634
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6616835633
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 13.667296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 13.663084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 13.6616830150 18788625 19335982 16878318 17428255 20214788 20514400 19171122 17162532 16502159 19822196 16328049 18971187 11831363 19107877 17055752 16540662 16935385 10737359 18210153 16698587 18506893 19418558 19052882 16779866 16569478 20432363 10672840 3581430 19539802 20512989 20524982 18056438 17761372 18665156 20727157 18978308 18393292 19383236 19701751 20007298 17173139 20101231 16288022 21159647 17138121 18691550 19919837 18494052 17978847 16681979 19208518 16807293 3084413 19519916 19394651 20084675 20935162 18785209
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 13.6616924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 13.6616313753
MESH:D006528 Carcinoma, Hepatocellular resveratrol 13.6616227395 19321006
MESH:D006528 Carcinoma, Hepatocellular Vanadium 13.6616878318 16830150
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.4216675471
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.607296757
MESH:D002294 Carcinoma, Squamous Cell resveratrol 2.6716227395
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2718850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases resveratrol 3.3615458977
MESH:D002386 Cataract Acetaminophen 2.4810977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 19.877505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 19.8720889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 19.8712371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 19.872727394 21159647 17174075 7505956
MESH:D002471 Cell Transformation, Neoplastic Vanadium 19.8717174075
MESH:C537984 Charcot-Marie-Tooth disease, Type 1C marker/mechanism
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.8419052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.8416835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 18.179022650 19486331
MESH:D002779 Cholestasis Cyclosporine 18.1719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 18.1717681005 15861022 16105132 11677210 16919318 17333356 17110522
MESH:D002779 Cholestasis pirinixic acid 18.1719176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0316354765 15340226 12621046 8697196 15668235
MESH:D003092 Colitis resveratrol 9.0916474422
MESH:D003092 Colitis Selenium 9.0917936198
MESH:D003110 Colonic Neoplasms resveratrol 4.3516338953
MESH:D003110 Colonic Neoplasms Vanadium 4.3518155637
MESH:D015179 Colorectal Neoplasms Azacitidine 3.5819934284
MESH:D015179 Colorectal Neoplasms Paclitaxel 3.5818802399
MESH:D015179 Colorectal Neoplasms resveratrol 3.5816550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9117141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.6416507316
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2515322242 10048152 20055451
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.3912952375 16002989
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 6.5818759878 14531868 8156756 2524372 12868966 8970840 11906362 11298694
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 6.5816780908 11298694 16823706
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3518249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.333621924 2952479
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.6316873680
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.0820387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.0817107852
MESH:D003928 Diabetic Nephropathies resveratrol 3.8216286809
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 14.5918289764 9022650 8291058 9653073 18692083 16192314 18648102 1440618 6482804 11289319 6679447 7440962 9328219
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 14.5912594235 16227642 19370779 17906064 2444490 11834606 15619225 14986274 17562736 11461765 19420014 18071297 16393943 15968718 19923254 19085960 19164858 11743745 10663392 14725611 14550746 12958197 11421492 16177239 18713872 12705907 12540782 19416960 11529661 16081117 16485898 10915739 12392966 11739529 10774834 19739265 12153990 16109766 17522070 11287661 16781746
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 14.5919107877
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 14.5916221962
MESH:D056486 Drug-Induced Liver Injury Selenium 14.5915131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 14.5920420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9319426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6311462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3318367378
MESH:D004487 Edema pirinixic acid 10.5312083418
MESH:D004487 Edema resveratrol 10.538985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.5312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7315322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.5712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 8.5717872969
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 4.5216402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 3.3515700306 16804899
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.8710568697 9294722
MESH:D019446 Endotoxemia Lipopolysaccharides 4.2217637181 15328337 15821434
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.6817923197
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9416302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.043581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.0420426865
MESH:D004938 Esophageal Neoplasms Paclitaxel 7.0416481741
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8911564622
MESH:D005234 Fatty Liver Cyclosporine 22.9719224547
MESH:D005234 Fatty Liver Dietary Fats 22.9719551842 18296743 17967931 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 22.9721071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 22.9715345470
MESH:D005234 Fatty Liver pirinixic acid 22.9720131406 19236843
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.5516534752 16513791 15751030 16002989 16611131
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2911858732
MESH:D005334 Fever Lipopolysaccharides 3.869205823 11852909
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.856705139
MESH:D005355 Fibrosis Cyclosporine 13.7312639820 12168785
MESH:D005355 Fibrosis Dietary Fats 13.7318296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.7320067830
MESH:D005756 Gastritis Acetaminophen 3.5016983495
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.7716452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.058708960
