AutismKB 2.0

Annotation Detail for PTGES


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PTGES ( MGC10317,MGST-IV,MGST1-L1,MGST1L1,MPGES,PGES,PIG12,PP102,PP1294,TP53I12,mPGES-1 )
Gene Full Name: prostaglandin E synthase
Band: 9q34.11
Quick LinksEntrez ID:9536; OMIM: 605172; Uniprot ID:PTGES_HUMAN; ENSEMBL ID: ENSG00000148344; HGNC ID: 9599
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY66-374prostanoid biosynthesis
Pathway IDPathway Name
hsa00590Arachidonic acid metabolism
hsa01100Metabolic pathways
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1781Rheumatoid arthritis
1860Brain tumor
1901Endometriosis
2025Polyarthritis
1976Squamous cell cancer
1997Dental plaque
2010Viral hepatitis
2022Liver cancer
1796Labor, Premature
2231Arthritis
2237Neoplasm metastasis
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of PTGES mRNAincreases expression 16788091
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PTGES mRNAaffects expression 16483693
C006632 arsenic trioxide [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of PTGES mRNAaffects cotreatment|increases expression 18922899
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of PTGES mRNAaffects expression 20382639
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of PTGES mRNAincreases expression 15336504
C459604 candoxin candoxin results in decreased expression of PTGES mRNAdecreases expression 16309724
C105934 celecoxib [celecoxib co-treated with docetaxel] results in decreased expression of PTGES proteinaffects cotreatment|decreases expression 16052515
C105934 celecoxib celecoxib results in decreased expression of PTGES mRNAdecreases expression 16273290
D003474 Curcumin Curcumin analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGES mRNA]decreases reaction|increases expression 19243473
C014347 decitabine decitabine results in increased expression of PTGES mRNAincreases expression 15251184
C014347 decitabine [Tetrachlorodibenzodioxin co-treated with decitabine] results in increased expression of PTGES mRNAaffects cotreatment|increases expression 15251184
D003840 Deoxycholic Acid [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PTGES mRNAaffects cotreatment|increases expression 16556975
C067311 docetaxel [celecoxib co-treated with docetaxel] results in decreased expression of PTGES proteinaffects cotreatment|decreases expression 16052515
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of PTGES mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in increased expression of PTGES mRNAincreases expression 19619570
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of PTGES mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of PTGES mRNAincreases expression 17942748
C030691 gluconic acid [gluconic acid co-treated with Deoxycholic Acid] results in increased expression of PTGES mRNAaffects cotreatment|increases expression 16556975
C051890 irinotecan irinotecan metabolite results in increased expression of PTGES mRNAincreases expression 15956246
C051890 irinotecan irinotecan results in increased expression of PTGES mRNAincreases expression 15956246
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of PTGES mRNAincreases expression 17927823
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of PTGES proteinincreases expression 17927823
D008070 Lipopolysaccharides resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGES mRNA]decreases reaction|increases expression 17927823
D008070 Lipopolysaccharides resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGES protein]decreases reaction|increases expression 17927823
D008070 Lipopolysaccharides Curcumin analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGES mRNA]decreases reaction|increases expression 19243473
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of PTGES mRNAincreases expression 19243473
D018021 Lithium Chloride Lithium Chloride results in increased expression of PTGES proteinincreases expression 19692487
D018021 Lithium Chloride [Lithium Chloride results in increased expression of PTGES protein] which results in increased chemical synthesis of Dinoprostoneincreases chemical synthesis|increases expression 19692487
D018021 Lithium Chloride PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 mRNA]decreases expression|increases reaction 19692487
D018021 Lithium Chloride PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of AQP2 protein]decreases expression|increases reaction 19692487
D018021 Lithium Chloride PTGES protein promotes the reaction [Lithium Chloride results in decreased expression of SLC12A1 protein]decreases expression|increases reaction 19692487
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of PTGES mRNAincreases expression 20713471
C008493 methylselenic acid methylselenic acid results in decreased expression of PTGES mRNAdecreases expression 11830524
C528911 N-((4-(5,9-diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo(3,4-g)quinolin-7-yl)-3-methylbenzyl)sulfonyl)-2-(2-methoxyphenyl)acetamide N-((4-(5,9-diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo(3,4-g)quinolin-7-yl)-3-methylbenzyl)sulfonyl)-2-(2-methoxyphenyl)acetamide results in increased expression of PTGES mRNAincreases expression 18287210
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PTGES mRNAaffects binding|increases activity|increases expression 19710929
D015232 Dinoprostone [GPX2 protein affects the expression of PTGES protein] which affects the metabolism of Dinoprostoneaffects expression|affects metabolic processing 18479189
