AutismKB 2.0

Annotation Detail for CD38


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Basic Information Top
Gene Symbol:CD38 ( T10 )
Gene Full Name: CD38 molecule
Band: 4p15.32
Quick LinksEntrez ID:952; OMIM: 107270; Uniprot ID:CD38_HUMAN; ENSEMBL ID: ENSG00000004468; HGNC ID: 1667
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04640Hematopoietic cell lineage
hsa04020Calcium signaling pathway
hsa04970Salivary secretion
hsa04972Pancreatic secretion
hsa00760Nicotinate and nicotinamide metabolism
hsa01100Metabolic pathways
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
bone density
IMMUNE
METABOLIC
lupus erythematosus
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of CD38 mRNAincreases expression 19933214
C120227 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Tretinoin results in increased expression of CD38 protein]decreases reaction|increases expression 17077328
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of CD38 mRNAincreases expression 18648102
C103303 alitretinoin alitretinoin results in increased expression of CD38 mRNAincreases expression 15964820
C103303 alitretinoin Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]increases expression|increases reaction 15964820
C103303 alitretinoin periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]]decreases reaction|increases expression|increases reaction 15964820
C068073 Am 580 Am 580 results in increased expression of CD38 proteinincreases expression 16329108
C068073 Am 580 PD 98059 inhibits the reaction [Am 580 results in increased expression of CD38 protein]decreases reaction|increases expression 16329108
C068073 Am 580 [Ro 25-6603 co-treated with Am 580] results in increased expression of CD38 proteinaffects cotreatment|increases expression 16329108
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CD38 mRNAaffects expression 16483693
D000968 Antimycin A Antimycin A results in increased expression of CD38 mRNAincreases expression 10491287
D001151 Arsenic Arsenic results in decreased expression of CD38 mRNAdecreases expression 19654921
D001542 Benomyl Benomyl results in decreased expression of CD38 mRNAdecreases expression 15885261
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD38 mRNAaffects cotreatment|increases expression 18164116
D003606 Dacarbazine [Dacarbazine co-treated with IFNA1 protein] results in increased expression of CD38 proteinaffects cotreatment|increases expression 11583285
D003606 Dacarbazine [Dacarbazine co-treated with IFNA2 protein] results in increased expression of CD38 proteinaffects cotreatment|increases expression 14669796
D003606 Dacarbazine Dacarbazine promotes the reaction [IFNA1 protein results in increased expression of CD38 protein]increases expression|increases reaction 16078447
D003633 Dichlorodiphenyl Dichloroethylene Dichlorodiphenyl Dichloroethylene results in decreased expression of CD38 mRNAdecreases expression 15885261
D004041 Dietary Fats Dietary Fats results in decreased expression of CD38 mRNAdecreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD38 mRNAaffects cotreatment|increases expression 18164116
D002117 Calcitriol Calcitriol results in increased expression of CD38 mRNAincreases expression 16329108
D004121 Dimethyl Sulfoxide Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]increases expression|increases reaction 15964820
D004121 Dimethyl Sulfoxide periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]]decreases reaction|increases expression|increases reaction 15964820
D004317 Doxorubicin Doxorubicin results in decreased expression of CD38decreases expression 16878501
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of CD38 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of CD38 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CD38 mRNAaffects cotreatment|increases expression 17942748
D005419 Flavonoids Flavonoids results in increased expression of CD38 mRNAincreases expression 18035473
D005472 Fluorouracil Fluorouracil affects the expression of CD38 mRNAaffects expression 16584549
D005485 Flutamide Flutamide results in decreased expression of CD38 mRNAdecreases expression 15885261
D009240 N-Formylmethionine Leucyl-Phenylalanine N-Formylmethionine Leucyl-Phenylalanine results in increased cleavage of CD38 proteinincreases cleavage 15494208
D009240 N-Formylmethionine Leucyl-Phenylalanine SB 203580 inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased cleavage of CD38 protein]decreases reaction|increases cleavage 15494208
D009675 Novobiocin Novobiocin results in increased expression of CD38 mRNAincreases expression 11853877
D009675 Novobiocin Novobiocin results in increased expression of CD38 proteinincreases expression 11853877
D009840 Oligomycins Oligomycins results in increased expression of CD38 mRNAincreases expression 10491287
