Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
---|
C472791 |
3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid |
3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of BAG4 mRNA | increases expression | 16788091
|
D000082 |
Acetaminophen |
Acetaminophen affects the expression of BAG4 mRNA | affects expression | 17562736
|
D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in decreased expression of BAG4 mRNA | decreases expression | 20504355
|
D019207 |
beta Carotene |
beta Carotene results in decreased expression of BAG4 mRNA | decreases expression | 17034753
|
D002251 |
Carbon Tetrachloride |
Carbon Tetrachloride results in decreased expression of BAG4 mRNA | decreases expression | 15963578
|
D016572 |
Cyclosporine |
Cyclosporine results in decreased expression of BAG4 mRNA | decreases expression | 20106945
|
D004041 |
Dietary Fats |
Dietary Fats results in decreased expression of BAG4 mRNA | decreases expression | 18042831
|
C041786 |
palm oil |
palm oil results in decreased expression of BAG4 mRNA | decreases expression | 18042831
|
C006253 |
pirinixic acid |
pirinixic acid results in increased expression of BAG4 mRNA | increases expression | 18301758
|
C030984 |
pyrene |
pyrene results in decreased expression of BAG4 mRNA | decreases expression | 15963578
|
Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
---|
MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.30 | 18653653 |
MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.02 | 20127859 20464547 |
MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.74 | 6695378 |
MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
3.72 | 16434500 |
MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.11 | 10982225 |
MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.29 | 19183758 |
MESH:D001161 |
Arteriosclerosis |
|
Dietary Fats |
4.10 | 15238619 |
MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.41 | 18445737 |
MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.32 | 19483382 |
MESH:D002545 |
Brain Ischemia |
|
beta Carotene |
5.33 | 16157235 |
MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
2.09 | 17474063 20146248 |
MESH:D001943 |
Breast Neoplasms |
|
Dietary Fats |
2.09 | 20435547 |
MESH:D002252 |
Carbon Tetrachloride Poisoning |
|
Carbon Tetrachloride |
3.99 | 3786805 16124888 16192424 16097048 16050911 16011737 15721981 15673190 16227642 18705752 15700767 10355542 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
2.91 | 3084413 |
MESH:D006528 |
Carcinoma, Hepatocellular |
|
Carbon Tetrachloride |
2.91 | 18788625 |
MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
2.09 | 20419170 |
MESH:D002386 |
Cataract |
|
Acetaminophen |
2.67 | 10977129 |
MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.64 | 12371664 |
MESH:D002779 |
Cholestasis |
|
Cyclosporine |
8.18 | 19486331 |
MESH:D002779 |
Cholestasis |
|
pirinixic acid |
8.18 | 19176532 |
MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.49 | 18249437 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
3.89 | 15968718 12153990 16485898 14550746 12392966 10663392 10774834 11739529 17562736 11743745 19420014 11529661 16393943 18713872 19370779 2444490 12594235 12540782 12705907 17906064 11421492 11287661 16081117 19923254 16177239 15619225 17522070 19164858 16781746 10915739 16227642 19739265 19085960 14725611 11834606 11461765 18071297 14986274 19416960 16109766 12958197 |
MESH:D056486 |
Drug-Induced Liver Injury |
|
Carbon Tetrachloride |
3.89 | 6623471 10915739 10092053 15968718 11566570 19085960 6884620 16177239 7120509 17522070 3732212 7440962 19336974 21278145 4309450 7179309 3786805 2869522 9327722 15027814 15998439 16227642 |
MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.36 | 19426721 |
MESH:D050171 |
Dyslipidemias |
|
Dietary Fats |
3.57 | 18367378 |
MESH:D004487 |
Edema |
|
pirinixic acid |
2.65 | 12083418 |
MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
2.04 | 16530937 |
MESH:D005234 |
Fatty Liver |
|
Carbon Tetrachloride |
20.24 | 12795759 17595544 16045604 61145 12631006 16239168 15959796 19224547 |
MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
20.24 | 19224547 |
MESH:D005234 |
Fatty Liver |
|
Dietary Fats |
20.24 | 18296743 19004024 19551842 17967931 |
MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
20.24 | 20131406 19236843 |
MESH:D005355 |
Fibrosis |
|
Carbon Tetrachloride |
16.10 | 18705752 |
MESH:D005355 |
Fibrosis |
|
Cyclosporine |
16.10 | 12168785 12639820 |
MESH:D005355 |
Fibrosis |
|
Dietary Fats |
16.10 | 18296743 |
MESH:D005756 |
Gastritis |
|
Acetaminophen |
3.94 | 16983495 |
MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.46 | 8708960 |
MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.74 | 20471113 |
MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.63 | 20558911 |
MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
4.66 | 15720958 |
MESH:D006505 |
Hepatitis |
|
Carbon Tetrachloride |
3.79 | 19900420 19110552 |
MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.21 | 16221962 18467677 19176532 19772884 |
MESH:D015658 |
HIV Infections |
|
beta Carotene |
4.12 | 16960176 |
MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.84 | 16870215 |
MESH:D006932 |
Hyperbilirubinemia |
|
Carbon Tetrachloride |
4.77 | 16899240 |