D015232 Dinoprostone [Lithium Chloride results in increased expression of PTGES protein] which results in increased chemical synthesis of Dinoprostoneincreases chemical synthesis|increases expression 19692487
D020849 Raloxifene [Raloxifene co-treated with ESR2 protein] results in decreased expression of PTGES mRNAaffects cotreatment|decreases expression 19059307
C059514 resveratrol resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGES mRNA]decreases reaction|increases expression 17927823
C059514 resveratrol resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGES protein]decreases reaction|increases expression 17927823
D012643 Selenium [Selenium co-treated with Vitamin E] results in increased expression of PTGES mRNAaffects cotreatment|increases expression 19244175
D012643 Selenium Selenium results in increased expression of PTGES mRNAincreases expression 19244175
D013629 Tamoxifen [Tamoxifen co-treated with ESR2 protein] results in decreased expression of PTGES mRNAaffects cotreatment|decreases expression 19059307
D013629 Tamoxifen Tamoxifen affects the expression of PTGES mRNAaffects expression 17555576
C011363 terephthalic acid terephthalic acid results in increased expression of PTGES mRNAincreases expression 16621493
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of PTGES mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PTGES mRNAdecreases expression 19619570
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with decitabine] results in increased expression of PTGES mRNAaffects cotreatment|increases expression 15251184
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of PTGES mRNAincreases expression 15328365
D013755 Tetradecanoylphorbol Acetate [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of PTGES mRNAaffects cotreatment|increases expression 18922899
D014212 Tretinoin Tretinoin results in increased expression of PTGES mRNAincreases expression 16788091
16604517
D014260 Triclosan Triclosan inhibits the reaction [TNF protein results in increased expression of PTGES mRNA]decreases reaction|increases expression 15642051
D014260 Triclosan Triclosan inhibits the reaction [TNF protein results in increased expression of PTGES protein]decreases reaction|increases expression 15642051
D014635 Valproic Acid Valproic Acid results in increased expression of PTGES mRNAincreases expression 15379904
D002762 Cholecalciferol Cholecalciferol results in increased expression of PTGES mRNAincreases expression 17170073
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in increased expression of PTGES mRNAaffects cotreatment|increases expression 19244175
D014810 Vitamin E Vitamin E results in increased expression of PTGES mRNAincreases expression 19244175
D015054 Zymosan Zymosan results in increased expression of PTGES mRNAincreases expression 15708354
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1914745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 7.1415322242 14514962 11752688
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 7.148875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.6119490988
MESH:D000138 Acidosis Ammonium Chloride 3.2118287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5817505938
MESH:D058186 Acute Kidney Injury resveratrol 3.5416538975
MESH:D055371 Acute Lung Injury Lipopolysaccharides 7.9618653653 11850527
MESH:D055371 Acute Lung Injury pirinixic acid 7.9618653653
MESH:D000230 Adenocarcinoma arsenic trioxide 6.4619825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 6.4611473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.4614692618
MESH:D000236 Adenoma Methylcholanthrene 6.4210545420 6695378
MESH:D000236 Adenoma resveratrol 6.4215688382
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.7216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.7216835633
MESH:D011125 Adenomatous Polyposis Coli celecoxib 9.4619003578 16215675
MESH:D011125 Adenomatous Polyposis Coli Dinoprostone 9.4617942926
MESH:D000419 Albuminuria Raloxifene 4.2617451421 17308373
MESH:D019973 Alcohol-Related Disorders Curcumin 4.7217887948
MESH:D000505 Alopecia Tretinoin 3.3415955085
MESH:D000544 Alzheimer Disease Curcumin 6.2115590663
MESH:D000544 Alzheimer Disease Raloxifene 6.2115800139
MESH:D000544 Alzheimer Disease resveratrol 6.2116162502 16183991
MESH:D000550 Amblyopia Valproic Acid 4.8717688650
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.9811748828
MESH:D000740 Anemia Zymosan 7.9818664788
MESH:D001008 Anxiety Disorders Valproic Acid 3.3017497229
MESH:D001014 Aortic Aneurysm Dinoprostone 5.2710231640
MESH:D017544 Aortic Aneurysm, Abdominal Dinoprostone 5.2810388637
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 20.7415885639
MESH:D001169 Arthritis, Experimental N-((4-(5,9-diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo(3,4-g)quinolin-7-yl)-3-methylbenzyl)sulfonyl)-2-(2-methoxyphenyl)acetamide 20.7418287210
MESH:D001169 Arthritis, Experimental resveratrol 20.7417115116
MESH:D001169 Arthritis, Experimental Tretinoin 20.7416412693
MESH:D001169 Arthritis, Experimental Zymosan 20.7416872482 15944321 15142272 15188379 17659584
MESH:D001172 Arthritis, Rheumatoid Curcumin 4.4216807698
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.4216292516
MESH:D001249 Asthma Tretinoin 2.2316456186
MESH:D050197 Atherosclerosis Curcumin 9.9018704882
MESH:D050197 Atherosclerosis Methylcholanthrene 9.9011922910
MESH:D050197 Atherosclerosis resveratrol 9.9016873680 17967414
