AutismKB 2.0

Annotation Detail for TRAF4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TRAF4 ( CART1,MLN62,RNF83 )
Gene Full Name: TNF receptor-associated factor 4
Band: 17q11.2
Quick LinksEntrez ID:9618; OMIM: 602464; Uniprot ID:TRAF4_HUMAN; ENSEMBL ID: ENSG00000076604; HGNC ID: 12034
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05222Small cell lung cancer
hsa05200Pathways in cancer
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of TRAF4 mRNAaffects expression 21346803
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of TRAF4 mRNAincreases expression 16788091
C430898 AGN 194204 AGN 194204 results in decreased expression of TRAF4 mRNAdecreases expression 16339527
C006632 arsenic trioxide arsenic trioxide results in increased expression of TRAF4 mRNAincreases expression 17530438
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of TRAF4 mRNAincreases expression 20064835
D002117 Calcitriol Calcitriol results in increased expression of TRAF4 mRNAincreases expression 16002434
D004317 Doxorubicin Doxorubicin results in decreased expression of TRAF4 mRNAdecreases expression 16243910
D004391 Dust Dust results in increased expression of TRAF4 mRNAincreases expression 17805423
D004958 Estradiol Estradiol affects the expression of TRAF4 mRNAaffects expression 15598610
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of TRAF4 mRNAaffects expression 17555576
D005492 Folic Acid Folic Acid affects the expression of TRAF4 mRNAaffects expression 16361273
C031927 hydroquinone hydroquinone results in decreased expression of TRAF4 mRNAdecreases expression 15452088
D009151 Mustard Gas Mustard Gas results in increased expression of TRAF4 mRNAincreases expression 15674843
C006253 pirinixic acid pirinixic acid results in increased expression of TRAF4 mRNAincreases expression 18301758
D012643 Selenium [Selenium co-treated with Vitamin E] results in increased expression of TRAF4 mRNAaffects cotreatment|increases expression 19244175
D012643 Selenium Selenium results in increased expression of TRAF4 mRNAincreases expression 19244175
C017947 sodium arsenite sodium arsenite results in decreased expression of TRAF4 mRNAdecreases expression 19822182
D013629 Tamoxifen Tamoxifen affects the expression of TRAF4 mRNAaffects expression 17555576
C066075 vanadium pentoxide vanadium pentoxide results in decreased expression of TRAF4 mRNAdecreases expression 17459161
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in increased expression of TRAF4 mRNAaffects cotreatment|increases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.4914745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8917505938
MESH:D058186 Acute Kidney Injury Folic Acid 4.2717003819 16316344 16595132
MESH:D055371 Acute Lung Injury pirinixic acid 3.0518653653
MESH:D000230 Adenocarcinoma arsenic trioxide 13.3719825857 11798837
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 13.3720127859 20464547
MESH:D000230 Adenocarcinoma Doxorubicin 13.3717418594
MESH:D000230 Adenocarcinoma Estradiol 13.3711473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 13.3714692618
MESH:D000236 Adenoma Benzo(a)pyrene 6.856695378
MESH:D000236 Adenoma Folic Acid 6.8516963246
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.4216434500
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.6415276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.8517306315 16712894
MESH:D000419 Albuminuria Doxorubicin 4.4821441931
MESH:D000544 Alzheimer Disease Folic Acid 3.0317116317
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0119183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4011256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6215885639
MESH:D001249 Asthma Mustard Gas 2.6910378619
MESH:D001321 Autistic Disorder Folic Acid 2.8421388746
MESH:D001768 Blister Mustard Gas 5.1019167455
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.7916206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.7919483382
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.6414601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.7517150277
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.9417474063 20146248
MESH:D001943 Breast Neoplasms Calcitriol 2.9411237771
MESH:D001943 Breast Neoplasms Doxorubicin 2.9411325840 15567936 16115903 15136595 18628466 18234424 16096432 18382427 19526202 16826403 16264153 15993339 15939500 15994142 15634643 16935488 17369602 18695136 15692762 17426702 15668708 16322301 16595493 17983394
MESH:D001943 Breast Neoplasms Estradiol 2.9419861407 14630087 18497071 12948864 17018787 16675129 17289903 17261762