C041786 palm oil palm oil results in decreased expression of CD38 mRNAdecreases expression 18042831
C093973 PD 98059 PD 98059 inhibits the reaction [Am 580 results in increased expression of CD38 protein]decreases reaction|increases expression 16329108
C093973 PD 98059 PD 98059 inhibits the reaction [Ro 25-6603 results in increased expression of CD38 protein]decreases reaction|increases expression 16329108
C027579 periodate-oxidized adenosine periodate-oxidized adenosine inhibits the reaction [Dimethyl Sulfoxide promotes the reaction [alitretinoin results in increased expression of CD38 mRNA]]decreases reaction|increases expression|increases reaction 15964820
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of CD38 mRNA]affects reaction|decreases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of CD38 mRNAdecreases expression 19482888
D015474 Isotretinoin Isotretinoin results in increased expression of CD38 proteinincreases expression 16275619
C097599 Ro 25-6603 PD 98059 inhibits the reaction [Ro 25-6603 results in increased expression of CD38 protein]decreases reaction|increases expression 16329108
C097599 Ro 25-6603 [Ro 25-6603 co-treated with Am 580] results in increased expression of CD38 proteinaffects cotreatment|increases expression 16329108
C097599 Ro 25-6603 Ro 25-6603 results in increased expression of CD38 proteinincreases expression 16329108
D012402 Rotenone Rotenone results in increased expression of CD38 mRNAincreases expression 10491287
D012402 Rotenone Rotenone results in increased expression of CD38 proteinincreases expression 8833408
C093642 SB 203580 SB 203580 inhibits the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased cleavage of CD38 protein]decreases reaction|increases cleavage 15494208
D013629 Tamoxifen Tamoxifen affects the expression of CD38 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CD38 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CD38 mRNAincreases expression 19933214
D013853 Thioacetamide Thioacetamide results in increased expression of CD38 mRNAincreases expression 16343077
D013853 Thioacetamide Thioacetamide results in increased expression of CD38 proteinincreases expression 16343077
D014212 Tretinoin 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Tretinoin results in increased expression of CD38 protein]decreases reaction|increases expression 17077328
D014212 Tretinoin PTK2 protein inhibits the reaction [Tretinoin results in increased expression of CD38 protein]decreases reaction|increases expression 16226872
D014212 Tretinoin Tretinoin results in increased expression of CD38 mRNAincreases expression 16329108
16054129
D014212 Tretinoin Tretinoin results in increased expression of CD38 proteinincreases expression 16275619
16226872
16329108
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1714745880
MESH:D000014 Abnormalities, Drug-Induced Isotretinoin 12.2118769834
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 12.216195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 12.2115322242 11752688 14514962
MESH:D000015 Abnormalities, Multiple Isotretinoin 4.6518769834
MESH:D000138 Acidosis Ammonium Chloride 3.1918287403
MESH:D017486 Acneiform Eruptions Isotretinoin 5.9116232082
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 10.7517505938
MESH:D000152 Acne Vulgaris Isotretinoin 10.7518769834 16185265
MESH:D000230 Adenocarcinoma Doxorubicin 6.5117418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.5114692618
MESH:D000230 Adenocarcinoma Fluorouracil 6.5117638652
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 9.963712494
MESH:D000236 Adenoma beta-Naphthoflavone 9.9619389873
MESH:D000236 Adenoma Diethylnitrosamine 9.9610737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 15.2119061943 19052882 16434500 17620307 17162532 18056438
MESH:D018248 Adenoma, Liver Cell Phenobarbital 15.2117620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.2116835633
MESH:D018246 Adrenocortical Adenoma Arsenic 4.8417306315
MESH:D000382 Agricultural Workers' Diseases Dichlorodiphenyl Dichloroethylene 4.4416487989
MESH:D000419 Albuminuria Doxorubicin 4.1921441931
MESH:D000505 Alopecia Tretinoin 3.3315955085
MESH:D000740 Anemia Fluorouracil 7.6316511603 17963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.6311748828
MESH:D000853 Anophthalmos Benomyl 5.6915907663
MESH:D001005 Anus Neoplasms Dacarbazine 5.9112170190
MESH:D020261 Arsenic Poisoning Arsenic 2.7612569548 16251483 18414634 16835338
MESH:D001161 Arteriosclerosis Dietary Fats 8.7115238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 8.7111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.4415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.4416412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.1716292516
MESH:D001249 Asthma Tretinoin 2.2316456186
MESH:D050197 Atherosclerosis Arsenic 3.0312928151 19371607
