Annotation Detail for CROCC
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C014347 |
decitabine |
decitabine results in increased expression of CROCC mRNA | increases expression | 19194470
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CROCC mRNA | affects binding|decreases expression|increases activity | 19710929
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.72 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.37 | 16434500 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.70 | 19483382 |
| MESH:D001943 |
Breast Neoplasms |
|
decitabine |
2.53 | 19208741 18320071 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
decitabine |
2.69 | 19215824 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.19 | 19176532 |
| MESH:D003110 |
Colonic Neoplasms |
|
decitabine |
2.39 | 17616700 |
| MESH:D015179 |
Colorectal Neoplasms |
|
decitabine |
2.11 | 18981723 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.61 | 18249437 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
3.02 | 12083418 |
| MESH:D004701 |
Endocrine Gland Neoplasms |
|
decitabine |
6.19 | 19294695 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.31 | 20131406 19236843 |
| MESH:D006258 |
Head and Neck Neoplasms |
|
decitabine |
3.80 | 19215824 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.81 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.76 | 19176532 16221962 18467677 19772884 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.69 | 20558911 |
| MESH:D007248 |
Infertility, Male |
|
decitabine |
3.51 | 17581917 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.93 | 16306350 |
| MESH:D007938 |
Leukemia |
|
decitabine |
3.27 | 18980019 19235587 |
| MESH:D007951 |
Leukemia, Myeloid |
|
decitabine |
4.55 | 17236224 18454857 19117987 |
| MESH:D015470 |
Leukemia, Myeloid, Acute |
|
decitabine |
2.44 | 18460780 18206229 17679729 19387464 19010910 18704418 |
| MESH:D015477 |
Leukemia, Myelomonocytic, Chronic |
|
decitabine |
6.53 | 18055864 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.95 | 15890375 16377806 20007298 |
| MESH:D008223 |
Lymphoma |
|
decitabine |
3.76 | 19470736 |
| MESH:D008545 |
Melanoma |
|
decitabine |
2.29 | 16505122 17785578 |
| MESH:D009101 |
Multiple Myeloma |
|
decitabine |
3.69 | 18172295 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.27 | 16239165 |
| MESH:D009190 |
Myelodysplastic Syndromes |
|
decitabine |
3.62 | 19010910 16882708 18608210 19157545 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.30 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.33 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
decitabine |
5.70 | 19116145 17925555 19470736 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
5.70 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.90 | 20558911 |
| MESH:D010051 |
Ovarian Neoplasms |
|
decitabine |
2.76 | 19331143 19259094 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
decitabine |
2.90 | 19294695 |
| MESH:D055728 |
Primary Myelofibrosis |
|
decitabine |
5.49 | 17616702 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.58 | 19058328 |
| MESH:D012208 |
Rhabdomyosarcoma |
|
decitabine |
5.01 | 19155313 |
| MESH:D013274 |
Stomach Neoplasms |
|
decitabine |
2.11 | 19037991 |
| MESH:D013964 |
Thyroid Neoplasms |
|
decitabine |
3.71 | 17967635 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
decitabine |
2.86 | 17616700 19087683 |
| MESH:D014604 |
Uveal Neoplasms |
|
decitabine |
5.98 | 17785578 |
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