AutismKB 2.0

Annotation Detail for CEP350


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Basic Information Top
Gene Symbol:CEP350 ( CAP350,FLJ38282,FLJ44058,GM133,KIAA0480 )
Gene Full Name: centrosomal protein 350kDa
Band: 1q25.2
Quick LinksEntrez ID:9857; OMIM: NA; Uniprot ID:CE350_HUMAN; ENSEMBL ID: ENSG00000135837; HGNC ID: 24238
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of CEP350 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of CEP350 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of CEP350 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CEP350 mRNAaffects expression 16483693
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CEP350 mRNAdecreases expression 19150397
20382639
20018196
D003010 Clorgyline Clorgyline results in increased expression of CEP350 mRNAincreases expression 19691856
C010327 salinomycin salinomycin results in decreased expression of CEP350 mRNAdecreases expression 19682730
D012643 Selenium [Selenium co-treated with Vitamin E] results in increased expression of CEP350 mRNAaffects cotreatment|increases expression 19244175
D012643 Selenium Selenium results in decreased expression of CEP350 mRNAdecreases expression 19244175
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in increased expression of CEP350 mRNAaffects cotreatment|increases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of CEP350 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.8418287403
MESH:D000799 Angioedema Acetaminophen 4.1610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms salinomycin 3.3319682730
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.1916050911
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.6616705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.6616705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.663084413
MESH:D002386 Cataract Acetaminophen 2.6910977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 7.106135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.1020889678
MESH:D003092 Colitis Selenium 4.0417936198
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 11.7718551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 11.7718551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 9.4221346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 9.4218551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.4217562736 16081117 16393943 10915739 12705907 19739265 10663392 11287661 16781746 16109766 18071297 11421492 11461765 17522070 12540782 15968718 12392966 17906064 19370779 11834606 10774834 2444490 16485898 16177239 11529661 16227642 18713872 19085960 14725611 19164858 19416960 19923254 11739529 12594235 11743745 19420014 12153990 12958197 14550746 15619225 14986274
MESH:D056486 Drug-Induced Liver Injury Selenium 9.4215131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.4219426721
MESH:C538011 Eales disease Vitamin E 5.029068938
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1120426865
MESH:D005756 Gastritis Acetaminophen 3.9916983495
MESH:D006330 Heart Defects, Congenital Vitamin E 3.0816080930
MESH:D006333 Heart Failure Selenium 3.1917162251
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7616490937 16863852
MESH:D019584 Hot Flashes Vitamin E 4.2914716179
MESH:D006930 Hyperalgesia Acetaminophen 2.8616870215
MESH:D007251 Influenza, Human Selenium 12.0416624496
MESH:D007251 Influenza, Human Vitamin E 12.0416624496
MESH:D007674 Kidney Diseases Acetaminophen 6.3315629191 12587719
MESH:D007674 Kidney Diseases Vitamin E 6.3312488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.0916518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 7.9416705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 7.9416705839
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9016169303
MESH:D008107 Liver Diseases Acetaminophen 1.6711587558 16611625 19460945 12969438 16610002 19784758 12587719 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.4316871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.217678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.662876784 6135515 2876786
MESH:D008171 Lung Diseases Vitamin E 3.3116863852
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D008325 Mammary Neoplasms, Experimental salinomycin 6.8819682730
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.8815318939
MESH:D008546 Melanoma, Experimental Acetaminophen 3.8319513568
MESH:D008654 Mesothelioma Selenium 2.8615107826
MESH:D009336 Necrosis 2,4-dinitrotoluene 11.3218551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 11.327678174 18551238
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.0418514411
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.5412819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 9.5416049721
MESH:D010146 Pain Acetaminophen 2.5616870215
MESH:D010954 Plasmacytoma Selenium 5.2115087411
MESH:D011471 Prostatic Neoplasms Clorgyline 3.6319691856
MESH:D011471 Prostatic Neoplasms Vitamin E 3.6315084515
MESH:D012640 Seizures 2,4-dinitrotoluene 6.3218551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.3218551238
MESH:D012871 Skin Diseases Vitamin E 2.4818709164
MESH:D020521 Stroke Vitamin E 3.6816517955
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.2416049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.2416049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 12.9610091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 12.9610091137
MESH:D014581 Urticaria Acetaminophen 3.2010982225
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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