MESH:D001471 Barrett Esophagus Tretinoin 4.0516935849
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 4.641440618 11289319
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.5112125929
MESH:D001778 Blood Coagulation Disorders Thioacetamide 13.5119483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 13.5116197459 16206674
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5315746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.3214601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.4917150277
MESH:D001943 Breast Neoplasms alitretinoin 7.7916344269
MESH:D001943 Breast Neoplasms Calcitriol 7.7911237771
MESH:D001943 Breast Neoplasms Dacarbazine 7.7917983394
MESH:D001943 Breast Neoplasms Dichlorodiphenyl Dichloroethylene 7.7915061365
MESH:D001943 Breast Neoplasms Dietary Fats 7.7920435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 7.7917474063
MESH:D001943 Breast Neoplasms Doxorubicin 7.7919526202 18234424 18695136 16264153 15939500 16826403 15136595 17426702 11325840 15634643 15668708 15567936 17369602 16935488 18628466 16322301 17983394 16595493 16115903 15994142 16096432 18382427 15993339 15692762
MESH:D001943 Breast Neoplasms Fluorouracil 7.7916110121 16595493 15136595 18357371 19217205 16557594 18608205
MESH:D001943 Breast Neoplasms Tamoxifen 7.7919288272 16202921 17261762 20544844 18821012 20005174 18997820 19142967 20065188 15565566 20390343 18351453 19066611 18984771 17049068 20135344 19244106 18425577 16818667 19289846 19487384 18629630 19103187 15668708 17440819 11161223 19059307 18855134 17242785 19155303 19410462 21152245 21138602 19200415 16273361 16873071 17893378 19189210 19011961 19115204 19084267 20859285 18815881 19189212 19221464
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 7.7920435547
MESH:D001943 Breast Neoplasms Tretinoin 7.7916166294 16443354 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2216813970
MESH:D002276 Carcinoid Tumor Dacarbazine 19.1316051944
MESH:D002276 Carcinoid Tumor Doxorubicin 19.1316051944
MESH:D002276 Carcinoid Tumor Fluorouracil 19.1316051944
MESH:D002277 Carcinoma Fluorouracil 7.2317121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.2316835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.3815504454 17687452
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1519066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.7816168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 18.543581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Arsenic 18.5417306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 18.5420214788 10737359 19919837 19394651 16698587 3581430 19107877 16681979 19208518 21159647 16569478 19052882 16830150 17428255 16540662 18665156 16935385 20512989 19383236 20101231 18978308 16779866 16502159 18494052 17055752 20432363 18506893 19335982 17138121 11831363 19171122 3084413 17978847 20007298 19539802 16807293 20727157 18210153 16288022 18691550 17173139 17162532 10672840 18785209 16328049 20935162 18788625 20084675 20514400 18056438 16878318 17761372 18393292 18971187 19701751 19822196 20524982 19418558 19519916
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 18.5418059187 16234567 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 18.5418930000 17045692 16799960 16332177 17971768 17088986
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 18.5417173139 20007298 20935162 6705139 1701930
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 18.5416924424
MESH:D006528 Carcinoma, Hepatocellular Thioacetamide 18.5417997003
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 18.541917145
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 13.967296757
MESH:D002292 Carcinoma, Renal Cell Dacarbazine 13.9616201981
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 13.961485588 16201981
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 13.9618695887
MESH:D002294 Carcinoma, Squamous Cell Arsenic 16.5518922899 15504454 17687452
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 16.5511237771
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 16.556189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 16.5516280240 18986760 16757204 17066447
MESH:D002294 Carcinoma, Squamous Cell Isotretinoin 16.5511237771
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 16.5516051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Arsenic 8.4518640142
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.4517572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.1618850075 16120746 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 3.2916269455 16109756 17928571 17329180 16731534 15505089 16952015 17131338 16651473 17519947 16278810 15476868 17974986 18627295 16242529 17308081 15792986 16455267 17924179 17351982 17382496 16364871 16612575 17007740 15811867
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8117334414 16243910