MESH:D001943 Breast Neoplasms Folic Acid 2.9416777985
MESH:D001943 Breast Neoplasms Tamoxifen 2.9419410462 20005174 20390343 18351453 19011961 18997820 21138602 11161223 19288272 20544844 17049068 17242785 16873071 15565566 15668708 19142967 17261762 19189212 19200415 18984771 17440819 20135344 19487384 19066611 21152245 20065188 20859285 16202921 16818667 19103187 19289846 19221464 18425577 18815881 19115204 17893378 19244106 19059307 18821012 18855134 19155303 19084267 16273361 18629630 19189210
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.1015286001
MESH:D001991 Bronchitis vanadium pentoxide 6.1817459161
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.9210378619 17687719
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2711589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4016111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8716050911
MESH:D002276 Carcinoid Tumor Doxorubicin 4.7516051944
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.4419066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 11.2616705839
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 11.2616217749 11135700 15073043 14691202 15553829
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 11.2618059187 16234567 17876044 16023760
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.2616924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 11.2617306315 15276417 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.2616924424
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.8219014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 3.1316201981 1485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0612490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 10.6620419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 10.6611237771
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 10.666189445
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 10.6618572023
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5517572228
MESH:D009202 Cardiomyopathies Doxorubicin 3.4816278810 17007740 16109756 17308081 17382496 16242529 15505089 16651473 17928571 17519947 16731534 17131338 16952015 16612575 15811867 18627295 15792986 17329180 17924179 15476868 16269455 16364871 17974986 17351982 16455267
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9217334414 16243910
MESH:D002318 Cardiovascular Diseases Folic Acid 3.9016755160
MESH:D002471 Cell Transformation, Neoplastic Estradiol 6.5918566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 6.5919524636 20056578
MESH:D002779 Cholestasis Ethinyl Estradiol 7.5815861022 17681005 17110522 16105132 16919318 11677210 17333356
MESH:D002779 Cholestasis pirinixic acid 7.5819176532
MESH:D002971 Cleft Lip Folic Acid 3.9421254359
MESH:D002972 Cleft Palate Folic Acid 3.5421254359 8946559
MESH:D003092 Colitis Selenium 3.7217936198
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.5420501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 3.5418802399 18259882
MESH:D015179 Colorectal Neoplasms Folic Acid 3.5417087956 17245555 16963246 17116713 16985020
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1212609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.6910525206
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.6919769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.9518551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0315213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.3019031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3918249437
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 3.1216886840
MESH:D003928 Diabetic Nephropathies Estradiol 8.6519279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 8.6519279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 6.2021346803 18551238
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 6.2017416283
MESH:D056486 Drug-Induced Liver Injury Selenium 6.2015131321
MESH:D004362 Drug Toxicity Doxorubicin 3.6218602426
MESH:C538011 Eales disease Vitamin E 4.659068938
MESH:D004487 Edema Mustard Gas 6.6811428631 9260866 11428647 11402378
MESH:D004487 Edema pirinixic acid 6.6812083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 14.9815138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 14.9812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 14.9819031437
MESH:D016889 Endometrial Neoplasms Doxorubicin 17.4717359293
MESH:D016889 Endometrial Neoplasms Estradiol 17.4718566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Folic Acid 17.4717301261