MESH:D001321 Autistic Disorder Valproic Acid 2.0418177632 17507914 20603192 18985861 18775368 17688650 17157402 15238991 19460635 18558336 16609825 18316065 18940202 18396377 19232924
MESH:D001327 Autoimmune Diseases Cholecalciferol 9.9416142846
MESH:D001327 Autoimmune Diseases Curcumin 9.9419761891
MESH:D001471 Barrett Esophagus Tretinoin 4.0616935849
MESH:D001477 Bartter Syndrome Dinoprostone 5.3915976003
MESH:D001714 Bipolar Disorder Valproic Acid 2.8917594078 20046352
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 19.3516206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 19.3519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 19.3512125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 19.3516206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.4315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 7.2615746008
MESH:D001848 Bone Diseases, Developmental Valproic Acid 7.268888407
MESH:D001930 Brain Injuries Raloxifene 4.1316580743
MESH:D002545 Brain Ischemia Curcumin 9.1516770732
MESH:D002545 Brain Ischemia resveratrol 9.1517600658
MESH:D001932 Brain Neoplasms Curcumin 3.6317596214
MESH:D001943 Breast Neoplasms Curcumin 6.5818462866 18593918 16243823 19250217
MESH:D001943 Breast Neoplasms decitabine 6.5819208741 18320071
MESH:D001943 Breast Neoplasms docetaxel 6.5816264153 17369602 19526202 15567936 15692762 16495393 18628466
MESH:D001943 Breast Neoplasms Estradiol 6.5812948864 17018787 14630087 18497071 17289903 19861407 16675129 17261762
MESH:D001943 Breast Neoplasms Methylcholanthrene 6.5817474063
MESH:D001943 Breast Neoplasms Raloxifene 6.5817049068 17595753 15572757 17242785 17952589 15775269 17893378 16837676 15758505 17440819 16912660 17261762
MESH:D001943 Breast Neoplasms resveratrol 6.5817534123 17651959 16393696
MESH:D001943 Breast Neoplasms Tamoxifen 6.5820859285 20005174 17440819 19142967 19221464 19084267 19410462 18425577 19487384 19115204 17893378 11161223 21138602 19289846 17049068 18351453 19288272 16202921 16818667 19103187 17242785 15668708 17261762 18855134 16873071 20135344 19189210 18984771 18997820 19011961 19066611 19155303 20390343 18629630 20065188 19200415 18821012 15565566 18815881 19189212 19059307 21152245 16273361 20544844 19244106
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 6.5820435547
MESH:D001943 Breast Neoplasms Tretinoin 6.5816443354 16166294 16873071
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2416813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.0011589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1116111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.5916050911
MESH:D002277 Carcinoma Curcumin 12.4218593918
MESH:D002277 Carcinoma Methylcholanthrene 12.4210545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 12.4216835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1619066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8016168501
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 8.1814691202 16217749 15073043 11135700 15553829
MESH:D006528 Carcinoma, Hepatocellular Estradiol 8.1816924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 8.1819321006 16227395
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.1816924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 8.181917145
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.2416675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 5.7318414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung docetaxel 5.7311894018
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.5119014326
MESH:D002292 Carcinoma, Renal Cell celecoxib 4.0216369983
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8112490120
MESH:D002294 Carcinoma, Squamous Cell Curcumin 13.1518462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 13.1519215824
MESH:D002294 Carcinoma, Squamous Cell resveratrol 13.1516227395
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 13.1518922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 13.1516051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 8.4817572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 8.4817572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.1716120746 18850075 18670907
MESH:D002318 Cardiovascular Diseases Raloxifene 6.7515775269
MESH:D002318 Cardiovascular Diseases resveratrol 6.7515458977
MESH:D002386 Cataract Tretinoin 2.8817460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 14.1220889678
MESH:D002471 Cell Transformation, Neoplastic Dinoprostone 14.1216192471
MESH:D002471 Cell Transformation, Neoplastic Estradiol 14.1218566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 14.1216192471
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2416129372
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.5820734317
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8716835633
MESH:D002779 Cholestasis Ethinyl Estradiol 6.8816919318 16105132 17110522 17681005 11677210 17333356 15861022
MESH:D002779 Cholestasis pirinixic acid 6.8819176532
MESH:D002822 Choriocarcinoma Tretinoin 4.8016461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.2515340226 16354765 8697196 15668235 12621046
MESH:D002972 Cleft Palate Tretinoin 5.259407595
MESH:D003072 Cognition Disorders Raloxifene 4.2715800139
MESH:D003092 Colitis Curcumin 20.0116782535 16804969 18200517
MESH:D003092 Colitis resveratrol 20.0116474422
MESH:D003092 Colitis Selenium 20.0117936198
MESH:D003092 Colitis Tretinoin 20.0117035595
MESH:D003103 Coloboma Curcumin 4.2318809619
MESH:D003110 Colonic Neoplasms celecoxib 13.1316004971
MESH:D003110 Colonic Neoplasms Curcumin 13.1316340194 19359593
