AutismKB 2.0

Annotation Detail for URB1


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Basic Information Top
Gene Symbol:URB1 ( C21orf108,KIAA0539,NPA1 )
Gene Full Name: URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
Band: 21q22.11
Quick LinksEntrez ID:9875; OMIM: 608865; Uniprot ID:NPA1P_HUMAN; ENSEMBL ID: ENSG00000142207; HGNC ID: 17344
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of URB1 mRNAaffects expression 17562736
D015525 Fatty Acids, Omega-3 Fatty Acids, Omega-3 results in increased expression of URB1 mRNAincreases expression 16823509
D043371 Fatty Acids, Omega-6 Fatty Acids, Omega-6 results in decreased expression of URB1 mRNAdecreases expression 16823509
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.7110982225
MESH:D001289 Attention Deficit Disorder with Hyperactivity Fatty Acids, Omega-3 10.2118448859
MESH:D001289 Attention Deficit Disorder with Hyperactivity Fatty Acids, Omega-6 10.2118448859
MESH:D001321 Autistic Disorder Acetaminophen 2.4018445737
MESH:D001321 Autistic Disorder Fatty Acids, Omega-3 2.4016920077
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8110977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.682444490 11743745 16393943 14550746 19085960 11739529 15619225 12153990 11421492 19416960 17522070 18713872 19164858 11461765 19420014 10663392 16781746 12540782 14725611 11529661 12958197 19739265 16109766 12392966 16081117 10774834 10915739 15968718 12705907 17562736 16485898 14986274 16177239 18071297 19370779 11287661 17906064 19923254 12594235 16227642 11834606
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.9619426721
MESH:D005756 Gastritis Acetaminophen 4.5416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.0616870215
MESH:D007249 Inflammation Fatty Acids, Omega-3 4.1617296493
MESH:D007674 Kidney Diseases Acetaminophen 2.4215629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7116610002 16611625 12587719 19460945 19014921 12969438 19784758 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6817185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.2219513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.2618514411
MESH:D010146 Pain Acetaminophen 2.7716870215
MESH:D014581 Urticaria Acetaminophen 3.5010982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018