MESH:D016889 Endometrial Neoplasms Tamoxifen 17.4720544844 19155303 17893378 16202921
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.1018037988
MESH:D004890 Erythema Mustard Gas 5.109357497
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.3812903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.3816530937
MESH:D017889 Exfoliation Syndrome Folic Acid 5.4316504073
MESH:D005234 Fatty Liver arsenic trioxide 18.2515073043
MESH:D005234 Fatty Liver Ethinyl Estradiol 18.2515345470
MESH:D005234 Fatty Liver pirinixic acid 18.2519236843 20131406
MESH:D005234 Fatty Liver Tamoxifen 18.2519224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1916709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4714745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 11.2419069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 11.2419069698
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.2016904648
MESH:D005756 Gastritis Folic Acid 5.0317171786
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.6216452187
MESH:D005901 Glaucoma Folic Acid 5.0116504073
MESH:D005909 Glioblastoma Doxorubicin 3.3117150277
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.4815692506
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.1020471113
MESH:D006330 Heart Defects, Congenital Folic Acid 11.1016524890 17286298
MESH:D006330 Heart Defects, Congenital Vitamin E 11.1016080930
MESH:D006331 Heart Diseases Doxorubicin 3.4418006777 16879835 17875725 18674790 16330681 12587719 16144979 16495754 16244371 16244372 16707910 17888722 14766674
MESH:D006333 Heart Failure Doxorubicin 11.5717481944
MESH:D006333 Heart Failure pirinixic acid 11.5720558911
MESH:D006333 Heart Failure Selenium 11.5717162251
MESH:D006394 Hemangiosarcoma Doxorubicin 3.8415692506
MESH:D006529 Hepatomegaly pirinixic acid 2.9318467677 19176532 16221962 19772884
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6816863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 4.9815709030
MESH:D006679 HIV Seropositivity Folic Acid 5.4317209195
MESH:D006689 Hodgkin Disease Doxorubicin 7.2815147373 17606976 18501091
MESH:D006689 Hodgkin Disease sodium arsenite 7.2812676792
MESH:D019584 Hot Flashes Estradiol 9.8617088409
MESH:D019584 Hot Flashes Vitamin E 9.8614716179
MESH:D006943 Hyperglycemia pirinixic acid 3.1220558911
MESH:D020138 Hyperhomocysteinemia Folic Acid 4.4416397167 16865747 16433478 16755160 16395265
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7516569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4012013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.4917937319
MESH:D007248 Infertility, Male sodium arsenite 6.4915346721 12646999
MESH:D007249 Inflammation Mustard Gas 5.1211428631 17524151 11428620 9357497 16001271 8975870 9260866 11402378 11428647
MESH:D007249 Inflammation Tamoxifen 5.1219457130
MESH:D007251 Influenza, Human Selenium 10.7716624496
MESH:D007251 Influenza, Human Vitamin E 10.7716624496
MESH:D007333 Insulin Resistance Estradiol 7.0516627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 7.0516306350
MESH:D007674 Kidney Diseases Doxorubicin 14.1716775033 15369732 15699352
MESH:D007674 Kidney Diseases Estradiol 14.1715618244
MESH:D007674 Kidney Diseases sodium arsenite 14.1720008137
MESH:D007674 Kidney Diseases Vitamin E 14.1712488133
MESH:D007676 Kidney Failure, Chronic Doxorubicin 9.7816707910
MESH:D007676 Kidney Failure, Chronic Selenium 9.7816518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 12.0816705839
MESH:D007680 Kidney Neoplasms Estradiol 12.0815610895
MESH:D007680 Kidney Neoplasms Tamoxifen 12.0818625569
MESH:D007938 Leukemia arsenic trioxide 2.8015070760
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.1016085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.7317077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3814633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.7019077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1317050201 19850784 20471514 16467208 16968895
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.1717869043 19035177 12679006 9834237 15622746 12712474 19075265 17649720 16966277 17107899 11161223 11468182 19225113 19642359 15336539 15213294 16891316 16331271 16823087 16330433 16112521 15748426 17712046 12018890 17217047
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2916882451
MESH:D008064 Lipidoses Tamoxifen 3.1115342952 17567588
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 6.6516439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.6514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 6.6515474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 6.6518564211