MESH:D002318 Cardiovascular Diseases Arsenic 3.2015738583 19152805 17938729
MESH:D002340 Carotid Artery Diseases Arsenic 4.0018022660 16973168
MESH:D002386 Cataract Am 580 7.1517460283
MESH:D002386 Cataract Tretinoin 7.1517460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 5.857505956
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 5.8521159647 17174075 7505956 2727394
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.894080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2216129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 14.3419052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 14.3416835633
MESH:D018281 Cholangiocarcinoma Thioacetamide 14.3418291259
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 6.969022650 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 6.9615861022 17333356 11677210 17681005 16105132 17110522 16919318
MESH:D002822 Choriocarcinoma Tretinoin 4.7816461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.2315340226 16354765 12621046 8697196 15668235
MESH:D002972 Cleft Palate Tretinoin 5.239407595
MESH:D003092 Colitis Am 580 8.7417035595
MESH:D003092 Colitis Tretinoin 8.7417035595
MESH:D003110 Colonic Neoplasms Fluorouracil 2.1718772588 16510598 17287894 17725105 16340194 15001691 17172411 17018589 17169374 17016597
MESH:D015179 Colorectal Neoplasms Dacarbazine 3.4815273666
MESH:D015179 Colorectal Neoplasms Doxorubicin 3.4818802399 18259882
MESH:D015179 Colorectal Neoplasms Fluorouracil 3.4818448328 17016601 16391804 18383874 17695437 14970324 16282729 17454858 16524972 15289873 20501625 18288408 16331619 17094418 18802399 17255274 17401013 18949393 18509181 17594712 16303861 15148649
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.7517141729 14669216
MESH:D019465 Craniofacial Abnormalities Isotretinoin 3.659879862 18769834
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.6520055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 3.659211117 16925845 9224671 10589399 14991402 17551590 9125849 8800419 9142499 9664655
MESH:D007644 Darier Disease Fluorouracil 4.4216733453
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0019031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.4612868966 14531868 8156756 2524372 11906362 8970840 18759878 11298694
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.152952479 3621924
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 3.8820387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.8817107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.1719279558
MESH:D004342 Drug Hypersensitivity Dacarbazine 4.7316508601
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 10.746679447 9022650 9328219 18648102 16192314 6482804 18692083 11289319 1440618 8291058 18289764 7440962 9653073
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 10.7419107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 10.7417416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 10.7420420201
MESH:D056486 Drug-Induced Liver Injury Thioacetamide 10.7412963478
MESH:D004362 Drug Toxicity Doxorubicin 7.2118602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.2111462148
MESH:D050171 Dyslipidemias Dietary Fats 3.1918367378
MESH:D004417 Dyspnea Dichlorodiphenyl Dichloroethylene 4.8916487989
MESH:D004421 Dystonia Phenobarbital 3.671851702
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.0711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.6916714409 18230668 15322242
MESH:D004489 Edema, Cardiac Tretinoin 10.6918230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 13.3215138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 13.3212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 13.3219031437
MESH:D018159 Endolymphatic Hydrops Dimethyl Sulfoxide 6.1920641076
MESH:D016889 Endometrial Neoplasms Doxorubicin 11.0917359293
MESH:D016889 Endometrial Neoplasms Tamoxifen 11.0916202921 17893378 19155303 20544844
MESH:D016889 Endometrial Neoplasms Tretinoin 11.0916569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.719294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.7818037988
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.753659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.503922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.7020417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.246401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.897750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.653659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.7416302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.183581430
MESH:D004938 Esophageal Neoplasms Fluorouracil 4.1816481741 16337965 17638652 15173087 16785472
MESH:D005124 Eye Abnormalities Benomyl 13.821914497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 13.8211564622
MESH:D005124 Eye Abnormalities Tretinoin 13.829664655 16938888