MESH:D003110 Colonic Neoplasms decitabine 13.1317616700
MESH:D003110 Colonic Neoplasms Deoxycholic Acid 13.1316213893
MESH:D003110 Colonic Neoplasms irinotecan 13.1317287894 17725105
MESH:D003110 Colonic Neoplasms resveratrol 13.1316338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 6.0820501625
MESH:D015179 Colorectal Neoplasms celecoxib 6.0811197048 18349538
MESH:D015179 Colorectal Neoplasms decitabine 6.0818981723
MESH:D015179 Colorectal Neoplasms irinotecan 6.0816391804 18259882 15273666 17159606 18509181 16303861 17454858
MESH:D015179 Colorectal Neoplasms resveratrol 6.0816550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.5614669216 17141729
MESH:D000013 Congenital Abnormalities Triclosan 8.5619283420
MESH:D016510 Corneal Neovascularization Curcumin 4.5518497527
MESH:D003327 Coronary Disease resveratrol 3.5216507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8512609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 6.8410525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 6.8410048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 6.848800419 17551590 9125849 9664655 9142499 16925845 9224671 14991402 9211117 10589399
MESH:D019465 Craniofacial Abnormalities Valproic Acid 6.8417688650 16575769 8888407
MESH:D019465 Craniofacial Abnormalities Vitamin E 6.8419769572
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7715213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.0219031437
MESH:D003865 Depressive Disorder, Major Raloxifene 3.8717474826
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2618249437
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.4916873680
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 4.0918403477
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.0917107852
MESH:D003928 Diabetic Nephropathies Curcumin 24.9218204486
MESH:D003928 Diabetic Nephropathies Estradiol 24.9219279558
MESH:D003928 Diabetic Nephropathies Raloxifene 24.9215920148 17451421 17308373
MESH:D003928 Diabetic Nephropathies resveratrol 24.9216286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 24.9219279558
MESH:D003967 Diarrhea Dinoprostone 4.2211488427 7237001 10446763
MESH:D056486 Drug-Induced Liver Injury Selenium 5.5615131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 5.5620420201
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 5.561733752 19641884
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5011462148
MESH:D004381 Duodenal Ulcer Curcumin 3.7217351913
MESH:D004421 Dystonia Valproic Acid 3.721851702
MESH:C538011 Eales disease Vitamin E 4.349068938
MESH:D004487 Edema pirinixic acid 22.9712083418
MESH:D004487 Edema Raloxifene 22.9715860553
MESH:D004487 Edema resveratrol 22.978985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 22.9711000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 22.978273558 15177302 8113982 16716910 7812673 11698051 9599246
MESH:D004487 Edema Zymosan 22.977907874
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.7418230668 16714409 15322242
MESH:D004489 Edema, Cardiac Tretinoin 10.7418230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 19.1812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 19.1815845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 19.1817872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 19.1819031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.7519294695
MESH:D016889 Endometrial Neoplasms Estradiol 11.0811473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tamoxifen 11.0817893378 16202921 19155303 20544844
MESH:D016889 Endometrial Neoplasms Tretinoin 11.0816569247
MESH:D004715 Endometriosis celecoxib 8.3515652904
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.3510568697 9294722
MESH:D019446 Endotoxemia Lipopolysaccharides 4.0415328337 15821434 17637181
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.5017923197
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.8117275665 3659116
MESH:D004828 Epilepsies, Partial Valproic Acid 3.563922381 16628512
MESH:D004827 Epilepsy Valproic Acid 2.7520417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.296254150 7562514 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 3.957750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.713659116
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.8620426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 6.8612903497
MESH:D004938 Esophageal Neoplasms docetaxel 6.8616337965
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.9611564622
MESH:D005124 Eye Abnormalities Tretinoin 7.969664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 32.1215073043
MESH:D005234 Fatty Liver Curcumin 32.1219297423
MESH:D005234 Fatty Liver Ethinyl Estradiol 32.1215345470
MESH:D005234 Fatty Liver pirinixic acid 32.1219236843 20131406
MESH:D005234 Fatty Liver Raloxifene 32.1217473493
MESH:D005234 Fatty Liver Tamoxifen 32.1214986274 19224547
MESH:D005234 Fatty Liver Valproic Acid 32.1214986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.0216709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.1111858732
MESH:D005315 Fetal Diseases Valproic Acid 4.5316575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.7918558336 8888407
MESH:D005334 Fever Dinoprostone 8.6216997862 11852909
MESH:D005334 Fever Lipopolysaccharides 8.6211852909 9205823
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1714745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.8319069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.5810962813 14633661
MESH:D005355 Fibrosis Curcumin 12.8318705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.8320067830