MESH:D006937 |
Hypercholesterolemia |
|
Dietary Fats |
3.76 | 21332399 |
MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.34 | 20558911 |
MESH:D006949 |
Hyperlipidemias |
|
Dietary Fats |
3.80 | 21332399 |
MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.15 | 10903974 |
MESH:D006975 |
Hypertension, Portal |
|
Carbon Tetrachloride |
4.30 | 15338365 |
MESH:D007249 |
Inflammation |
|
Dietary Fats |
2.51 | 20412841 |
MESH:D007333 |
Insulin Resistance |
|
Dietary Fats |
7.61 | 11836018 18457598 |
MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
7.61 | 16306350 |
MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
4.71 | 15604871 |
MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
6.10 | 15629191 12587719 |
MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
6.10 | 18776723 10903974 8314463 |
MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
2.88 | 12371664 |
MESH:D008103 |
Liver Cirrhosis |
|
Carbon Tetrachloride |
6.92 | 17334410 17157831 17174718 16943688 11408273 21278145 11903743 16239168 16221502 |
MESH:D008103 |
Liver Cirrhosis |
|
Dietary Fats |
6.92 | 18296743 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Carbon Tetrachloride |
2.37 | 16027843 18412020 15052691 17708605 18279442 17557913 17721639 17805973 10355542 12958196 17944888 18395914 15057751 12741479 18705752 15123356 18420326 16136751 16033810 15996030 18205269 16192424 13678700 15362042 12609069 18339082 18395095 15818738 16097048 15931870 11481614 17761835 17900296 15338365 14716833 16638106 14724832 18187930 15876570 17631135 17640975 17766677 12445421 18210741 18166357 16248980 12667390 17922224 17525996 18376398 18481824 12586293 20821823 12632512 18418968 12898905 18156304 12632514 18429990 15673190 18054572 17714472 15893842 12546737 16011737 14748882 17976157 18251166 12445418 15730626 17869086 15370692 18263696 15959796 14512876 18317297 16116963 17565644 14716496 18006644 18472332 17823541 18277467 12649538 12666154 15650968 14620537 17481882 12389079 17698563 18472094 15925388 16015684 |
MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
2.37 | 15474484 |
MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
4.03 | 19784758 19460945 11587558 12969438 12587719 19014921 16610002 16611625 |
MESH:D008107 |
Liver Diseases |
|
Carbon Tetrachloride |
4.03 | 15830285 17285989 15720792 16964402 16246199 |
MESH:D017093 |
Liver Failure |
|
Carbon Tetrachloride |
4.38 | 15123358 |
MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
9.95 | 17185352 16871587 |
MESH:D017114 |
Liver Failure, Acute |
|
Carbon Tetrachloride |
9.95 | 16899240 14706259 |
MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
7.72 | 20195826 21137059 |
MESH:D008113 |
Liver Neoplasms |
|
Carbon Tetrachloride |
7.72 | 19294768 |
MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
7.72 | 16377806 20007298 15890375 |
MESH:D008114 |
Liver Neoplasms, Experimental |
|
beta Carotene |
6.76 | 17113696 |
MESH:D008114 |
Liver Neoplasms, Experimental |
|
Carbon Tetrachloride |
6.76 | 12014681 15583823 |
MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
2.89 | 20464547 18520028 18816296 17053015 18569708 6695378 20064080 20869020 20135361 |
MESH:D008175 |
Lung Neoplasms |
|
beta Carotene |
2.89 | 16401635 |
MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
3.78 | 19513568 |
MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.05 | 16801185 |
MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.32 | 16381670 |
MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.72 | 16239165 |
MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.20 | 19151258 |
MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.08 | 16411023 |
MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
8.82 | 11141357 |
MESH:D009369 |
Neoplasms |
|
beta Carotene |
8.82 | 17051425 |
MESH:D009369 |
Neoplasms |
|
pirinixic acid |
8.82 | 17405874 |
MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
4.71 | 17954296 |
MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.44 | 18481113 19348381 |
MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.01 | 18514411 |
MESH:D009765 |
Obesity |
|
Dietary Fats |
4.56 | 18457598 21332399 16723640 19632207 20132043 17217161 11836018 20518802 18674790 |
MESH:D009765 |
Obesity |
|
pirinixic acid |
4.56 | 20558911 |
MESH:D010146 |
Pain |
|
Acetaminophen |
2.53 | 16870215 |
MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.37 | 12371664 |
MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
2.94 | 17292933 |
MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.28 | 16882103 |
MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.46 | 19058328 |
MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.44 | 10029692 19755658 |
MESH:D013272 |
Stomach Diseases |
|
beta Carotene |
5.33 | 17638125 |
MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
1.56 | 20155912 2093021 |
MESH:D013276 |
Stomach Ulcer |
|
beta Carotene |
4.43 | 12500499 |
MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
2.23 | 17053015 |
MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.16 | 10982225 |
MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.25 | 1336536 |
MESH:D015430 |
Weight Gain |
|
Dietary Fats |
3.89 | 16723640 |
MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
4.71 | 17120751 |