AutismKB 2.0

Annotation Detail for CD79A


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Basic Information Top
Gene Symbol:CD79A ( IGA,MB-1 )
Gene Full Name: CD79a molecule, immunoglobulin-associated alpha
Band: 19q13.2
Quick LinksEntrez ID:973; OMIM: 112205; Uniprot ID:CD79A_HUMAN; ENSEMBL ID: ENSG00000105369; HGNC ID: 1698
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05340Primary immunodeficiency
hsa04662B cell receptor signaling pathway
No data
Pathway IDPathway Name
200005BCR signaling pathway
Pathway IDPathway Name
P00010B cell activation
No data
Related Diseases/Disorders Top
Desease IDDesease Name
H00085Agammaglobulinemias
Immune system diseases
Primary immunodeficiency
No data
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C061133 Am 80 Am 80 results in increased expression of CD79A mRNAincreases expression 17229644
D002330 Carmustine Carmustine results in decreased expression of CD79A mRNAdecreases expression 15980968
D005419 Flavonoids Flavonoids results in decreased expression of CD79A mRNAdecreases expression 15465739
D010126 Ozone Ozone results in decreased expression of CD79A mRNAdecreases expression 12763052
C006253 pirinixic acid pirinixic acid results in decreased expression of CD79A mRNAdecreases expression 17426115
D010936 Plant Extracts Plant Extracts results in decreased expression of CD79A mRNAdecreases expression 15465739
C025299 polyphenols polyphenols results in decreased expression of CD79A mRNAdecreases expression 15465739
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in increased expression of CD79A mRNAincreases expression 17982090
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.3818653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.8216434500
MESH:D000544 Alzheimer Disease Ozone 4.7015513908
MESH:D000544 Alzheimer Disease Plant Extracts 4.7016962711
MESH:D001169 Arthritis, Experimental Plant Extracts 4.0814686799
MESH:D001172 Arthritis, Rheumatoid Am 80 5.3816819260
MESH:D001172 Arthritis, Rheumatoid Ozone 5.3815570426
MESH:D001249 Asthma Ozone 2.7017854713 16373670
MESH:D050197 Atherosclerosis Am 80 4.4716484594
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.3919483382
MESH:D002545 Brain Ischemia Plant Extracts 5.0616041641
MESH:D001932 Brain Neoplasms Carmustine 4.6116187019
MESH:D016535 Bronchial Hyperreactivity Ozone 3.8714754758 16777450 17626835 15516495 19059883 18315731 18417511
MESH:D002057 Burns, Chemical Plant Extracts 5.719625245
MESH:D002100 Cachexia Ozone 5.0816183385
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 2.7818834353
MESH:D006332 Cardiomegaly Plant Extracts 3.9217645561
MESH:D002779 Cholestasis pirinixic acid 3.0019176532
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 4.8516867261 16804969 18200517 11698051 17991707 16782535 17936198 18023891 16474422
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.5117276891
MESH:D003110 Colonic Neoplasms polyphenols 2.7016293270
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5218249437
MESH:D003928 Diabetic Nephropathies Plant Extracts 4.6219706694
MESH:D056486 Drug-Induced Liver Injury polyphenols 2.7919370779
MESH:D004487 Edema pirinixic acid 7.8812083418
MESH:D004487 Edema Plant Extracts 7.8812787963
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Am 80 5.3716819260
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 6.0615268973
MESH:D004827 Epilepsy Plant Extracts 3.8419439326 19700373
MESH:D005234 Fatty Liver pirinixic acid 8.8319236843 20131406
MESH:D005234 Fatty Liver Plant Extracts 8.8315975614
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 4.6617994277
MESH:D005909 Glioblastoma Carmustine 4.0716187019
MESH:D006333 Heart Failure pirinixic acid 7.7020558911
MESH:D006333 Heart Failure Plant Extracts 7.7018097624
MESH:D006529 Hepatomegaly pirinixic acid 3.3018467677 16221962 19772884 19176532
MESH:D006561 Herpes Simplex Plant Extracts 4.9610715843
MESH:D015658 HIV Infections Plant Extracts 3.7912878215
MESH:D019584 Hot Flashes Plant Extracts 5.1214716179 17454163 16566672
MESH:D006943 Hyperglycemia pirinixic acid 3.4120558911
MESH:D020138 Hyperhomocysteinemia Plant Extracts 4.6816484555
MESH:D006949 Hyperlipidemias Plant Extracts 4.7315268973 15975614
MESH:D007249 Inflammation Flavonoids 9.2617296493
MESH:D007249 Inflammation Plant Extracts 9.2616366677 12787963 15997105 19332304
MESH:D007249 Inflammation polyphenols 9.2616366677
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 3.6618200517
MESH:D007333 Insulin Resistance pirinixic acid 2.7816306350
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 4.9117994277
MESH:D007414 Intestinal Neoplasms Plant Extracts 4.8412628509 12351151 12584176
MESH:D015473 Leukemia, Promyelocytic, Acute Am 80 4.7916819260 16531727
MESH:D008103 Liver Cirrhosis Plant Extracts 3.8517157831
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.7215474484
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 2.7215479170
MESH:D008107 Liver Diseases Plant Extracts 4.8417034775
MESH:D008107 Liver Diseases polyphenols 4.8416698588
MESH:D008113 Liver Neoplasms pirinixic acid 5.0316377806 20007298 15890375
MESH:D008113 Liver Neoplasms Plant Extracts 5.0319168119
MESH:D008171 Lung Diseases Ozone 3.5319066396 8266340
MESH:D055370 Lung Injury Ozone 4.1520417186
MESH:D008175 Lung Neoplasms Ozone 2.967614698 8597069
MESH:D008175 Lung Neoplasms Plant Extracts 2.9620869020
MESH:D008545 Melanoma Carmustine 2.8912393984
MESH:D008679 Metaplasia Ozone 5.4810496685
MESH:D009101 Multiple Myeloma Am 80 4.7017229644
MESH:D009135 Muscular Diseases pirinixic acid 3.8116239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2219151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1316411023
MESH:D009369 Neoplasms pirinixic acid 2.0517405874
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 5.4917168769
MESH:D009765 Obesity pirinixic acid 4.9220558911
MESH:D009765 Obesity Plant Extracts 4.9219056576 20132043
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 4.4617698068
MESH:D010212 Papilloma Plant Extracts 4.8016517061 15173996
MESH:D010538 Peritonitis Ozone 4.4416369182
MESH:D011014 Pneumonia Ozone 4.7318929643 18007984 18381685
MESH:D011471 Prostatic Neoplasms Am 80 4.0616289102
MESH:D011471 Prostatic Neoplasms Plant Extracts 4.0614666653 17804756
MESH:D011565 Psoriasis Am 80 4.1616819260
MESH:D015427 Reperfusion Injury pirinixic acid 2.4919058328
MESH:D012878 Skin Neoplasms Plant Extracts 3.5716517061 15173996
MESH:D013276 Stomach Ulcer Plant Extracts 4.1318237397 18193104 12787963 15255614 17135157
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 14.5617997062
MESH:D013705 Temporomandibular Joint Disorders polyphenols 14.5617997062
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 5.0518097624
MESH:D020257 Ventricular Remodeling Plant Extracts 5.6518097624
MESH:D014947 Wounds and Injuries Plant Extracts 4.4520213670 19894650
Pathway ID Pathway Name
KEGG:04662 B cell receptor signaling pathway
KEGG:05340 Primary immunodeficiency
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26237
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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