MESH:D005355 Fibrosis Tretinoin 12.8317994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.9316904648
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.3518462866
MESH:D005909 Glioblastoma Curcumin 6.5217596214
MESH:D005909 Glioblastoma Tretinoin 6.5217312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2310696789
MESH:D006258 Head and Neck Neoplasms Curcumin 11.6218829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 11.6219215824
MESH:D006258 Head and Neck Neoplasms Tretinoin 11.6216096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8016084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.0311294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 10.039664655 14991402
MESH:D006330 Heart Defects, Congenital Vitamin E 10.0316080930
MESH:D006331 Heart Diseases Raloxifene 3.2911110106
MESH:D006333 Heart Failure pirinixic acid 6.2220558911
MESH:D006333 Heart Failure Selenium 6.2217162251
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.0816366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0211000095
MESH:D006505 Hepatitis Zymosan 4.3619110552
MESH:D006529 Hepatomegaly pirinixic acid 7.1219176532 19772884 18467677 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.1215340226 12621046 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.6917701891
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.5716490937 16863852
MESH:D006558 Herpes Genitalis Estradiol 4.6715709030
MESH:D006561 Herpes Simplex resveratrol 3.8316876885
MESH:D019584 Hot Flashes Estradiol 8.8517088409
MESH:D019584 Hot Flashes Vitamin E 8.8514716179
MESH:D006849 Hydrocephalus Valproic Acid 4.5117688650
MESH:D006869 Hydronephrosis Lithium Chloride 11.8219797860
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 11.8216354765 8697196 18606429 16959395 15340226
MESH:D006930 Hyperalgesia Dinoprostone 7.3816793879
MESH:D006930 Hyperalgesia Tretinoin 7.3816870215
MESH:D006937 Hypercholesterolemia Curcumin 8.3418704882
MESH:D006937 Hypercholesterolemia resveratrol 8.3417188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2216778211
MESH:D006943 Hyperglycemia pirinixic acid 2.8820558911
MESH:D006949 Hyperlipidemias resveratrol 3.7016873680
MESH:D006973 Hypertension Raloxifene 4.7617577099 15787275
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.7618850075 18670907
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.0017488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4616569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.3017600658
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.1412013081
MESH:D007248 Infertility, Male decitabine 10.0517581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.0517937319
MESH:D007248 Infertility, Male Triclosan 10.0520821571
MESH:D007249 Inflammation Curcumin 25.3417151092 18403477 16956363
MESH:D007249 Inflammation Lipopolysaccharides 25.3417237260 17255318 12878042 9205823 17963957
MESH:D007249 Inflammation resveratrol 25.3416366677
MESH:D007249 Inflammation Tamoxifen 25.3419457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 25.3412878042 12200463
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 25.347812673 7562506 8273558 15177302 11698051
MESH:D007249 Inflammation Triclosan 25.349584910 20507366
MESH:D007249 Inflammation Zymosan 25.348014878 11289658
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.0618596194 18200517
MESH:D007251 Influenza, Human resveratrol 16.5316624496
MESH:D007251 Influenza, Human Selenium 16.5316624496
MESH:D007251 Influenza, Human Vitamin E 16.5316624496
MESH:D007333 Insulin Resistance Estradiol 6.4216393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 6.4216306350
MESH:D007410 Intestinal Diseases Tretinoin 3.4217994277
MESH:D007414 Intestinal Neoplasms Curcumin 3.9110783313
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.3017255318
MESH:D043183 Irritable Bowel Syndrome Zymosan 5.4817553498
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.8816580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.8817551590 15992940
MESH:D007674 Kidney Diseases Estradiol 5.4215618244
MESH:D007674 Kidney Diseases Vitamin E 5.4212488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.5716518626
MESH:D007680 Kidney Neoplasms Estradiol 6.4415610895
MESH:D007680 Kidney Neoplasms Tamoxifen 6.4418625569
MESH:D007889 Leiomyoma Curcumin 10.0718555241
MESH:D007889 Leiomyoma Raloxifene 10.0716973256
MESH:D007938 Leukemia arsenic trioxide 13.4915070760
MESH:D007938 Leukemia Curcumin 13.4918462866
MESH:D007938 Leukemia decitabine 13.4919235587 18980019
MESH:D007938 Leukemia Tretinoin 13.4917143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 8.7112560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 8.7116106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.9516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1714633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 14.1719077051
MESH:D007951 Leukemia, Myeloid decitabine 14.1719117987 17236224 18454857
MESH:D007951 Leukemia, Myeloid Tretinoin 14.1716932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 8.1419850784 16467208 16968895 17050201 20471514
MESH:D015470 Leukemia, Myeloid, Acute decitabine 8.1417679729 19387464 18460780 18206229 18704418 19010910
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 8.1417596541 19850784 16294345
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 8.1417596541 16294345