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 6.6516169303
MESH:D008107 Liver Diseases Folic Acid 3.0316877991
MESH:D008113 Liver Neoplasms arsenic trioxide 13.9814682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 13.9821137059 20195826
MESH:D008113 Liver Neoplasms pirinixic acid 13.9820007298 16377806 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 13.9816712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 13.9816684651
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 6.0020377131
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 6.0017085340 16842330
MESH:D008133 Long QT Syndrome arsenic trioxide 3.3015213294
MESH:D008171 Lung Diseases Mustard Gas 12.1218702808 18161513
MESH:D008171 Lung Diseases sodium arsenite 12.1219095001
MESH:D008171 Lung Diseases Vitamin E 12.1216863852
MESH:D008175 Lung Neoplasms arsenic trioxide 12.8811798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 12.8820064080 18520028 6695378 18569708 20869020 20464547 20135361 17053015 18816296
MESH:D008175 Lung Neoplasms Doxorubicin 12.886189445 17418594
MESH:D008175 Lung Neoplasms Mustard Gas 12.883148597 8781369
MESH:D008175 Lung Neoplasms sodium arsenite 12.8815276417 17306315 17077188 16712894 19931552
MESH:D008175 Lung Neoplasms Tamoxifen 12.8818625569
MESH:D008175 Lung Neoplasms vanadium pentoxide 12.8812376484
MESH:D008175 Lung Neoplasms Vitamin E 12.8811062179
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.3217718048
MESH:D008223 Lymphoma Doxorubicin 3.4116098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.7317654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.5015621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.7019428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 13.9315458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 13.9317203775 11408345 16891317 11807958
MESH:D008325 Mammary Neoplasms, Experimental Selenium 13.9315318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 13.9316827153 19196722 19196723 11731420 14580682
MESH:D020149 Manganese Poisoning Estradiol 12.4619453300
MESH:D020149 Manganese Poisoning Tamoxifen 12.4619453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.6316832597
MESH:D008545 Melanoma Doxorubicin 5.0716827129
MESH:D008545 Melanoma sodium arsenite 5.0716487513 19082730
MESH:D008545 Melanoma Tamoxifen 5.0719393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.1215990972
MESH:D008654 Mesothelioma Doxorubicin 6.2017638057
MESH:D008654 Mesothelioma Selenium 6.2015107826
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.4415792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1416381670
MESH:D052016 Mucositis Doxorubicin 4.7317415656
MESH:D009101 Multiple Myeloma arsenic trioxide 3.0619549372 14977855 19417148 15949261 11468182
MESH:D009135 Muscular Diseases pirinixic acid 3.4416239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.6218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.1016882451 16105982
MESH:D009203 Myocardial Infarction Doxorubicin 5.6215857846 19429709
MESH:D009203 Myocardial Infarction pirinixic acid 5.6219151258
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.0816810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.0816411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.8018551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.9016624393
MESH:D009362 Neoplasm Metastasis Doxorubicin 5.7818259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.7819393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4919410462
MESH:D009369 Neoplasms Benzo(a)pyrene 8.0111141357
MESH:D009369 Neoplasms pirinixic acid 8.0117405874
MESH:D009369 Neoplasms sodium arsenite 8.0111559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.6020056578
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.9419196722 19189210 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6717289903
MESH:D009401 Nephrosis Doxorubicin 4.7016899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.9415640375 16889571
MESH:D009421 Nervous System Malformations Estradiol 3.5911399458 16427766
MESH:D009436 Neural Tube Defects arsenic trioxide 12.0310525206
MESH:D009436 Neural Tube Defects Folic Acid 12.0317438019
MESH:D009436 Neural Tube Defects sodium arsenite 12.0312854658
MESH:D009447 Neuroblastoma Doxorubicin 3.2315555623
MESH:D009503 Neutropenia Folic Acid 9.3916322990
MESH:D009503 Neutropenia Mustard Gas 9.3916761898 7688884
MESH:D009765 Obesity pirinixic acid 1.8020558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.3712819281 16049721