MESH:D005218 Fat Necrosis Thioacetamide 5.3516456712
MESH:D005234 Fatty Liver Dietary Fats 16.0817967931 18296743 19551842 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 16.0820387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 16.0815345470
MESH:D005234 Fatty Liver Tamoxifen 16.0814986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0116709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1011858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 4.646705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1614745880
MESH:D018222 Fibromatosis, Aggressive Dacarbazine 17.5219069698
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 17.5219069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 17.5219069698
MESH:D005355 Fibrosis Dietary Fats 12.6918296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.6920067830
MESH:D005355 Fibrosis Tretinoin 12.6917994277
MESH:D005534 Foot Diseases Arsenic 5.186392382
MESH:D005909 Glioblastoma Dacarbazine 10.7312592361 12853885
MESH:D005909 Glioblastoma Doxorubicin 10.7317150277
MESH:D005909 Glioblastoma Tretinoin 10.7317312396
MESH:D005910 Glioma Fluorouracil 2.7216145905
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 3.707505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2210696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 11.5415692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 11.5418337622 15102660 15162350
MESH:D006258 Head and Neck Neoplasms Tretinoin 11.5416096774
MESH:D034381 Hearing Loss Dimethyl Sulfoxide 4.8620641076
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.7816084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.8710048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 5.8714991402 9664655
MESH:D006331 Heart Diseases Doxorubicin 3.2317888722 14766674 16330681 16244371 16707910 12587719 18674790 18006777 17875725 16879835 16495754 16144979 16244372
MESH:D006333 Heart Failure Doxorubicin 3.1217481944
MESH:D006394 Hemangiosarcoma Doxorubicin 3.5715692506
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0111000095
MESH:D006501 Hepatic Encephalopathy Thioacetamide 4.2417276928 15929193 18665440
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 13.906705139
MESH:D006505 Hepatitis Dichlorodiphenyl Dichloroethylene 13.9016487989
MESH:D006505 Hepatitis Thioacetamide 13.9016456712
MESH:D006529 Hepatomegaly Phenobarbital 7.2516109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.2516120746 12621046 15340226
MESH:D006689 Hodgkin Disease Dacarbazine 7.0518501091 16170182
MESH:D006689 Hodgkin Disease Doxorubicin 7.0515147373 18501091 17606976
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6715340226 8697196 16354765 16959395 18606429
MESH:D006930 Hyperalgesia Tretinoin 2.9316870215
MESH:D017588 Hyperandrogenism Flutamide 5.0915356085
MESH:D006937 Hypercholesterolemia Dietary Fats 3.2721332399
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2116778211
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.1417050553
MESH:D006949 Hyperlipidemias Dietary Fats 3.2821332399
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.5815034207
MESH:D006973 Hypertension Arsenic 4.7411953799 16076760 9931084
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.7418850075 18670907
MESH:D006987 Hypesthesia Arsenic 5.1816093927
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1212013081
MESH:D007248 Infertility, Male Dichlorodiphenyl Dichloroethylene 6.3017192596 12948891
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.3017937319
MESH:D007249 Inflammation Dietary Fats 13.7520412841
MESH:D007249 Inflammation Diethylnitrosamine 13.7518785209
MESH:D007249 Inflammation Flavonoids 13.7517296493
MESH:D007249 Inflammation Tamoxifen 13.7519457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 13.7512200463 12878042
MESH:D007333 Insulin Resistance Dietary Fats 2.8711836018 18457598
MESH:D007410 Intestinal Diseases Tretinoin 3.4117994277
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 4.649022650 8074119
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.8416580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.8415992940 17551590
MESH:D007642 Keratosis Arsenic 4.6216930632 12749816
MESH:D017492 Keratosis, Seborrheic alitretinoin 5.2716144296
MESH:D007674 Kidney Diseases Doxorubicin 2.8515369732 15699352 16775033
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.8316707910
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 10.746582329
MESH:D007680 Kidney Neoplasms Fluorouracil 10.7416985049
MESH:D007680 Kidney Neoplasms Tamoxifen 10.7418625569
MESH:D007938 Leukemia Tretinoin 2.5817143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.7816085563
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 4.8616972261
MESH:D007951 Leukemia, Myeloid Tretinoin 3.3719285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide 4.3617077328 16467208
