AutismKB 2.0

Annotation Detail for SETD1A


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Basic Information Top
Gene Symbol:SETD1A ( KIAA0339,KMT2F,Set1,Set1A )
Gene Full Name: SET domain containing 1A
Band: 16p11.2
Quick LinksEntrez ID:9739; OMIM: 611052; Uniprot ID:SET1A_HUMAN; ENSEMBL ID: ENSG00000099381; HGNC ID: 29010
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of SETD1A mRNAaffects expression 17562736
C006780 bisphenol A bisphenol A results in decreased expression of SETD1A mRNAdecreases expression 15223131
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D001862 Bone Resorption bisphenol A 4.4111985600
MESH:D001943 Breast Neoplasms bisphenol A 2.4217123778
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002278 Carcinoma in Situ bisphenol A 5.8817123778
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6814725611 12594235 12540782 15968718 10915739 12392966 17906064 19164858 14986274 16081117 11287661 16109766 19739265 19420014 11421492 11834606 12958197 16227642 16781746 16485898 17522070 17562736 18071297 10663392 11529661 11743745 11461765 11739529 12705907 19923254 19416960 2444490 14550746 19370779 16393943 19085960 18713872 10774834 12153990 16177239 15619225
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007333 Insulin Resistance bisphenol A 3.5816393666
MESH:D007674 Kidney Diseases Acetaminophen 2.4415629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7119014921 12969438 19784758 12587719 19460945 11587558 16610002 16611625
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7417185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D009421 Nervous System Malformations bisphenol A 4.6511399458 16427766
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D010049 Ovarian Diseases bisphenol A 5.8811985600
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 4.8410548101
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.7620887781
MESH:D011471 Prostatic Neoplasms bisphenol A 3.3316740699
MESH:D011629 Puberty, Precocious bisphenol A 5.6710548101
MESH:D019966 Substance-Related Disorders bisphenol A 4.8716684133 16045194
MESH:D014581 Urticaria Acetaminophen 3.5810982225
MESH:D014591 Uterine Diseases bisphenol A 6.0814652134
Pathway ID Pathway Name
KEGG:00310 Lysine degradation
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA128394556
  • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

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    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018