AutismKB 2.0

Annotation Detail for ZC3H11A


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Basic Information Top
Gene Symbol:ZC3H11A ( DKFZp686D03108,DKFZp686F14109,DKFZp781G2455,KIAA0663,ZC3HDC11A )
Gene Full Name: zinc finger CCCH-type containing 11A
Band: 1q32.1
Quick LinksEntrez ID:9877; OMIM: 613513; Uniprot ID:ZC11A_HUMAN; ENSEMBL ID: ENSG00000058673; HGNC ID: 29093
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of ZC3H11A mRNAincreases expression 16788091
D000082 Acetaminophen Acetaminophen affects the expression of ZC3H11A mRNAaffects expression 17562736
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZC3H11A mRNAdecreases expression 20018196
D014302 Trinitrobenzenesulfonic Acid Trinitrobenzenesulfonic Acid results in decreased expression of ZC3H11A mRNAdecreases expression 17982090
C025643 vinclozolin vinclozolin affects the expression of ZC3H11A mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001008 Anxiety Disorders vinclozolin 3.9319015723
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.403084413
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.9620889678
MESH:D003092 Colitis Trinitrobenzenesulfonic Acid 5.0316474422 17991707 16867261 11698051 16782535 17936198 18023891 18200517 16804969
MESH:D003093 Colitis, Ulcerative Trinitrobenzenesulfonic Acid 3.5317276891
MESH:D003456 Cryptorchidism vinclozolin 4.7814966744
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6611834606 12705907 19416960 12540782 16081117 18713872 17562736 11739529 14986274 11529661 16109766 12153990 16485898 18071297 15619225 11743745 14725611 17906064 16781746 14550746 19370779 19164858 11421492 11287661 12392966 10774834 19420014 11461765 10663392 19085960 15968718 19739265 16227642 16177239 10915739 12958197 12594235 19923254 16393943 17522070 2444490
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1420426865
MESH:D005355 Fibrosis Trinitrobenzenesulfonic Acid 4.8417994277
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.4716973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.9116417039
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D007248 Infertility, Male vinclozolin 3.2616467254
MESH:D015212 Inflammatory Bowel Diseases Trinitrobenzenesulfonic Acid 3.6918200517
MESH:D007410 Intestinal Diseases Trinitrobenzenesulfonic Acid 5.0917994277
MESH:D007674 Kidney Diseases Acetaminophen 2.3815629191 12587719
MESH:D007984 Leydig Cell Tumor vinclozolin 5.2716417039
MESH:D008107 Liver Diseases Acetaminophen 1.6912587719 16611625 19784758 19460945 11587558 12969438 16610002 19014921
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5817185352 16871587
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D010195 Pancreatitis Trinitrobenzenesulfonic Acid 4.6017698068
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.4418042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.4718220299
MESH:D011472 Prostatitis vinclozolin 5.4718629315
MESH:D014581 Urticaria Acetaminophen 3.3810982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018