AutismKB 2.0

Annotation Detail for MTSS1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MTSS1 ( DKFZp781P2223,FLJ44694,KIAA0429,MIM,MIMA,MIMB )
Gene Full Name: metastasis suppressor 1
Band: 8q24.13
Quick LinksEntrez ID:9788; OMIM: 608486; Uniprot ID:MTSS1_HUMAN; ENSEMBL ID: ENSG00000170873; HGNC ID: 20443
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200147Hedgehog signaling events mediated by Gli proteins
No data
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Related Diseases/Disorders Top
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Desease IDDesease Name
2022Liver cancer
2125Bladder cancer
2237Neoplasm metastasis
No data
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of MTSS1 mRNAincreases expression 18648102
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of MTSS1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of MTSS1 mRNAaffects expression 17562736
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of MTSS1 mRNAdecreases expression 20064835
D016572 Cyclosporine Cyclosporine results in decreased expression of MTSS1 mRNAdecreases expression 20106945
C014347 decitabine decitabine affects the methylation of MTSS1 promoteraffects methylation 16921485
C014347 decitabine [decitabine affects the methylation of MTSS1 promoter] which affects the expression of MTSS1 mRNAaffects expression|affects methylation 16921485
C014347 decitabine decitabine results in increased expression of MTSS1 mRNAincreases expression 16367923
D002117 Calcitriol Calcitriol results in increased expression of MTSS1 mRNAincreases expression 16002434
D004317 Doxorubicin MTSS1 mRNA affects the susceptibility to Doxorubicinaffects response to substance 16243817
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of MTSS1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of MTSS1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MTSS1 mRNAaffects cotreatment|increases expression 17942748
C029938 nickel sulfate nickel sulfate results in increased expression of MTSS1 mRNAincreases expression 16780908
D010634 Phenobarbital Phenobarbital results in decreased expression of MTSS1 mRNAdecreases expression 19270015
C410733 scriptaid scriptaid affects the expression of MTSS1 mRNAaffects expression 18813790
D013629 Tamoxifen Tamoxifen affects the expression of MTSS1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MTSS1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of MTSS1 mRNAdecreases expression 18691609
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6414745880
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 14.767525203
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 14.766195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 14.7614514962 15322242 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0417505938
MESH:D055371 Acute Lung Injury nickel sulfate 4.3712718980 16100012 19131640 11954676
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 7.1420464547 20127859
MESH:D000230 Adenocarcinoma Doxorubicin 7.1417418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 7.1414692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.703712494
MESH:D000236 Adenoma Benzo(a)pyrene 6.706695378
MESH:D018248 Adenoma, Liver Cell Phenobarbital 10.3617620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.3616835633
MESH:D000419 Albuminuria Doxorubicin 4.6121441931
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0011748828
MESH:D000799 Angioedema Acetaminophen 3.9410982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1519183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6915885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.1211289319 1440618
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.1012125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8015746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.8014601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.8617150277
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.9817474063 20146248
MESH:D001943 Breast Neoplasms Calcitriol 2.9811237771
MESH:D001943 Breast Neoplasms decitabine 2.9819208741 18320071
MESH:D001943 Breast Neoplasms Doxorubicin 2.9816264153 15567936 16595493 17983394 18695136 18382427 19526202 15994142 15136595 15668708 15939500 11325840 18628466 17369602 16096432 17426702 16322301 16935488 15634643 16115903 16826403 18234424 15692762 15993339
MESH:D001943 Breast Neoplasms Tamoxifen 2.9817893378 17440819 19155303 19487384 19189210 16202921 18351453 19059307 20135344 18821012 19189212 19142967 17261762 19410462 19115204 17242785 18815881 19288272 19084267 20005174 19200415 20065188 19011961 16873071 19221464 16273361 15668708 19066611 15565566 20390343 21152245 18855134 11161223 20859285 20544844 19103187 16818667 18425577 19289846 21138602 18997820 17049068 18629630 19244106 18984771
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9820435547
MESH:D002276 Carcinoid Tumor Doxorubicin 4.9116051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8416835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5819066611
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 8.967296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 8.963084413
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 8.9616023760 18059187 17876044 16234567
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 8.9617173139 1701930 20935162 20007298 6705139
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.9616924424
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 6.637296757
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.6316201981 1485588
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 10.9620419170
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 10.9611237771
MESH:D002294 Carcinoma, Squamous Cell decitabine 10.9619215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 10.966189445
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6617572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3916120746 18670907 18850075
MESH:D009202 Cardiomyopathies Doxorubicin 3.5616612575 18627295 16278810 17351982 17924179 16364871 17974986 16269455 17382496 16651473 16952015 17131338 15792986 16731534 17007740 15505089 16455267 16109756 16242529 17928571 15476868 17519947 15811867 17329180 17308081
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.9616243910 17334414
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 7.5214694615
MESH:D002386 Cataract Acetaminophen 7.5210977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 6.697505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.6912371664
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.324080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2116835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.629022650 19486331
MESH:D002779 Cholestasis Cyclosporine 13.6219486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.6215861022 11677210 17110522 16919318 17333356 16105132 17681005
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1215668235 8697196 12621046 16354765 15340226
MESH:D003110 Colonic Neoplasms decitabine 2.3417616700
MESH:D015179 Colorectal Neoplasms decitabine 2.7018981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.7018259882 18802399
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 9.3515095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 9.3514669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2610048152 20055451 15322242