MESH:D012516 Osteosarcoma Doxorubicin 4.0615930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 7.7612452020 16624393 19769630
MESH:D010051 Ovarian Neoplasms Estradiol 7.7619401270
MESH:D010051 Ovarian Neoplasms sodium arsenite 7.7617306315 15276417
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.5015580305
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6211578682
MESH:D010235 Paraganglioma arsenic trioxide 4.1019927285
MESH:D003557 Phyllodes Tumor Doxorubicin 5.1017983394
MESH:D010954 Plasmacytoma Selenium 4.8315087411
MESH:D010997 Pleural Neoplasms Doxorubicin 5.1017638057
MESH:D011041 Poisoning Mustard Gas 3.7315727166
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.7215572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8220887781
MESH:D011471 Prostatic Neoplasms AGN 194204 2.9416000583
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.9419131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9417292933
MESH:D011471 Prostatic Neoplasms Calcitriol 2.9416289102 15754350 12479363 18247401 16644109
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.9416729912 18437689 16888761 15897917 16868541 15749863
MESH:D011471 Prostatic Neoplasms Estradiol 2.9416740699
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.9416039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.9415067354
MESH:D011471 Prostatic Neoplasms Vitamin E 2.9415084515
MESH:D011537 Pruritus Ethinyl Estradiol 9.3216919318 15861022
MESH:D011537 Pruritus Mustard Gas 9.3218058305
MESH:D011658 Pulmonary Fibrosis Mustard Gas 2.9017720292 17894541 17266442 17620002 10334151
MESH:D051437 Renal Insufficiency Doxorubicin 10.3017922066
MESH:D051437 Renal Insufficiency Folic Acid 10.3015728788
MESH:D015427 Reperfusion Injury pirinixic acid 2.3519058328
MESH:D012509 Sarcoma Doxorubicin 3.9318313854 16767912 17203757 15625365 15675481 17710206
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 10.0716646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 10.0714601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.7317846226
MESH:D012559 Schizophrenia Folic Acid 2.8916641680
MESH:D012640 Seizures 2,4-dinitrotoluene 2.4918551238
MESH:D012871 Skin Diseases Folic Acid 7.9818709164
MESH:D012871 Skin Diseases Mustard Gas 7.9816961503 12880345 15451306
MESH:D012871 Skin Diseases Vitamin E 7.9818709164
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.3410029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 9.3415692506
MESH:D012878 Skin Neoplasms sodium arsenite 9.3418572023 19524636
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.5016767912 17203757 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 11.3716709447
MESH:D013088 Spermatocele Tamoxifen 11.3716709447
MESH:D013118 Spinal Cord Diseases Folic Acid 5.4316361298
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.9819457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.7412854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 3.4317007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.4320155912 2093021
MESH:D013274 Stomach Neoplasms Folic Acid 3.4317171786
MESH:D020521 Stroke Folic Acid 8.7216517955
MESH:D020521 Stroke Vitamin E 8.7216517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5611994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0915669648
MESH:D013964 Thyroid Neoplasms arsenic trioxide 7.1619014326
MESH:D013964 Thyroid Neoplasms Doxorubicin 7.1616010429 17909728
MESH:D013978 Tibial Fractures Estradiol 4.6319048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.9015213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 19.5616049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 19.5611780464 20435036 12845720 12973940
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 19.5617053015
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 19.5617653716
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 19.5616712894 11723127 16452187 17306315
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 19.568653321 17572228 16712894
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.2510091137
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.7111813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2314692618
MESH:D014652 Vascular Diseases sodium arsenite 4.3617056641
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4814671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.1617678736 16364871 17638931 17334414
Pathway ID Pathway Name
KEGG:05200 Pathways in cancer
KEGG:05222 Small cell lung cancer
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved