Annotation Detail for PPM1F
Basic Information Top
| Gene Symbol: | PPM1F ( CAMKP,CaMKPase,FEM-2,KIAA0015,POPX2,hFEM-2 ) |
|---|---|
| Gene Full Name: | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| Band: | 22q11.22 |
| Quick Links | Entrez ID:9647; OMIM: NA; Uniprot ID:PPM1F_HUMAN; ENSEMBL ID: ENSG00000100034; HGNC ID: 19388 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| No data |
| No data |
| Desease Name |
|---|
| ADHD |
| PSYCH |
| attention-deficit hyperactivity disorder |
| Desease Name |
|---|
| Attention deficit hyperactivity disorder |
| No data |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of PPM1F mRNA | affects expression | 16483693 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in increased expression of PPM1F mRNA | increases expression | 19152381 |
| D001564 | Benzo(a)pyrene | chlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of PPM1F mRNA] | decreases reaction|increases expression | 19152381 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride affects the expression of PPM1F mRNA | affects expression | 12734012 |
| C007020 | chlorophyllin | chlorophyllin inhibits the reaction [Benzo(a)pyrene results in increased expression of PPM1F mRNA] | decreases reaction|increases expression | 19152381 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000138 | Acidosis | Ammonium Chloride | 4.19 | 18287403 | |
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 2.06 | 20127859 20464547 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 2.86 | 6695378 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 4.64 | 19183758 | |
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 1.99 | 20146248 17474063 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 4.34 | 16124888 15673190 16192424 15721981 16097048 10355542 3786805 15700767 18705752 16227642 16050911 16011737 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 1.86 | 18788625 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 2.13 | 20419170 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 2.12 | 16227642 10092053 10915739 15027814 3786805 7179309 7120509 15998439 21278145 11566570 3732212 6623471 9327722 19336974 16177239 2869522 4309450 6884620 15968718 19085960 7440962 17522070 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 2.08 | 16530937 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 3.59 | 16239168 12631006 17595544 19224547 15959796 16045604 12795759 61145 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 4.01 | 18705752 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 2.83 | 20471113 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 4.10 | 19900420 19110552 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 5.16 | 16899240 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 4.65 | 15338365 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 3.00 | 17174718 17157831 16943688 11903743 11408273 16239168 16221502 21278145 17334410 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 1.75 | 18339082 15931870 17525996 11481614 17714472 12546737 18156304 18277467 18412020 18481824 17976157 15673190 17640975 18472094 18420326 12649538 15818738 16136751 12667390 16116963 18376398 14620537 16033810 15925388 17631135 17698563 18418968 17869086 14716833 18472332 12586293 18317297 15996030 17823541 18395914 17557913 18279442 15650968 15876570 14748882 12445421 15057751 16011737 14512876 17721639 16015684 18251166 17944888 15959796 12666154 17900296 15338365 13678700 12632514 15052691 12898905 12609069 17481882 12741479 12445418 18187930 16248980 16027843 17761835 12632512 18054572 15362042 18166357 18205269 15893842 12958196 18006644 16192424 18705752 16097048 17922224 18263696 18210741 18429990 14716496 17766677 14724832 15123356 17708605 18395095 17805973 10355542 17565644 16638106 15370692 12389079 15730626 20821823 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 2.15 | 16246199 15830285 15720792 16964402 17285989 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 4.73 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 4.08 | 14706259 16899240 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 4.92 | 21137059 20195826 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 4.92 | 19294768 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 2.84 | 15583823 12014681 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 1.57 | 18816296 17053015 18569708 20869020 18520028 20135361 20464547 20064080 6695378 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 3.50 | 16381670 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 2.33 | 11141357 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 2.91 | 17292933 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 2.52 | 19755658 10029692 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 1.56 | 2093021 20155912 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 2.30 | 17053015 |
| No data |