AutismKB 2.0

Annotation Detail for KIAA0427


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Basic Information Top
Gene Symbol:KIAA0427 ( CTIF,Gm672 )
Gene Full Name: KIAA0427
Band: 18q21.1
Quick LinksEntrez ID:9811; OMIM: 613178; Uniprot ID:CTIF_HUMAN; ENSEMBL ID: ENSG00000134030; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CTIF mRNAdecreases expression 20064835
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CTIF mRNAaffects binding|decreases expression|increases activity 19710929
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.7218653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0720127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.906695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.3716434500
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.8419183758
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.7019483382
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9817474063 20146248
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1520419170
MESH:D002779 Cholestasis pirinixic acid 3.1919176532
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.6118249437
MESH:D004487 Edema pirinixic acid 3.0212083418
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0916530937
MESH:D005234 Fatty Liver pirinixic acid 3.3119236843 20131406
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8720471113
MESH:D006333 Heart Failure pirinixic acid 2.8120558911
MESH:D006529 Hepatomegaly pirinixic acid 3.7619772884 16221962 18467677 19176532
MESH:D006943 Hyperglycemia pirinixic acid 3.6920558911
MESH:D007333 Insulin Resistance pirinixic acid 2.9316306350
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.8520195826 21137059
MESH:D008113 Liver Neoplasms pirinixic acid 4.8515890375 16377806 20007298
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.576695378 20064080 18569708 20869020 18816296 18520028 20135361 17053015 20464547
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5716381670
MESH:D009135 Muscular Diseases pirinixic acid 4.2716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.3019151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.3316411023
MESH:D009369 Neoplasms Benzo(a)pyrene 5.5011141357
MESH:D009369 Neoplasms pirinixic acid 5.5017405874
MESH:D009765 Obesity pirinixic acid 1.9020558911
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9017292933
MESH:D015427 Reperfusion Injury pirinixic acid 2.5819058328
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5519755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.3217053015
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134974369
    • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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