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 4.3619850784 17596541 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide 11.6417077328
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 11.6417339181
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 11.6416823087 16331271 17361223 15748426 17649720 16935935 17294898 16766008 17339181 19029980 19035177 17506722 16891316 17301526 9834237 12679006 17107899 17368321 17217047 19225113 19642359 19075265 16140955 16788101 17712046
MESH:D017880 Limb Deformities, Congenital Dichlorodiphenyl Dichloroethylene 7.7712745335
MESH:D017880 Limb Deformities, Congenital Tretinoin 7.779224671
MESH:D008064 Lipidoses Tamoxifen 2.8915342952 17567588
MESH:D008103 Liver Cirrhosis Dietary Fats 9.8218296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 9.8218665156 18407596 18522880 20032147 19638242
MESH:D008103 Liver Cirrhosis Phenobarbital 9.8221047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 2.979327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Dimethyl Sulfoxide 8.0611682029
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 8.0616439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 8.0618564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 8.0612878042
MESH:D008106 Liver Cirrhosis, Experimental Thioacetamide 8.0616098781 18031379 17050028 17355460 18032466 15474484 12891558 11682029 18615449 15095483 11172339 15158331 18606216 15716488 17127702 16343077 11481614 17629604 10677585 15288472 14739098 18295389 16126171 16248980 18263696 12175628 12531686 15362042 18395095 15465738 15334695 16097051 12679928 16489207 15316131 18458672 16511523 17292413 15075984 18380797 12557150 18416461 12085344 15288473 15078482
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 8.0616248980 18397230
MESH:D008107 Liver Diseases Arsenic 8.5611134558
MESH:D008107 Liver Diseases Diethylnitrosamine 8.5617034775
MESH:D008107 Liver Diseases Phenobarbital 8.5619363144
MESH:D008107 Liver Diseases Thioacetamide 8.5618374380 15158337 16337175
MESH:D017114 Liver Failure, Acute Thioacetamide 3.9915633222 15313186 17276928 12479984
MESH:D008113 Liver Neoplasms Arsenic 19.6116368122
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 19.6121295105 19389873
MESH:D008113 Liver Neoplasms Diethylnitrosamine 19.6119690152 2862719 20452335 21167192 12112319 20118626 20137499 18977376 12771043 21071580 19499222 19996281 19638242 19642983 19294768 19255062 19426721 20583210 21278145 19254457 19850985 20101389 19833225 15175105 21047994 18648771 19812893 18978307 10737359 19427195 9163691 2422723 19090486 16942905 20434301 18754104 20492335 19073162 20405173 20501860 19256749 18644402 15885732 19551842
MESH:D008113 Liver Neoplasms Fluorouracil 19.6117045692 18383874 16603448 15113037
MESH:D008113 Liver Neoplasms Phenobarbital 19.6119812893 19482888 15975961 19073162 8742319 21047994
MESH:D008113 Liver Neoplasms Tamoxifen 19.6116684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 19.6116984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 20.366587162 3712494 598648 1399818
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 20.3618164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 20.369362446 17942915 21159647 18093689 17174075 17854601 18308698 18775883 18282651 18253720 16842330 19004024 19519916 18544905 18079962 2563599 16267830 18164116 19539802 19126423 19009564 3124819
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 20.3617085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 20.362563599 6150874 18308698 17172636 1399818
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 20.3612151625
MESH:D008175 Lung Neoplasms alitretinoin 12.0616413115
MESH:D008175 Lung Neoplasms Arsenic 12.0619168569 17306315 17976673
MESH:D008175 Lung Neoplasms Diethylnitrosamine 12.0620970405 20512841 21163286 6695378
MESH:D008175 Lung Neoplasms Doxorubicin 12.066189445 17418594
MESH:D008175 Lung Neoplasms Fluorouracil 12.0615246190
MESH:D008175 Lung Neoplasms Isotretinoin 12.0615899809
MESH:D008175 Lung Neoplasms Tamoxifen 12.0618625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 12.0619555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.4215086387
MESH:D008223 Lymphoma Doxorubicin 3.2016098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.4917654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.2115621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3919428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 5.3615458769
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 5.3619196722 16827153 11731420 19196723 14580682
MESH:D020149 Manganese Poisoning Tamoxifen 4.1719453300
MESH:D008527 Medulloblastoma Tretinoin 2.6317453147
