Annotation Detail for TELO2
Basic Information
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| Gene Symbol: | TELO2 ( CLK2,DKFZp434A073,FLJ10924,KIAA0683,TEL2 ) |
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| Gene Full Name: | TEL2, telomere maintenance 2, homolog (S. cerevisiae) |
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| Band: | 16p13.3 |
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| Quick Links | Entrez ID:9894; OMIM: 611140; Uniprot ID:TELO2_HUMAN; ENSEMBL ID: ENSG00000100726; HGNC ID: 29099 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D004958 |
Estradiol |
Estradiol results in decreased expression of TELO2 mRNA | decreases expression | 16705744
|
| D019833 |
Genistein |
Genistein results in decreased expression of TELO2 mRNA | decreases expression | 16705744
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000230 |
Adenocarcinoma |
|
Estradiol |
4.77 | 11473722 |
| MESH:D000230 |
Adenocarcinoma |
|
Genistein |
4.77 | 11473722 |
| MESH:D001943 |
Breast Neoplasms |
|
Estradiol |
2.20 | 12948864 18497071 16675129 17289903 14630087 17018787 19861407 17261762 |
| MESH:D001943 |
Breast Neoplasms |
|
Genistein |
2.20 | 16873071 16541309 17200150 |
| MESH:D002181 |
Candidiasis, Vulvovaginal |
|
Estradiol |
5.35 | 16111702 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Estradiol |
3.27 | 16924424 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Genistein |
3.27 | 16924424 |
| MESH:D002318 |
Cardiovascular Diseases |
|
Genistein |
3.63 | 16332659 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Estradiol |
3.09 | 18566989 |
| MESH:D003110 |
Colonic Neoplasms |
|
Genistein |
2.34 | 17182828 |
| MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
Genistein |
2.57 | 16647724 |
| MESH:D003928 |
Diabetic Nephropathies |
|
Estradiol |
3.88 | 19279558 |
| MESH:D004714 |
Endometrial Hyperplasia |
|
Genistein |
5.48 | 16402032 |
| MESH:D016889 |
Endometrial Neoplasms |
|
Estradiol |
8.51 | 19148513 11473722 18566989 |
| MESH:D016889 |
Endometrial Neoplasms |
|
Genistein |
8.51 | 11473722 |
| MESH:D005909 |
Glioblastoma |
|
Genistein |
3.55 | 16598420 |
| MESH:D006558 |
Herpes Genitalis |
|
Estradiol |
6.10 | 15709030 |
| MESH:D019584 |
Hot Flashes |
|
Estradiol |
4.82 | 17088409 |
| MESH:D007333 |
Insulin Resistance |
|
Estradiol |
3.26 | 16393666 16627594 |
| MESH:D007674 |
Kidney Diseases |
|
Estradiol |
2.83 | 15618244 |
| MESH:D007680 |
Kidney Neoplasms |
|
Estradiol |
3.41 | 15610895 |
| MESH:D007938 |
Leukemia |
|
Genistein |
3.22 | 18980019 17468513 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Estradiol |
2.67 | 14659978 14716833 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Genistein |
2.67 | 17823541 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Estradiol |
7.07 | 11807958 16891317 11408345 17203775 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Genistein |
7.07 | 12929590 14578162 |
| MESH:D020149 |
Manganese Poisoning |
|
Estradiol |
5.55 | 19453300 |
| MESH:D009203 |
Myocardial Infarction |
|
Genistein |
3.02 | 17141266 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
Estradiol |
9.81 | 16810080 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
Genistein |
9.81 | 17141266 |
| MESH:D009389 |
Neovascularization, Pathologic |
|
Estradiol |
4.62 | 17289903 |
| MESH:D009421 |
Nervous System Malformations |
|
Estradiol |
12.11 | 11399458 16427766 |
| MESH:D009421 |
Nervous System Malformations |
|
Genistein |
12.11 | 16427766 |
| MESH:D010024 |
Osteoporosis |
|
Genistein |
3.52 | 19401787 |
| MESH:D015663 |
Osteoporosis, Postmenopausal |
|
Genistein |
4.69 | 16169203 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Estradiol |
5.29 | 19401270 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Genistein |
5.29 | 19005980 |
| MESH:D019048 |
Prostatic Intraepithelial Neoplasia |
|
Estradiol |
4.44 | 20887781 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Estradiol |
3.19 | 16740699 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Genistein |
3.19 | 15256057 15378649 16925846 |
| MESH:D013978 |
Tibial Fractures |
|
Estradiol |
5.76 | 19048282 |
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