AutismKB 2.0

Annotation Detail for RBM39


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Basic Information Top
Gene Symbol:RBM39 ( CAPER,CAPERalpha,CC1.3,DKFZp781C0423,FLJ44170,HCC1,RNPC2,fSAP59 )
Gene Full Name: RNA binding motif protein 39
Band: 20q11.22
Quick LinksEntrez ID:9584; OMIM: 604739; Uniprot ID:RBM39_HUMAN; ENSEMBL ID: ENSG00000131051; HGNC ID: 15923
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RBM39 mRNAdecreases expression 19150397
D003474 Curcumin Curcumin results in increased expression of RBM39 mRNAincreases expression 17999991
D016572 Cyclosporine Cyclosporine results in increased expression of RBM39 mRNAincreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of RBM39 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of RBM39 mRNAincreases expression 17942748
C006253 pirinixic acid pirinixic acid results in decreased expression of RBM39 mRNAdecreases expression 17426115
C006253 pirinixic acid pirinixic acid results in increased expression of RBM39 mRNAincreases expression 16985257
18445702
D013629 Tamoxifen Tamoxifen affects the expression of RBM39 mRNAaffects expression 17555576
C025643 vinclozolin vinclozolin affects the expression of RBM39 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.9914745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.3817505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.4218653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8614692618
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.8816434500
MESH:D019973 Alcohol-Related Disorders Curcumin 5.5217887948
MESH:D000544 Alzheimer Disease Curcumin 2.6615590663
MESH:D001008 Anxiety Disorders vinclozolin 3.8619015723
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.8211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8215885639
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.7916807698
MESH:D050197 Atherosclerosis Curcumin 3.4718704882
MESH:D001327 Autoimmune Diseases Curcumin 4.8519761891
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.4319483382
MESH:D002545 Brain Ischemia Curcumin 4.7316770732
MESH:D001932 Brain Neoplasms Curcumin 4.2017596214
MESH:D001943 Breast Neoplasms Curcumin 2.3218593918 19250217 18462866 16243823
MESH:D001943 Breast Neoplasms Tamoxifen 2.3219189210 19066611 19200415 18997820 19115204 17242785 17893378 19103187 15668708 16818667 16873071 19410462 19221464 20135344 16202921 19288272 19189212 19289846 19142967 20859285 19011961 18821012 18815881 19059307 21152245 18425577 20544844 19155303 18855134 20390343 15565566 20005174 17440819 19244106 19084267 18984771 20065188 19487384 11161223 17261762 21138602 17049068 16273361 18351453 18629630
MESH:D002277 Carcinoma Curcumin 4.0618593918
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.8719066611
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 1.8516924424
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 3.0518414057
MESH:D002294 Carcinoma, Squamous Cell Curcumin 2.8218462866
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.8817572228
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.1720889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.1712371664
MESH:D002779 Cholestasis Cyclosporine 14.5419486331
MESH:D002779 Cholestasis Ethinyl Estradiol 14.5417110522 16105132 11677210 16919318 17333356 17681005 15861022
MESH:D002779 Cholestasis pirinixic acid 14.5419176532
MESH:D003092 Colitis Curcumin 4.5318200517 16782535 16804969
MESH:D003103 Coloboma Curcumin 4.8318809619
MESH:D003110 Colonic Neoplasms Curcumin 2.5419359593 16340194
MESH:D016510 Corneal Neovascularization Curcumin 5.2618497527
MESH:D003456 Cryptorchidism vinclozolin 4.6714966744
MESH:D003711 Demyelinating Diseases Tamoxifen 4.7219031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5318249437
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 2.7518403477
MESH:D003928 Diabetic Nephropathies Curcumin 9.9018204486
MESH:D003928 Diabetic Nephropathies Tamoxifen 9.9019279558
MESH:D004381 Duodenal Ulcer Curcumin 4.3817351913
MESH:D004487 Edema pirinixic acid 2.7612083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 10.0612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 10.0619031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.2116202921 20544844 19155303 17893378
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1320426865
MESH:D005234 Fatty Liver Curcumin 27.9319297423
MESH:D005234 Fatty Liver Cyclosporine 27.9319224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 27.9315345470
MESH:D005234 Fatty Liver pirinixic acid 27.9319236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 27.9314986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.3916709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.9214745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.5819069698
MESH:D005355 Fibrosis Curcumin 10.0818705752
MESH:D005355 Fibrosis Cyclosporine 10.0812168785 12639820
MESH:D005770 Gastrointestinal Neoplasms Curcumin 5.0518462866
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.3316973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.7416417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.628708960
MESH:D005909 Glioblastoma Curcumin 3.6417596214
MESH:D006258 Head and Neck Neoplasms Curcumin 3.8318462866 18829502
MESH:D006333 Heart Failure pirinixic acid 2.6920558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8215720958