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.887505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4210696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.2411294989 10048152
MESH:D006333 Heart Failure pirinixic acid 6.6020558911
MESH:D006333 Heart Failure Selenium 6.6017162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2515720958
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.2316366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1811000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.356705139
MESH:D006529 Hepatomegaly fumonisin B1 13.5016221962
MESH:D006529 Hepatomegaly pirinixic acid 13.5016221962 19772884 19176532 18467677
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 13.5015340226 12621046 16120746
MESH:D006561 Herpes Simplex resveratrol 4.0116876885
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8716354765 15340226 16959395 8697196 18606429
MESH:D006930 Hyperalgesia Acetaminophen 2.5716870215
MESH:D006937 Hypercholesterolemia Dietary Fats 8.7021332399
MESH:D006937 Hypercholesterolemia resveratrol 8.7017188708
MESH:D006943 Hyperglycemia pirinixic acid 3.0320558911
MESH:D006949 Hyperlipidemias Dietary Fats 8.7521332399
MESH:D006949 Hyperlipidemias resveratrol 8.7516873680
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 10.2715034207
MESH:D006965 Hyperplasia Diethylstilbestrol 10.2712960047 14722030
MESH:D006973 Hypertension Cyclosporine 4.7310903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.7318670907 18850075
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.1517488730
MESH:D007021 Hypospadias Diethylstilbestrol 10.6716002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.6716945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.4817600658
MESH:D007246 Infertility Diethylstilbestrol 4.1915036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3717937319
MESH:D007249 Inflammation Aluminum 18.8316052892
MESH:D007249 Inflammation Dietary Fats 18.8320412841
MESH:D007249 Inflammation Diethylnitrosamine 18.8318785209
MESH:D007249 Inflammation Lipopolysaccharides 18.8312878042 17255318 17237260 17963957 9205823
MESH:D007249 Inflammation resveratrol 18.8316366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 18.8312200463 12878042
MESH:D007251 Influenza, Human resveratrol 10.5016624496
MESH:D007251 Influenza, Human Selenium 10.5016624496
MESH:D007333 Insulin Resistance Dietary Fats 6.8818457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 6.8816306350
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.4717255318
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.859022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1816580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2715604871
MESH:D007674 Kidney Diseases Acetaminophen 5.4712587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 5.478314463 10903974 18776723
MESH:D007676 Kidney Failure, Chronic Selenium 3.7316518626
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 11.626582329
MESH:D007680 Kidney Neoplasms Cyclosporine 11.6212371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 11.6215003126 16762066 14681315
MESH:D007859 Learning Disorders Diethylstilbestrol 3.8917184923
MESH:D007938 Leukemia Azacitidine 3.6119148494
MESH:D007951 Leukemia, Myeloid Azacitidine 4.4719077051
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 2.9718720364 17596541
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 5.0319299654
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.4716087638
MESH:D007970 Leukopenia Lipopolysaccharides 4.5315821434
MESH:D008080 Liposarcoma Paclitaxel 4.6617353645
MESH:D008103 Liver Cirrhosis Dietary Fats 6.3218296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.3218665156 18522880 19638242 20032147 18407596
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.0915034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 3.3412878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.3415474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.3412878042
MESH:D008107 Liver Diseases Acetaminophen 3.7619784758 16611625 19460945 16610002 19014921 11587558 12969438 12587719
MESH:D008107 Liver Diseases Diethylnitrosamine 3.7617034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.0816871587 17185352
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.1521278145 20118626 18754104 21167192 12112319 19256749 19638242 21071580 19294768 9163691 20101389 20501860 19690152 19996281 18648771 19255062 18977376 19551842 20452335 19833225 19254457 2422723 15175105 19073162 20137499 18978307 12771043 19090486 19812893 2862719 18644402 19850985 19499222 21047994 19426721 16942905 20405173 20583210 20492335 15885732 10737359 20434301 19642983 19427195
MESH:D008113 Liver Neoplasms Diethylstilbestrol 17.1515890375 16712894
MESH:D008113 Liver Neoplasms Mitomycin 17.1515113037
MESH:D008113 Liver Neoplasms pirinixic acid 17.1520007298 15890375 16377806
MESH:D008113 Liver Neoplasms resveratrol 17.1519812893 20405173 19321006 19073162
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.1516984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 13.311399818 598648 3712494 6587162
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.3118308698 18164116 19004024 16267830 19519916 19539802 17854601 18079962 19126423 19009564 2563599 18775883 21159647 18253720 18282651 18544905 18093689 17942915 16842330 9362446 3124819 17174075
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.3112151625
MESH:D008114 Liver Neoplasms, Experimental Vanadium 13.3117174075
MESH:D008171 Lung Diseases Aluminum 4.5316052892
MESH:D055370 Lung Injury Lipopolysaccharides 3.8421114838
MESH:D008175 Lung Neoplasms Azacitidine 3.3921224363
MESH:D008175 Lung Neoplasms Diethylnitrosamine 3.3920970405 6695378 20512841 21163286
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.3911884234 19555203
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.9815166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.3515700306
MESH:D016393 Lymphoma, B-Cell resveratrol 4.1417088997
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 8.5214749477
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 8.5214749477
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.3416002989
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.0715688416
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 5.8611606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Selenium 5.8615318939
MESH:D008545 Melanoma Paclitaxel 3.6012040289 12025231 16342250
MESH:D008545 Melanoma resveratrol 3.6017992120
