AutismKB 2.0

Annotation Detail for UBE3C


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Basic Information Top
Gene Symbol:UBE3C ( KIAA0010,KIAA10 )
Gene Full Name: ubiquitin protein ligase E3C
Band: 7q36.3
Quick LinksEntrez ID:9690; OMIM: NA; Uniprot ID:UBE3C_HUMAN; ENSEMBL ID: ENSG00000009335; HGNC ID: 16803
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
hsa04120Ubiquitin mediated proteolysis
Related Diseases/Disorders Top
Desease Name
PHARMACOGENOMIC
response to citalopram treatment
quantitative traits
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in increased expression of UBE3C mRNAincreases expression 20406850
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of UBE3C mRNAdecreases expression 19150397
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of UBE3C mRNAdecreases expression 15336504
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of UBE3C mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBE3C mRNAaffects cotreatment|increases expression 17942748
C006253 pirinixic acid pirinixic acid results in increased expression of UBE3C mRNAincreases expression 18301758
D020849 Raloxifene Raloxifene results in decreased expression of UBE3C mRNAdecreases expression 19429434
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBE3C mRNAaffects cotreatment|increases expression 17942748
Pharmacogenomics Knowledge Base Top
Drug Bank Top

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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