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4319031437
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 7.3818759878 11906362 12868966 2524372 14531868 11298694 8970840 8156756
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 7.3816780908 16823706 11298694
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.553621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6817107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.5219279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 12.199653073 1440618 18648102 6679447 18289764 16192314 18692083 9328219 8291058 6482804 9022650 11289319 7440962
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 12.1921346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.1917562736 17906064 12153990 16177239 15619225 16081117 18713872 12958197 16485898 12705907 10774834 16109766 11739529 14725611 14550746 16781746 19420014 11421492 19370779 17522070 11529661 19085960 2444490 16227642 16393943 11834606 19923254 10663392 19164858 18071297 12540782 11461765 11743745 14986274 12594235 19416960 12392966 10915739 15968718 11287661 19739265
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 12.1917416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.1920420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1919426721
MESH:D004362 Drug Toxicity Doxorubicin 8.2418602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 8.2411462148
MESH:D004421 Dystonia Phenobarbital 4.061851702
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.4312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.0018230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 15.7415138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.7412538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.7419031437
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.2119294695
MESH:D016889 Endometrial Neoplasms Doxorubicin 7.6817359293
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.6819155303 16202921 17893378 20544844
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.0710568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.2518037988
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.183659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.973922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.9120417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.596401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.327750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.103659116
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.403581430
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.4016530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0511564622
MESH:D005234 Fatty Liver Cyclosporine 13.3819224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.3815345470
MESH:D005234 Fatty Liver Tamoxifen 13.3819224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2716709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5311858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.126705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.6114745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 11.7219069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 11.7219069698
MESH:D005355 Fibrosis Cyclosporine 8.7212639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.7220067830
MESH:D005756 Gastritis Acetaminophen 3.7716983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.308708960
MESH:D005909 Glioblastoma Doxorubicin 3.3817150277
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.107505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6910696789
MESH:D006258 Head and Neck Neoplasms decitabine 8.0819215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 8.0815692506
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.5420471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.5410048152 11294989
MESH:D006331 Heart Diseases Doxorubicin 3.5218674790 16495754 16244371 18006777 17888722 17875725 16144979 14766674 12587719 16244372 16707910 16879835 16330681
MESH:D006333 Heart Failure Doxorubicin 3.3717481944
MESH:D006394 Hemangiosarcoma Doxorubicin 3.9515692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.5015720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3911000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.586705139
MESH:D006529 Hepatomegaly Phenobarbital 8.6816109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.6816120746 15340226 12621046
MESH:D006689 Hodgkin Disease Doxorubicin 3.4517606976 15147373 18501091
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1416959395 8697196 16354765 18606429 15340226
MESH:D006930 Hyperalgesia Acetaminophen 2.7416870215
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.0115034207
MESH:D006973 Hypertension Cyclosporine 5.0110903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.0118670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8816569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5212013081
MESH:D007248 Infertility, Male decitabine 6.8417581917
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.8417937319
MESH:D007249 Inflammation Tamoxifen 4.9819457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.9812878042 12200463
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.128074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3916580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5415604871
MESH:D007674 Kidney Diseases Acetaminophen 10.2112587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 10.2118776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 10.2115699352 15369732 16775033
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.2116707910
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 12.646582329
MESH:D007680 Kidney Neoplasms Cyclosporine 12.6412371664
MESH:D007680 Kidney Neoplasms Tamoxifen 12.6418625569
MESH:D007938 Leukemia decitabine 3.1018980019 19235587
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.2516085563
MESH:D007951 Leukemia, Myeloid decitabine 4.0619117987 17236224 18454857
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.3918206229 19010910 19387464 18460780 18704418 17679729
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.5618055864
MESH:D008064 Lipidoses Tamoxifen 3.1917567588 15342952
MESH:D008103 Liver Cirrhosis Phenobarbital 2.9221047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.239327722 15034207
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 3.5316439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 3.5318564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.5312878042
MESH:D008107 Liver Diseases Acetaminophen 3.9719014921 12587719 19460945 11587558 12969438 16611625 19784758 16610002
MESH:D008107 Liver Diseases Phenobarbital 3.9719363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2916871587 17185352
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 10.8520195826 21137059
MESH:D008113 Liver Neoplasms Phenobarbital 10.8519812893 19482888 15975961 21047994 8742319 19073162
MESH:D008113 Liver Neoplasms Tamoxifen 10.8516684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.8516984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 14.40598648 6587162 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 14.4016842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 14.401399818 17172636 6150874 2563599 18308698