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4019513568
MESH:D008654 Mesothelioma Selenium 2.7215107826
MESH:D008659 Metabolic Diseases resveratrol 4.2217112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6216801185
MESH:D009006 Monosomy Azacitidine 5.9119299654
MESH:D009101 Multiple Myeloma Azacitidine 11.6419549372 18443271
MESH:D009101 Multiple Myeloma Paclitaxel 11.6414749477
MESH:D009101 Multiple Myeloma resveratrol 11.6414749477 17049120 17935668 16490592 16267019 17164350
MESH:D020528 Multiple Sclerosis, Chronic Progressive Aluminum 6.2017086897
MESH:D020529 Multiple Sclerosis, Relapsing-Remitting Aluminum 6.2017086897
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.7017962980
MESH:D009135 Muscular Diseases pirinixic acid 3.3416239165
MESH:D009190 Myelodysplastic Syndromes Azacitidine 3.9118720364 17611569 17596541 19805378
MESH:D009203 Myocardial Infarction pirinixic acid 5.5019151258
MESH:D009203 Myocardial Infarction resveratrol 5.5017015251 16317513 17188708 17125593 16456233 16525036
MESH:D017202 Myocardial Ischemia resveratrol 8.5617125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.5612213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.8116411023
MESH:D009205 Myocarditis resveratrol 4.5917322642
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 9.163581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 9.163581430 9029167
MESH:D009362 Neoplasm Metastasis Paclitaxel 9.1615867366
MESH:D009369 Neoplasms Diethylstilbestrol 4.7615313581
MESH:D009369 Neoplasms pirinixic acid 4.7617405874
MESH:D009374 Neoplasms, Experimental resveratrol 3.838985016
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2717954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1419348381 18481113
MESH:D009421 Nervous System Malformations Diethylstilbestrol 9.0911399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.0914600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.806679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 13.2418514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 13.2420387270
MESH:D019636 Neurodegenerative Diseases resveratrol 13.2417652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.2417929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9420387270
MESH:D009765 Obesity Dietary Fats 4.2918674790 17217161 20132043 21332399 16723640 18457598 19632207 20518802 11836018
MESH:D009765 Obesity pirinixic acid 4.2920558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.276482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.853988306
MESH:D010014 Osteolysis Paclitaxel 4.8115867366
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.0917513867
MESH:D010051 Ovarian Neoplasms Paclitaxel 2.9411161223
MESH:D010146 Pain Acetaminophen 2.2516870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.4116540662
MESH:D010190 Pancreatic Neoplasms Mitomycin 5.4115113037
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5311578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.317296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0812520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.306228378
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.0014722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.5015687265 16977796
MESH:D010954 Plasmacytoma Selenium 4.7215087411
MESH:D011014 Pneumonia Lipopolysaccharides 4.3811605937 12224865
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3918163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.4612371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.462563599
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 15.3117184923
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 15.3116679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 15.3111222880 11896295 11399792 11118676
MESH:D011471 Prostatic Neoplasms Azacitidine 2.2118324645
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.2115046698 17136230 15846301
MESH:D011471 Prostatic Neoplasms Paclitaxel 2.2116729912 17172428 16356831 17136230
MESH:D011471 Prostatic Neoplasms resveratrol 2.2117718901 17804756 16731767 17675339 15767336 17636462
MESH:D011537 Pruritus Ethinyl Estradiol 3.1415861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1716882103
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.4116325855
MESH:D015427 Reperfusion Injury pirinixic acid 6.2919058328
MESH:D015427 Reperfusion Injury resveratrol 6.2917520802 16317513 15827377 17058453 16314181
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.6210835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6718990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.253692021
MESH:D012878 Skin Neoplasms resveratrol 5.4515837718 8985016
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.4516192470
MESH:D013088 Spermatocele Diethylstilbestrol 11.1416709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 11.1416709447
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.6118456281
MESH:D013274 Stomach Neoplasms Paclitaxel 2.6118506536 18396642
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.3316321402
MESH:D024801 Tauopathies Paclitaxel 4.6416930453
MESH:D013921 Thrombocytopenia Lipopolysaccharides 4.0115821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7312697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 6.693712494 6582329 7505956 6587162 1399818
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.697505956
MESH:D014062 Tongue Neoplasms resveratrol 4.0616227395
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 4.968074119
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 4.9616712894 16452187 17306315
MESH:D014581 Urticaria Acetaminophen 2.8210982225
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 9.1616175088
MESH:D002583 Uterine Cervical Neoplasms resveratrol 9.1617473185
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.0014652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 15.1115809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 15.1114692618
MESH:D014594 Uterine Neoplasms resveratrol 15.1117044934
MESH:D014605 Uveitis Cyclosporine 3.811336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.2716513791 16002989
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3814671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.1317488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0815886252
MESH:D015430 Weight Gain Dietary Fats 3.5916723640
MESH:D014985 Xerophthalmia Cyclosporine 4.2717120751
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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