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.1018055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 11.4312712474 19225113 16330433 11161223 16331271 16823087 17107899 12679006 11468182 17649720 15748426 17869043 19075265 16966277 19035177 12018890 19642359 15622746 9834237 17217047 16112521 17712046 15336539 15213294 16891316
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 11.4316087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 11.4319075265 17506722 17339181 16823087 17217047 12679006 17712046 19029980 17649720 19225113 9834237 17301526 16140955 16766008 19035177 17368321 19642359 16788101 17361223 17294898 17107899 15748426 16891316 16331271 16935935
MESH:D015458 Leukemia, T-Cell arsenic trioxide 10.5916882451
MESH:D015458 Leukemia, T-Cell Curcumin 10.5916106398
MESH:D007970 Leukopenia Lipopolysaccharides 4.3415821434
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.069224671
MESH:D008064 Lipidoses Tamoxifen 2.9017567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 14.7017355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental Dinoprostone 14.7015816358
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 14.7014659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 14.7012878042
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 14.7015474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 14.7018564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 14.7012878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 14.7016248980 18397230
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 14.7016169303
MESH:D008107 Liver Diseases Curcumin 4.4416956363
MESH:D008107 Liver Diseases Dinoprostone 4.4415816358
MESH:D008113 Liver Neoplasms arsenic trioxide 12.7214682389
MESH:D008113 Liver Neoplasms pirinixic acid 12.7216377806 20007298 15890375
MESH:D008113 Liver Neoplasms resveratrol 12.7219812893 19073162 19321006 20405173
MESH:D008113 Liver Neoplasms Tamoxifen 12.7216684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 12.7216984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 12.3920377131
MESH:D008114 Liver Neoplasms, Experimental Deoxycholic Acid 12.396150874
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 12.39598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 12.3912151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0815213294
MESH:D008171 Lung Diseases Vitamin E 2.9416863852
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 3.9017228818
MESH:D055370 Lung Injury Lipopolysaccharides 3.6721114838
MESH:D008175 Lung Neoplasms arsenic trioxide 9.9319825857 11798837
MESH:D008175 Lung Neoplasms Curcumin 9.9319359593 18462866 16243823
MESH:D008175 Lung Neoplasms Methylcholanthrene 9.9321163286 15390079 11893704 7750092 16337739 20970405 17909032 1399818 20512841 16271038 6695378 9230183 10545420
MESH:D008175 Lung Neoplasms Tamoxifen 9.9318625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 9.9311884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 9.9311807781
MESH:D008175 Lung Neoplasms Vitamin E 9.9311062179
MESH:D008223 Lymphoma Curcumin 6.9418462866
MESH:D008223 Lymphoma decitabine 6.9419470736
MESH:D016393 Lymphoma, B-Cell resveratrol 3.9717088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.5814749477
MESH:D016399 Lymphoma, T-Cell Curcumin 4.3516173963
MESH:D015674 Mammary Neoplasms, Animal resveratrol 8.8215688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 8.8219428831
MESH:D008325 Mammary Neoplasms, Experimental celecoxib 25.0019196722 12104042
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 25.0017203775 11807958 11408345 16891317
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 25.0011606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Selenium 25.0015318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 25.0019196723 19196722 16827153 14580682 11731420
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 25.008985016
MESH:D008325 Mammary Neoplasms, Experimental Triclosan 25.0015358634
MESH:D020149 Manganese Poisoning Estradiol 11.4419453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.4419453300
MESH:D008527 Medulloblastoma Tretinoin 2.6417453147
MESH:D008545 Melanoma Curcumin 11.5818462866 17885582
MESH:D008545 Melanoma decitabine 11.5817785578 16505122
MESH:D008545 Melanoma docetaxel 11.5812417787
MESH:D008545 Melanoma resveratrol 11.5817992120
MESH:D008545 Melanoma Tamoxifen 11.5812393984 19393235
MESH:D008545 Melanoma Tretinoin 11.5816752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.8315990972
MESH:D008569 Memory Disorders Curcumin 3.8217263510
MESH:D008591 Meningomyelocele Tretinoin 4.0816940565
MESH:D008654 Mesothelioma Selenium 2.6515107826
MESH:D008659 Metabolic Diseases resveratrol 4.0617112576
MESH:D008881 Migraine Disorders Valproic Acid 2.9418765137 18803445
MESH:D020326 Migraine without Aura Dinoprostone 4.9311304026
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.1915863610
MESH:D052016 Mucositis irinotecan 4.6517159606
MESH:D009101 Multiple Myeloma arsenic trioxide 25.0011468182 19549372 19417148 15949261 14977855
MESH:D009101 Multiple Myeloma celecoxib 25.0016123214
MESH:D009101 Multiple Myeloma Curcumin 25.0019372569
MESH:D009101 Multiple Myeloma decitabine 25.0018172295
MESH:D009101 Multiple Myeloma Raloxifene 25.0016497877
MESH:D009101 Multiple Myeloma resveratrol 25.0017935668 17049120 14749477 16490592 17164350 16267019
MESH:D009102 Multiple Organ Failure Zymosan 4.8810479408 15259001 15241586 15834315 12130978 18160304 10890648 15213630 12879239 17724436
MESH:D009134 Muscular Atrophy, Spinal Curcumin 11.2317962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 11.2317962980