MESH:D006529 Hepatomegaly pirinixic acid 3.3519176532 16221962 19772884 18467677
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 5.4017701891
MESH:D006937 Hypercholesterolemia Curcumin 4.3318704882
MESH:D006943 Hyperglycemia pirinixic acid 3.4520558911
MESH:D006973 Hypertension Cyclosporine 2.1810903974
MESH:D007021 Hypospadias Ethinyl Estradiol 4.1716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.7712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 7.2517937319
MESH:D007248 Infertility, Male vinclozolin 7.2516467254
MESH:D007249 Inflammation Curcumin 5.7018403477 17151092 16956363
MESH:D007249 Inflammation Tamoxifen 5.7019457130
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.3018596194 18200517
MESH:D007333 Insulin Resistance pirinixic acid 2.8016306350
MESH:D007414 Intestinal Neoplasms Curcumin 4.4810783313
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.8815604871
MESH:D007674 Kidney Diseases Cyclosporine 2.4818776723 10903974 8314463
MESH:D007680 Kidney Neoplasms Cyclosporine 8.0912371664
MESH:D007680 Kidney Neoplasms Tamoxifen 8.0918625569
MESH:D007889 Leiomyoma Curcumin 4.8818555241
MESH:D007938 Leukemia Curcumin 3.3618462866
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 4.4916106398
MESH:D015458 Leukemia, T-Cell Curcumin 5.0916106398
MESH:D007984 Leydig Cell Tumor vinclozolin 5.1316417039
MESH:D008064 Lipidoses Tamoxifen 3.3515342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 3.6717355460 18705752 18006644
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.6715474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.6718564211
MESH:D008107 Liver Diseases Curcumin 2.6616956363
MESH:D008113 Liver Neoplasms pirinixic acid 4.7315890375 16377806 20007298
MESH:D008113 Liver Neoplasms Tamoxifen 4.7316684651
MESH:D008175 Lung Neoplasms Curcumin 2.6918462866 19359593 16243823
MESH:D008175 Lung Neoplasms Tamoxifen 2.6918625569
MESH:D008223 Lymphoma Curcumin 3.7818462866
MESH:D016399 Lymphoma, T-Cell Curcumin 5.0516173963
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.1519428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.7911731420 16827153 14580682 19196723 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.9919453300
MESH:D008545 Melanoma Curcumin 3.5818462866 17885582
MESH:D008545 Melanoma Tamoxifen 3.5819393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.5815990972
MESH:D008569 Memory Disorders Curcumin 4.4817263510
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.2316801185
MESH:D009101 Multiple Myeloma Curcumin 3.7019372569
MESH:D009134 Muscular Atrophy, Spinal Curcumin 5.3117962980
MESH:D009135 Muscular Diseases pirinixic acid 3.8616239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2419151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1616411023
MESH:D009361 Neoplasm Invasiveness Curcumin 4.7018495463
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6419393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5919410462
MESH:D009369 Neoplasms pirinixic acid 2.0617405874
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 12.3712497104
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 12.3719189210 19196722 19200415
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.8817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5319348381 18481113
MESH:D009423 Nervous System Neoplasms Curcumin 6.0718462866
MESH:D009765 Obesity Curcumin 4.7919297423
MESH:D009765 Obesity pirinixic acid 4.7920558911
MESH:D010024 Osteoporosis Curcumin 3.6218719352
MESH:D010051 Ovarian Neoplasms Curcumin 2.8818462866 19020741
MESH:D010190 Pancreatic Neoplasms Curcumin 3.0119196508 17440100 19401701
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9911578682
MESH:D011230 Precancerous Conditions Cyclosporine 3.4712371664
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.2918220299 19015723 18042343
MESH:D011469 Prostatic Diseases vinclozolin 5.3318220299
MESH:D011471 Prostatic Neoplasms Curcumin 3.3310851300 12497104 18226269 11398177 15129424 18156803 18769126
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.3315067354
MESH:D011472 Prostatitis vinclozolin 5.3318629315
MESH:D011537 Pruritus Ethinyl Estradiol 3.7116919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.3016882103
MESH:D011656 Pulmonary Emphysema Curcumin 4.7919168576
MESH:D015427 Reperfusion Injury pirinixic acid 2.5019058328
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 4.3318379247 10666014
MESH:D012509 Sarcoma Curcumin 4.3818462866
MESH:D018805 Sepsis Curcumin 4.3118389075
MESH:D013088 Spermatocele Ethinyl Estradiol 13.0916709447
MESH:D013088 Spermatocele Tamoxifen 13.0916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.4319457130
MESH:D013276 Stomach Ulcer Curcumin 3.7716631530 19188055
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.9211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.4015669648
MESH:D001749 Urinary Bladder Neoplasms Curcumin 5.5618593936
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 5.5616712894 17572228 8653321
MESH:D014565 Urogenital Neoplasms Curcumin 5.6618462866
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.6314692618
MESH:D014605 Uveitis Cyclosporine 4.431336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.8214671159 15869587
MESH:D014985 Xerophthalmia Cyclosporine 4.8817120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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