MESH:D008545 Melanoma Dacarbazine 9.0316248763 16939954 10623706 15522559 17709802 11712820 16928243 17508024 18281670 17334785 12417787 16034308 15577320 17761969 15176220 12640292 12202904 12535206 12439608 18089842 11135225 12556972 18176117 17973783 12393984 12025231 16225601 17119449 12883367 17562445 18332650 15020614 11746506 18505091 16273263 17623835 16098027 11254118 16966688 16760174 18445842 17023156 17239242 16809738 16508601 15917704 17576460 15577323
MESH:D008545 Melanoma Doxorubicin 9.0316827129
MESH:D008545 Melanoma Isotretinoin 9.0317237267
MESH:D008545 Melanoma Tamoxifen 9.0319393235 12393984
MESH:D008545 Melanoma Tretinoin 9.0316752155
MESH:D018328 Melanoma, Amelanotic Dacarbazine 10.7115990972
MESH:D018328 Melanoma, Amelanotic Tamoxifen 10.7115990972
MESH:D008591 Meningomyelocele Tretinoin 4.0616940565
MESH:D008654 Mesothelioma Doxorubicin 2.9117638057
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.1715792986
MESH:D009062 Mouth Neoplasms Fluorouracil 3.3516757204 18986760
MESH:D052016 Mucositis Doxorubicin 4.4217415656
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.8717596541
MESH:D009203 Myocardial Infarction Doxorubicin 2.7915857846 19429709
MESH:D017202 Myocardial Ischemia Arsenic 8.0415371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.0412213967
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.1117484760
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 12.303581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 12.303581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 12.3018259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 12.3019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3919410462
MESH:D009369 Neoplasms alitretinoin 7.3316946489
MESH:D009369 Neoplasms Fluorouracil 7.3316928823 18239605 18600527
MESH:D009369 Neoplasms Tretinoin 7.3316946489 16594593
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.6319200415 19189210 19196722
MESH:D009401 Nephrosis Doxorubicin 4.4116636307 16899518
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.6916889571 15640375
MESH:D009410 Nerve Degeneration Rotenone 3.6015790535 17356569 18619942
MESH:D009421 Nervous System Malformations Benomyl 14.5614502586
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 14.5614600291
MESH:D009421 Nervous System Malformations Tretinoin 14.569125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 10.776679447
MESH:D009436 Neural Tube Defects Arsenic 10.7716620997
MESH:D009436 Neural Tube Defects Tretinoin 10.779142499
MESH:D009447 Neuroblastoma Doxorubicin 6.7115555623
MESH:D009447 Neuroblastoma Isotretinoin 6.7117368321
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.0520387270
MESH:D020078 Neurogenic Inflammation Arsenic 4.0417056641
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.7420387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.1916436463
MESH:D009765 Obesity Dietary Fats 2.1917217161 18674790 20518802 19632207 21332399 18457598 20132043 16723640 11836018
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.104026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 4.643988306
MESH:D010018 Osteomalacia Phenobarbital 4.0017016548
MESH:D012516 Osteosarcoma Doxorubicin 3.8215930896
MESH:D010051 Ovarian Neoplasms Arsenic 4.5817306315
MESH:D010051 Ovarian Neoplasms Tretinoin 4.5816936753
MESH:D010146 Pain Tretinoin 2.6216870215
MESH:D010190 Pancreatic Neoplasms Dacarbazine 14.8311583197
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 14.8316540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 14.8319003803 16929163 15113037 16500647
MESH:D010190 Pancreatic Neoplasms Phenobarbital 14.8316965848
MESH:D010190 Pancreatic Neoplasms Tretinoin 14.8315976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3511578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.137296757
MESH:D010300 Parkinson Disease Rotenone 2.8415451049 16412576 18191903 18619942 19114014 11445065 19232380 11535288 16140633
MESH:D020734 Parkinsonian Disorders Rotenone 3.7615795934 18197244 15927086 15574749
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8712520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 3.8316093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 4.6215371236 6392382 16905509
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.106228378
MESH:D003557 Phyllodes Tumor Dacarbazine 13.1117983394
MESH:D003557 Phyllodes Tumor Doxorubicin 13.1117983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.7817638057
MESH:D011085 Polycystic Ovary Syndrome Flutamide 4.6815356085
MESH:D017499 Porokeratosis alitretinoin 5.6316144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2118163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.072563599
MESH:D011230 Precancerous Conditions Phenobarbital 8.072563599
MESH:D011297 Prenatal Exposure Delayed Effects Isotretinoin 8.6318769834
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.6311118676 11399792 11896295 11222880