MESH:D009135 Muscular Diseases pirinixic acid 3.1616239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 3.718888407
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.3118349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 15.8816105982 16882451
MESH:D009190 Myelodysplastic Syndromes decitabine 15.8819157545 18608210 19010910 16882708
MESH:D009190 Myelodysplastic Syndromes Tretinoin 15.8817596541
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 15.8817596541
MESH:D009203 Myocardial Infarction pirinixic acid 5.2319151258
MESH:D009203 Myocardial Infarction resveratrol 5.2317188708 17015251 16456233 16525036 16317513 17125593
MESH:D017202 Myocardial Ischemia resveratrol 8.0917015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.0912213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.3516810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 7.3516411023
MESH:D009205 Myocarditis resveratrol 4.4017322642
MESH:D009232 Myxoma Raloxifene 5.1916343187
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 9.2116624393
MESH:D009361 Neoplasm Invasiveness Curcumin 9.2118495463
MESH:D009362 Neoplasm Metastasis irinotecan 5.4618259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.4619393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4019410462
MESH:D009369 Neoplasms decitabine 7.2117925555 19116145 19470736
MESH:D009369 Neoplasms pirinixic acid 7.2117405874
MESH:D009369 Neoplasms Tretinoin 7.2116594593 16946489
MESH:D009374 Neoplasms, Experimental resveratrol 3.668985016
MESH:D009376 Neoplasms, Hormone-Dependent celecoxib 16.3219196722
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 16.3212497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 16.3219200415 19196722 19189210
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3817289903
MESH:D009421 Nervous System Malformations Estradiol 14.3811399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 14.3814600291
MESH:D009421 Nervous System Malformations Tretinoin 14.389125849
MESH:D009423 Nervous System Neoplasms Curcumin 5.2718462866
MESH:D009436 Neural Tube Defects arsenic trioxide 10.8110525206
MESH:D009436 Neural Tube Defects Tretinoin 10.819142499
MESH:D009436 Neural Tube Defects Valproic Acid 10.818888407 16359493
MESH:D009447 Neuroblastoma irinotecan 3.308761367
MESH:D019636 Neurodegenerative Diseases resveratrol 3.5217652729
MESH:D017599 Neuroectodermal Tumors irinotecan 4.388761367
MESH:D020078 Neurogenic Inflammation resveratrol 4.0717929310
MESH:D009765 Obesity Curcumin 4.2819297423
MESH:D009765 Obesity pirinixic acid 4.2820558911
MESH:D010003 Osteoarthritis N-((4-(5,9-diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo(3,4-g)quinolin-7-yl)-3-methylbenzyl)sulfonyl)-2-(2-methoxyphenyl)acetamide 5.4518287210
MESH:D010005 Osteoarthropathy, Secondary Hypertrophic Dinoprostone 6.1118500342
MESH:D010024 Osteoporosis Curcumin 6.6818719352
MESH:D010024 Osteoporosis Raloxifene 6.6819059307 17882678 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 9.1217893378 15579764 17823083 15758505
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 9.1217513867
MESH:D010051 Ovarian Neoplasms arsenic trioxide 13.7012452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Curcumin 13.7019020741 18462866
MESH:D010051 Ovarian Neoplasms decitabine 13.7019331143 19259094
MESH:D010051 Ovarian Neoplasms Estradiol 13.7019401270
MESH:D010051 Ovarian Neoplasms Tretinoin 13.7016936753
MESH:D010146 Pain Tretinoin 2.6316870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 14.8915580305
MESH:D010190 Pancreatic Neoplasms Curcumin 14.8919401701 17440100 19196508
MESH:D010190 Pancreatic Neoplasms decitabine 14.8919294695
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 14.8915976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 14.8915976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3611578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 3.9518922899 12065085 18404319 8330346
MESH:D010235 Paraganglioma arsenic trioxide 3.8419927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8912520081
MESH:D010538 Peritonitis Zymosan 4.5418760300 19641140 17371808 18557954 15979727 15259001 11985352 17826846 18977430 19088179 14761945
MESH:D010954 Plasmacytoma Selenium 4.5315087411
MESH:D011014 Pneumonia Lipopolysaccharides 4.2011605937 12224865
MESH:D011141 Polyuria marker/mechanism 19692487
MESH:D011141 Polyuria Lithium Chloride 5.6419692487
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2218163543
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 14.2216679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 14.2211896295 11399792 11118676 11222880
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 14.2220603192
MESH:D055728 Primary Myelofibrosis decitabine 4.3817616702
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5720887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 4.0419131511
MESH:D011471 Prostatic Neoplasms celecoxib 4.0417908994 15570007
MESH:D011471 Prostatic Neoplasms Cholecalciferol 4.0417024972
MESH:D011471 Prostatic Neoplasms Curcumin 4.0411398177 15129424 18226269 10851300 18769126 18156803 12497104
MESH:D011471 Prostatic Neoplasms docetaxel 4.0418824434 16644109 16520278 19103299
MESH:D011471 Prostatic Neoplasms Estradiol 4.0416740699
MESH:D011471 Prostatic Neoplasms methylselenic acid 4.0416205645
MESH:D011471 Prostatic Neoplasms Raloxifene 4.0416536755 16220300 15731164
MESH:D011471 Prostatic Neoplasms resveratrol 4.0417636462 16731767 17718901 17675339 17804756 15767336
