Annotation Detail for CDC42BPB
Basic Information
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| Gene Symbol: | CDC42BPB ( DKFZp686H1431,FLJ37601,FLJ44730,KIAA1124,MRCKB ) |
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| Gene Full Name: | CDC42 binding protein kinase beta (DMPK-like) |
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| Band: | 14q32.32 |
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| Quick Links | Entrez ID:9578; OMIM: NA; Uniprot ID:MRCKB_HUMAN; ENSEMBL ID: ENSG00000198752; HGNC ID: 1738 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Desease ID | Desease Name |
|---|
| 2115 | Muscular dystrophies |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of CDC42BPB mRNA | affects expression | 21346803
|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of CDC42BPB mRNA | affects expression | 21346803
|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of CDC42BPB mRNA | affects expression | 16483693
|
| D002118 |
Calcium |
Calcium affects the expression of CDC42BPB mRNA | affects expression | 15913539
|
| D005419 |
Flavonoids |
Flavonoids results in decreased expression of CDC42BPB mRNA | decreases expression | 18035473
|
| C030110 |
oxaliplatin |
oxaliplatin results in increased expression of CDC42BPB mRNA | increases expression | 17762391
|
| C025643 |
vinclozolin |
vinclozolin affects the expression of CDC42BPB mRNA | affects expression | 19015723
|
| C025643 |
vinclozolin |
vinclozolin results in decreased expression of CDC42BPB mRNA | decreases expression | 18042343
|
| D015032 |
Zinc |
Zinc affects the expression of CDC42BPB mRNA | affects expression | 16979875
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
3.90 | 18287403 |
| MESH:D000169 |
Acrodermatitis |
|
Zinc |
5.74 | 17202136 17190629 16889938 |
| MESH:D000544 |
Alzheimer Disease |
|
Zinc |
2.80 | 16580781 17119284 16325427 16410023 |
| MESH:D000755 |
Anemia, Sickle Cell |
|
Zinc |
5.18 | 16916123 |
| MESH:D001008 |
Anxiety Disorders |
|
vinclozolin |
3.83 | 19015723 |
| MESH:D001249 |
Asthma |
|
Zinc |
3.01 | 17085522 |
| MESH:D001930 |
Brain Injuries |
|
Zinc |
5.00 | 17109824 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
3.05 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
3.05 | 16705839 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Zinc |
2.95 | 16543248 |
| MESH:D002318 |
Cardiovascular Diseases |
|
Zinc |
3.82 | 16936243 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
2.93 | 6135515 |
| MESH:D003110 |
Colonic Neoplasms |
|
oxaliplatin |
3.20 | 16004971 16510598 16024531 |
| MESH:D015179 |
Colorectal Neoplasms |
|
oxaliplatin |
2.94 | 18509181 18448328 17695437 17594712 17255274 17401013 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Zinc |
2.44 | 19302082 |
| MESH:D003456 |
Cryptorchidism |
|
vinclozolin |
4.62 | 14966744 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
11.94 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
11.94 | 18551238 |
| MESH:D003920 |
Diabetes Mellitus |
|
Zinc |
4.42 | 16479319 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
4.05 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
4.05 | 18551238 21346803 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Zinc |
2.91 | 16543248 |
| MESH:D005756 |
Gastritis |
|
Zinc |
5.17 | 17241300 |
| MESH:D030342 |
Genetic Diseases, Inborn |
|
vinclozolin |
5.27 | 16973722 |
| MESH:D005832 |
Genital Diseases, Male |
|
vinclozolin |
5.68 | 16417039 |
| MESH:D006130 |
Growth Disorders |
|
Zinc |
4.10 | 17217573 |
| MESH:D006333 |
Heart Failure |
|
Zinc |
3.74 | 17162251 |
| MESH:D006335 |
Heart Injuries |
|
Zinc |
6.15 | 17074742 |
| MESH:D016481 |
Helicobacter Infections |
|
Zinc |
4.79 | 17241300 |
| MESH:D006527 |
Hepatolenticular Degeneration |
|
Zinc |
5.00 | 17276780 |
| MESH:D006930 |
Hyperalgesia |
|
oxaliplatin |
4.54 | 17418472 |
| MESH:D007248 |
Infertility, Male |
|
vinclozolin |
3.19 | 16467254 |
| MESH:D007249 |
Inflammation |
|
Flavonoids |
2.75 | 17296493 |
| MESH:D007511 |
Ischemia |
|
Zinc |
4.94 | 16584753 |
| MESH:D007674 |
Kidney Diseases |
|
Zinc |
3.44 | 16960431 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Zinc |
4.66 | 16518626 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
8.04 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.04 | 16705839 |
| MESH:D007683 |
Kidney Tubular Necrosis, Acute |
|
Calcium |
5.42 | 16316344 |
| MESH:D007984 |
Leydig Cell Tumor |
|
vinclozolin |
5.07 | 16417039 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.22 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.68 | 2876784 6135515 2876786 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Zinc |
3.44 | 12773700 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
11.50 | 18551238 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
11.50 | 18551238 7678174 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
9.66 | 16049721 12819281 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
9.66 | 16049721 |
| MESH:D010024 |
Osteoporosis |
|
Calcium |
3.92 | 17882678 |
| MESH:D011225 |
Pre-Eclampsia |
|
Zinc |
4.36 | 17114810 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
vinclozolin |
4.23 | 19015723 18042343 18220299 |
| MESH:D011469 |
Prostatic Diseases |
|
vinclozolin |
5.27 | 18220299 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Zinc |
3.78 | 12429649 16606632 16700911 16517595 |
| MESH:D011472 |
Prostatitis |
|
vinclozolin |
5.27 | 18629315 |
| MESH:D012162 |
Retinal Degeneration |
|
Zinc |
4.30 | 16584753 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.39 | 18551238 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
6.39 | 18551238 |
| MESH:D014062 |
Tongue Neoplasms |
|
Zinc |
4.63 | 16543248 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
5.28 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.28 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
13.14 | 10091137 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
13.14 | 10091137 |
Related Pathway Information