Annotation Detail for CEP135
Basic Information
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| Pathway ID | Pathway Name |
|---|
| Cell Cycle, Mitotic |
| Pathway ID | Pathway Name |
|---|
| 500383 | Loss of proteins required for interphase microtubule organization from the centrosome |
| 500384 | Loss of Nlp from mitotic centrosomes |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D003010 |
Clorgyline |
Clorgyline results in increased expression of CEP135 mRNA | increases expression | 19691856
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CEP135 mRNA | affects binding|decreases expression|increases activity | 19710929
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.72 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.37 | 16434500 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.70 | 19483382 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.19 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.61 | 18249437 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
3.02 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.31 | 19236843 20131406 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.81 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.76 | 18467677 19772884 19176532 16221962 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.69 | 20558911 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.93 | 16306350 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.95 | 15890375 16377806 20007298 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.27 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.30 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.33 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.14 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.90 | 20558911 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Clorgyline |
4.22 | 19691856 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.58 | 19058328 |
| Pathway ID |
Pathway Name |
|---|
| REACT:152 |
Cell Cycle, Mitotic |
PharmGKB Accession:PA128394551
| Releated disease ID |
Related disease Name |
| PA446155 | Precursor Cell Lymphoblastic Leukemia-Lymphoma |
Related Diseases/Disorders