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.4012151625
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.896695378 18816296 20869020 18569708 17053015 20464547 18520028 20064080 20135361
MESH:D008175 Lung Neoplasms Doxorubicin 4.8917418594 6189445
MESH:D008175 Lung Neoplasms Tamoxifen 4.8918625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8911884234 19555203
MESH:D008223 Lymphoma decitabine 7.8519470736
MESH:D008223 Lymphoma Doxorubicin 7.8516098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.8317654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.6415621674
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8419428831
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 6.2515458769
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.2519196723 14580682 19196722 11731420 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 4.6419453300
MESH:D008545 Melanoma decitabine 5.2217785578 16505122
MESH:D008545 Melanoma Doxorubicin 5.2216827129
MESH:D008545 Melanoma Tamoxifen 5.2212393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2615990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6419513568
MESH:D008654 Mesothelioma Doxorubicin 3.0817638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8816801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.5515792986
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.2316381670
MESH:D052016 Mucositis Doxorubicin 4.8717415656
MESH:D009101 Multiple Myeloma decitabine 3.3818172295
MESH:D009190 Myelodysplastic Syndromes decitabine 3.4119157545 18608210 19010910 16882708
MESH:D009203 Myocardial Infarction Doxorubicin 2.9715857846 19429709
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0612213967
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.5617484760
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 9.633581430
MESH:D009362 Neoplasm Metastasis Doxorubicin 9.6318259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 9.6319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5319410462
MESH:D009369 Neoplasms Benzo(a)pyrene 5.1911141357
MESH:D009369 Neoplasms decitabine 5.1917925555 19470736 19116145
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.1019189210 19196722 19200415
MESH:D009401 Nephrosis Doxorubicin 4.8416899518 16636307
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 9.4618481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 9.4616889571 15640375
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2814600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.956679447
MESH:D009447 Neuroblastoma Doxorubicin 3.2915555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9118514411
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 9.304026338 6482804
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 9.3014694615
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.123988306
MESH:D010018 Osteomalacia Phenobarbital 4.4517016548
MESH:D012516 Osteosarcoma Doxorubicin 4.1615930896
MESH:D010051 Ovarian Neoplasms decitabine 2.6619259094 19331143
MESH:D010146 Pain Acetaminophen 2.4316870215
MESH:D010190 Pancreatic Neoplasms decitabine 5.4519294695
MESH:D010190 Pancreatic Neoplasms Phenobarbital 5.4516965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7511578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.557296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3512520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.576228378
MESH:D003557 Phyllodes Tumor Doxorubicin 5.2517983394
MESH:D010997 Pleural Neoplasms Doxorubicin 5.2517638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6218163543
MESH:D011230 Precancerous Conditions Cyclosporine 9.1312371664
MESH:D011230 Precancerous Conditions Phenobarbital 9.132563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2711222880 11896295 11399792 11118676
MESH:D055728 Primary Myelofibrosis decitabine 4.8017616702
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.8615572423
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0817292933
MESH:D011471 Prostatic Neoplasms Calcitriol 2.0816289102 12479363 15754350 16644109 18247401
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.0815897917 16729912 16868541 16888761 15749863 18437689
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0815067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.3915861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 4.5912752131
MESH:D011565 Psoriasis Cyclosporine 2.2416882103
MESH:D051437 Renal Insufficiency Doxorubicin 4.2917922066
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9018990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.413692021
MESH:D012208 Rhabdomyosarcoma decitabine 4.4619155313
MESH:D012509 Sarcoma Doxorubicin 4.0417710206 15625365 18313854 17203757 15675481 16767912
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.3114601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.8717846226
MESH:D012640 Seizures Phenobarbital 2.734039156 11442880 16876388 3137016
MESH:D003294 Seizures, Febrile Phenobarbital 4.906407741
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.5710029692 19755658
MESH:D012878 Skin Neoplasms Doxorubicin 9.5715692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.5716192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.6416767912 17203757 15625365
MESH:D013088 Spermatocele Ethinyl Estradiol 11.8916709447
MESH:D013088 Spermatocele Tamoxifen 11.8916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.1219457130
MESH:D013274 Stomach Neoplasms marker/mechanism 16367923
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.472093021 20155912
MESH:D013274 Stomach Neoplasms decitabine 2.4719037991
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2015669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0012697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 17.481399818 6582329 3712494 7505956 6587162
MESH:D013964 Thyroid Neoplasms decitabine 17.4817967635
MESH:D013964 Thyroid Neoplasms Doxorubicin 17.4816010429 17909728
MESH:D013964 Thyroid Neoplasms Phenobarbital 17.481399818
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 16.038074119
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 16.0317053015
MESH:D001749 Urinary Bladder Neoplasms decitabine 16.0317616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 16.0317653716
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 16.0317572228 16712894 8653321
MESH:D014581 Urticaria Acetaminophen 3.0310982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3614692618
MESH:D014604 Uveal Neoplasms decitabine 5.0117785578
MESH:D014605 Uveitis Cyclosporine 4.081336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6912125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5915869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.2917638931 17334414 16364871 17678736
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3515886252
MESH:D014985 Xerophthalmia Cyclosporine 4.5417120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134892011
    • No data
    Releated disease ID Related disease Name
    PA445425Prostatic Neoplasms
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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