MESH:D011471 Prostatic Neoplasms Tamoxifen 4.0415067354
MESH:D011471 Prostatic Neoplasms Vitamin E 4.0415084515
MESH:D011507 Proteinuria Tretinoin 3.2816636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.9616919318 15861022
MESH:D019310 Pseudolymphoma Valproic Acid 4.1812752131 11422049
MESH:D011625 Pterygium Tretinoin 4.4416723453
MESH:D011656 Pulmonary Emphysema Curcumin 4.2219168576
MESH:D011693 Purpura Raloxifene 5.1915770314
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.2216325855
MESH:D015427 Reperfusion Injury pirinixic acid 5.9819058328
MESH:D015427 Reperfusion Injury resveratrol 5.9817058453 16314181 16317513 15827377 17520802
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.7010666014 18379247
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.5010835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5018990726
MESH:D012208 Rhabdomyosarcoma decitabine 16.6319155313
MESH:D012208 Rhabdomyosarcoma Tretinoin 16.6316116481 16283617
MESH:D012208 Rhabdomyosarcoma Valproic Acid 16.6319155313
MESH:D012509 Sarcoma Curcumin 3.8118462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.6216646077
MESH:D012559 Schizophrenia Valproic Acid 2.0219110320 15737665
MESH:D012640 Seizures Valproic Acid 2.513137016 11738929 1511512 14763951 11044598 16876388 17978042 15475178
MESH:D018805 Sepsis Curcumin 8.7318389075
MESH:D018805 Sepsis Zymosan 8.7311441115
MESH:D012871 Skin Diseases Vitamin E 2.3518709164
MESH:D012878 Skin Neoplasms resveratrol 16.1015837718 8985016
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 16.108532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 16.1016192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 16.1018404319 8985016 12065085 8330346 11807781
MESH:D012878 Skin Neoplasms Tretinoin 16.1016467112
MESH:D013088 Spermatocele Ethinyl Estradiol 10.3616709447
MESH:D013088 Spermatocele Tamoxifen 10.3616709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.6819457130
MESH:D016135 Spinal Dysraphism Valproic Acid 3.5119490988
MESH:D013226 Status Epilepticus Valproic Acid 4.1812833885
MESH:D013274 Stomach Neoplasms arsenic trioxide 7.7817007042
MESH:D013274 Stomach Neoplasms celecoxib 7.7815609394
MESH:D013274 Stomach Neoplasms decitabine 7.7819037991
MESH:D013274 Stomach Neoplasms docetaxel 7.7816557585
MESH:D013274 Stomach Neoplasms irinotecan 7.7815723263
MESH:D013274 Stomach Neoplasms Tretinoin 7.7817261132
MESH:D013276 Stomach Ulcer Curcumin 3.1916631530 19188055
MESH:D020521 Stroke Raloxifene 7.7916837676
MESH:D020521 Stroke Vitamin E 7.7916517955
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.1716321402
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.8615821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2911994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8615669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 11.3012697716
MESH:D013959 Thyroid Diseases Triclosan 11.3019910387
MESH:D013964 Thyroid Neoplasms arsenic trioxide 10.4819014326
MESH:D013964 Thyroid Neoplasms decitabine 10.4817967635
MESH:D013964 Thyroid Neoplasms Tretinoin 10.4817045167 16026305
MESH:D013978 Tibial Fractures Estradiol 12.5119048282
MESH:D013978 Tibial Fractures Raloxifene 12.5119048282
MESH:D014062 Tongue Neoplasms resveratrol 8.8916227395
MESH:D014062 Tongue Neoplasms Tretinoin 8.8916051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.6115213294
MESH:D014178 Translocation, Genetic Valproic Acid 4.8717262798
MESH:D014376 Tuberculosis Tretinoin 3.0116040207
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.173119515
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 18.0020435036 12845720 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms Curcumin 18.0018593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 18.0017616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 18.0017572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 18.008653321 17572228 16712894
MESH:D001749 Urinary Bladder Neoplasms terephthalic acid 18.0016896691 16621493
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.308888407
MESH:D014565 Urogenital Neoplasms Curcumin 4.9118462866
MESH:D002583 Uterine Cervical Neoplasms resveratrol 8.5217473185
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.5216129372
MESH:D014594 Uterine Neoplasms celecoxib 14.2618645019
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 14.2614692618
MESH:D014594 Uterine Neoplasms resveratrol 14.2617044934
MESH:D014604 Uveal Neoplasms decitabine 11.6317785578
MESH:D014604 Uveal Neoplasms Tretinoin 11.6316752155
MESH:D014605 Uveitis Zymosan 5.0411006244
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2312125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.8516837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2214671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 3.9617488730
MESH:D014820 Vitiligo Tretinoin 3.7216761959
MESH:D014846 Vulvar Neoplasms Raloxifene 5.1916343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8915886252
MESH:D009396 Wilms Tumor Tretinoin 3.6716287080
Pathway ID Pathway Name
KEGG:00590 Arachidonic acid metabolism
KEGG:01100 Metabolic pathways
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33948
    • Releated gene ID Related gene Name
    PA33948PTGES
    No data
    Releated drug ID Related drug Name
    PA449345dinoprostone
    PA449479epoprostenol
    PA164712740Epoxides
    PA448871celecoxib
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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