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.4115572423
MESH:D011471 Prostatic Neoplasms Arsenic 1.8816140617
MESH:D011471 Prostatic Neoplasms Calcitriol 1.8812479363 15754350 16644109 18247401 16289102
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.8818437689 16888761 15897917 16868541 16729912 15749863
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8819082440 18626508
MESH:D011471 Prostatic Neoplasms Flutamide 1.883169114
MESH:D011471 Prostatic Neoplasms Tamoxifen 1.8815067354
MESH:D011507 Proteinuria Arsenic 8.1521343184
MESH:D011507 Proteinuria Tretinoin 8.1516636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.9516919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 4.1212752131
MESH:D011596 Psychomotor Disorders Isotretinoin 5.5518769834
MESH:D011625 Pterygium Tretinoin 4.4216723453
MESH:D012004 Rectal Neoplasms Fluorouracil 3.7016160472 15538739 18722050 18286688
MESH:D051437 Renal Insufficiency Doxorubicin 3.8617922066
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4918990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.103692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.7616283617 16116481
MESH:D012509 Sarcoma Dacarbazine 8.9617898927 18313854
MESH:D012509 Sarcoma Doxorubicin 8.9615625365 17710206 16767912 17203757 15675481 18313854
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.8916326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.4217846226
MESH:D012640 Seizures Phenobarbital 2.453137016 11442880 4039156 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.456407741
MESH:D012871 Skin Diseases Arsenic 2.656392382 17050553 19834688 17453740 16759981 15952646 16353154 18709164 16702368 17938729 17548696
MESH:D012878 Skin Neoplasms Arsenic 12.1017029826 15504454 16251483 19538983 17050553 17976673
MESH:D012878 Skin Neoplasms Doxorubicin 12.1015692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 12.1016192470
MESH:D012878 Skin Neoplasms Tretinoin 12.1016467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2115625365 16767912 17203757
MESH:D013088 Spermatocele Ethinyl Estradiol 10.3116709447
MESH:D013088 Spermatocele Tamoxifen 10.3116709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.6719457130
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.1618456281
MESH:D013274 Stomach Neoplasms Fluorouracil 3.1618396642 19084572 16951190 17172411 19015929 17498489 17522103 18567086 16424979 15786421
MESH:D013274 Stomach Neoplasms Tretinoin 3.1617261132
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8515669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5312697716
MESH:D013964 Thyroid Neoplasms 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide 29.5316940797
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 29.531399818 6582329 3712494 7505956 6587162
MESH:D013964 Thyroid Neoplasms Dacarbazine 29.5315634649 11815960
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 29.537505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 29.5316010429 17909728
MESH:D013964 Thyroid Neoplasms Phenobarbital 29.531399818
MESH:D013964 Thyroid Neoplasms Tretinoin 29.5316026305 17045167
MESH:D014062 Tongue Neoplasms Fluorouracil 8.7716280240
MESH:D014062 Tongue Neoplasms Tretinoin 8.7716051514
MESH:D014376 Tuberculosis Tretinoin 3.0016040207
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 10.698074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 10.6919322015 17306315 17976673 11144890 15987713 19429237 18640142
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 10.6917653716
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 10.6917572228 8653321 16712894
MESH:D014570 Urologic Diseases Dichlorodiphenyl Dichloroethylene 5.3716487989
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 8.4016803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.4016129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.9514692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.2416752155
MESH:D014625 Vaginal Neoplasms Dacarbazine 5.4015577323
MESH:D014652 Vascular Diseases Arsenic 4.3717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2212125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2115869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.8617638931 17334414 16364871 17678736
MESH:D014820 Vitiligo Tretinoin 3.7116761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8715886252
MESH:D015430 Weight Gain Dietary Fats 3.4316723640
MESH:D009396 Wilms Tumor Tretinoin 3.6616287080
Pathway ID Pathway Name
KEGG:04020 Calcium signaling pathway
KEGG:04640 Hematopoietic cell lineage
KEGG:01100 Metabolic pathways
KEGG:00760 Nicotinate and nicotinamide metabolism
KEGG:04972 Pancreatic secretion
KEGG:04970 Salivary secretion
Pharmacogenomics Knowledge Base Top
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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