AutismKB 2.0

Annotation Detail for RIMS3


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Basic Information Top
Gene Symbol:RIMS3 ( KIAA0237,NIM3,RIM3 )
Gene Full Name: regulating synaptic membrane exocytosis 3
Band: 1p34.2
Quick LinksEntrez ID:9783; OMIM: 611600; Uniprot ID:RIMS3_HUMAN; ENSEMBL ID: ENSG00000117016; HGNC ID: 21292
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RIMS3 mRNAaffects expression 16483693
D001554 Benzene Benzene affects the expression of RIMS3 mRNAaffects expression 15878777
D005419 Flavonoids Flavonoids results in increased expression of RIMS3 mRNAincreases expression 18035473
C008493 methylselenic acid methylselenic acid results in increased expression of RIMS3 mRNAincreases expression 18548127
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of RIMS3 mRNAaffects binding|decreases expression|increases activity 19710929
C034028 vanadyl sulfate vanadyl sulfate results in decreased expression of RIMS3 mRNAdecreases expression 16330358
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.0218287403
MESH:D055371 Acute Lung Injury pirinixic acid 3.4718653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.9416434500
MESH:D000741 Anemia, Aplastic Benzene 4.6111369114 14761424 17661222
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.4719483382
MESH:D001855 Bone Marrow Diseases Benzene 5.7516183116
MESH:D001943 Breast Neoplasms Benzene 2.8611921183 17162533
MESH:D002779 Cholestasis pirinixic acid 3.0519176532
MESH:D019465 Craniofacial Abnormalities Benzene 2.4515643154
MESH:D003872 Dermatitis Benzene 5.1815902427
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5518249437
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 4.6416684804
MESH:D004487 Edema pirinixic acid 2.8012083418
MESH:D005234 Fatty Liver pirinixic acid 3.0919236843 20131406
MESH:D006333 Heart Failure pirinixic acid 2.7120558911
MESH:D006402 Hematologic Diseases Benzene 5.0116183116
MESH:D006529 Hepatomegaly pirinixic acid 3.4116221962 18467677 19176532 19772884
MESH:D006943 Hyperglycemia pirinixic acid 3.4920558911
MESH:D006973 Hypertension Benzene 3.1817940673
MESH:D007249 Inflammation Flavonoids 2.7917296493
MESH:D007333 Insulin Resistance pirinixic acid 2.8216306350
MESH:D007938 Leukemia Benzene 3.5217119257 18335105 15935818 14694614
MESH:D007951 Leukemia, Myeloid Benzene 4.6417506065
MESH:D015470 Leukemia, Myeloid, Acute Benzene 2.7419478238
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 1.9115890375 20007298 16377806
MESH:D008114 Liver Neoplasms, Experimental Benzene 3.4712562636
MESH:D017563 Lung Diseases, Interstitial Benzene 5.3314698565
MESH:D008175 Lung Neoplasms Benzene 2.4312562636
MESH:D008223 Lymphoma Benzene 3.9517119257 17584886
MESH:D015674 Mammary Neoplasms, Animal Benzene 4.9012562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 3.4911921183
MESH:D009101 Multiple Myeloma Benzene 3.8817119195
MESH:D009135 Muscular Diseases pirinixic acid 3.9216239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2519151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1916411023
MESH:D009369 Neoplasms pirinixic acid 2.0817405874
MESH:D009436 Neural Tube Defects Benzene 3.8615643154
MESH:D009765 Obesity pirinixic acid 1.8720558911
MESH:D009784 Occupational Diseases Benzene 4.4816737584 17119257 15913788 15612468 15935809 17479406 17178637 15727169 15576619
MESH:D010051 Ovarian Neoplasms Benzene 3.0412562636
MESH:D011471 Prostatic Neoplasms methylselenic acid 3.8416205645
MESH:D015427 Reperfusion Injury pirinixic acid 2.5219058328
MESH:D013274 Stomach Neoplasms Benzene 2.4212562636
MESH:D013953 Thymus Neoplasms Benzene 5.4210850423
MESH:D014594 Uterine Neoplasms Benzene 4.7112562636
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018