Annotation Detail for MLL4
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C472791 |
3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid |
3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of MLL4 mRNA | increases expression | 12958071
|
| D017638 |
Asbestos, Crocidolite |
Asbestos, Crocidolite affects the expression of MLL4 mRNA | affects expression | 17331233
|
| D008628 |
Mercury |
Mercury results in increased expression of MLL4 mRNA | increases expression | 16823088
|
| D012643 |
Selenium |
[Selenium co-treated with Vitamin E] results in increased expression of MLL4 mRNA | affects cotreatment|increases expression | 19244175
|
| D012643 |
Selenium |
Selenium results in increased expression of MLL4 mRNA | increases expression | 19244175
|
| D014810 |
Vitamin E |
[Selenium co-treated with Vitamin E] results in increased expression of MLL4 mRNA | affects cotreatment|increases expression | 19244175
|
| D014810 |
Vitamin E |
Vitamin E results in increased expression of MLL4 mRNA | increases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D001321 |
Autistic Disorder |
|
Mercury |
2.76 | 17497416 |
| MESH:D001327 |
Autoimmune Diseases |
|
Mercury |
5.36 | 16634805 |
| MESH:D002252 |
Carbon Tetrachloride Poisoning |
|
Vitamin E |
4.41 | 16050911 |
| MESH:D002311 |
Cardiomyopathy, Dilated |
|
Mercury |
3.55 | 10334427 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.26 | 17936198 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Vitamin E |
1.92 | 19769572 |
| MESH:D017449 |
Dermatitis, Allergic Contact |
|
Mercury |
4.27 | 16823706 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
2.25 | 15131321 |
| MESH:C538011 |
Eales disease |
|
Vitamin E |
5.32 | 9068938 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Vitamin E |
3.15 | 16080930 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
3.27 | 17162251 |
| MESH:D006548 |
Hernia, Diaphragmatic |
|
Vitamin E |
2.80 | 16490937 16863852 |
| MESH:D019584 |
Hot Flashes |
|
Vitamin E |
4.58 | 14716179 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
13.09 | 16624496 |
| MESH:D007251 |
Influenza, Human |
|
Vitamin E |
13.09 | 16624496 |
| MESH:D007674 |
Kidney Diseases |
|
Mercury |
7.08 | 17934191 |
| MESH:D007674 |
Kidney Diseases |
|
Vitamin E |
7.08 | 12488133 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.26 | 16518626 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Vitamin E |
1.90 | 16169303 |
| MESH:D008171 |
Lung Diseases |
|
Vitamin E |
3.40 | 16863852 |
| MESH:D055370 |
Lung Injury |
|
Asbestos, Crocidolite |
4.50 | 17365036 |
| MESH:D008175 |
Lung Neoplasms |
|
Vitamin E |
1.90 | 11062179 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
2.97 | 15318939 |
| MESH:D008654 |
Mesothelioma |
|
Asbestos, Crocidolite |
6.72 | 18303189 16966607 16166281 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
6.72 | 15107826 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.50 | 15087411 |
| MESH:D010995 |
Pleural Diseases |
|
Asbestos, Crocidolite |
5.38 | 10923243 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Vitamin E |
3.25 | 15084515 |
| MESH:D011658 |
Pulmonary Fibrosis |
|
Asbestos, Crocidolite |
3.14 | 17365031 17975199 17322281 15814490 |
| MESH:D012871 |
Skin Diseases |
|
Vitamin E |
2.51 | 18709164 |
| MESH:D020521 |
Stroke |
|
Vitamin E |
3.81 | 16517955 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:00310 |
Lysine degradation |
Related Pathway Information