AutismKB 2.0

Annotation Detail for FNIP1


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Basic Information Top
Gene Symbol:FNIP1 ( DKFZp686E18167,DKFZp781P0215,KIAA1961,MGC667 )
Gene Full Name: folliculin interacting protein 1
Band: 5q31.1
Quick LinksEntrez ID:96459; OMIM: 610594; Uniprot ID:FNIP1_HUMAN; ENSEMBL ID: ENSG00000217128; HGNC ID: 29418
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of FNIP1 mRNAaffects expression 17562736
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of FNIP1 mRNAaffects expression 17331233
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of FNIP1 mRNAincreases expression 18687144
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of FNIP1 mRNAdecreases expression 19150397
D016572 Cyclosporine Cyclosporine results in increased expression of FNIP1 mRNAincreases expression 20106945
D004041 Dietary Fats Dietary Fats results in increased expression of FNIP1 mRNAincreases expression 18042831
C041786 palm oil palm oil results in increased expression of FNIP1 mRNAincreases expression 18042831
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.3610982225
MESH:D001161 Arteriosclerosis Dietary Fats 4.3115238619
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Dietary Fats 2.2520435547
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.403084413
MESH:D002386 Cataract Acetaminophen 2.7510977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.2620889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.2612371664
MESH:D002779 Cholestasis Cyclosporine 3.1419486331
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6510915739 14550746 17522070 17562736 12958197 10663392 16781746 15619225 17906064 19370779 18071297 11529661 15968718 16393943 11461765 12392966 12705907 11743745 19739265 12540782 14725611 10774834 11287661 12153990 16081117 19420014 11421492 11739529 16177239 16485898 19085960 18713872 19416960 14986274 16109766 16227642 11834606 19164858 2444490 19923254 12594235
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.6219426721
MESH:D050171 Dyslipidemias Dietary Fats 3.6718367378
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1320426865
MESH:D005234 Fatty Liver Cyclosporine 8.8419224547
MESH:D005234 Fatty Liver Dietary Fats 8.8417967931 19004024 19551842 18296743
MESH:D005355 Fibrosis Cyclosporine 10.1212639820 12168785
MESH:D005355 Fibrosis Dietary Fats 10.1218296743
MESH:D005756 Gastritis Acetaminophen 4.1916983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.688708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8815720958
MESH:D006930 Hyperalgesia Acetaminophen 2.9516870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.9221332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.9721332399
MESH:D006973 Hypertension Cyclosporine 2.1910903974
MESH:D007249 Inflammation Dietary Fats 2.5720412841
MESH:D007333 Insulin Resistance Dietary Fats 3.3018457598 11836018
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.9615604871
MESH:D007674 Kidney Diseases Acetaminophen 6.3412587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 6.3410903974 8314463 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0012371664
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0318296743
MESH:D008107 Liver Diseases Acetaminophen 1.6919784758 16610002 11587558 16611625 12587719 12969438 19460945 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5416871587 17185352
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.4417365036
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9819513568
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.2816966607 18303189 16166281
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.3116801185
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.9617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5719348381 18481113
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1418514411
MESH:D009765 Obesity Dietary Fats 2.3420132043 21332399 11836018 17217161 20518802 18674790 16723640 19632207 18457598
MESH:D010146 Pain Acetaminophen 2.6516870215
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.3110923243
MESH:D011230 Precancerous Conditions Cyclosporine 3.5112371664
MESH:D011565 Psoriasis Cyclosporine 2.3116882103
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.1317365031 17975199 17322281 15814490
MESH:D014581 Urticaria Acetaminophen 3.3310982225
MESH:D014605 Uveitis Cyclosporine 4.501336536
MESH:D015430 Weight Gain Dietary Fats 4.0216723640
MESH:D014985 Xerophthalmia Cyclosporine 4.9617120751
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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