Gene Symbol:	FAM20B ( gxk1 )
Gene Full Name:	family with sequence similarity 20, member B
Band:	1q25.2
Quick Links	Entrez ID:9917; OMIM: 611063; Uniprot ID:XYLK_HUMAN; ENSEMBL ID: ENSG00000116199; HGNC ID: 23017
Relate to Another Database:	SFARIGene; denovo-db

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D015123	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of FAM20B mRNA	decreases expression	20018196
D004052	Diethylnitrosamine	Diethylnitrosamine results in increased expression of FAM20B mRNA	increases expression	17942915
D004052	Diethylnitrosamine	MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of FAM20B mRNA]	decreases reaction\|increases expression	17942915

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D000236	Adenoma	Diethylnitrosamine	3.10	10737359 6695378
MESH:D018248	Adenoma, Liver Cell	Diethylnitrosamine	4.79	17162532 19061943 18056438 17620307 16434500 19052882
MESH:D001943	Breast Neoplasms	Diethylnitrosamine	2.18	17474063
MESH:D006528	Carcinoma, Hepatocellular	Diethylnitrosamine	1.88	20214788 20512989 16935385 18056438 19701751 18691550 19208518 16681979 17055752 3581430 19539802 16830150 17761372 18494052 18393292 19919837 16502159 19335982 16328049 19418558 18210153 18788625 19052882 20101231 3084413 16698587 10672840 20432363 20514400 17428255 20727157 19383236 16569478 20007298 21159647 20084675 19171122 19107877 11831363 19519916 17138121 10737359 17978847 20524982 16288022 18665156 19822196 18978308 18506893 17162532 17173139 16878318 16779866 16807293 18785209 20935162 16540662 19394651 18971187
MESH:D002471	Cell Transformation, Neoplastic	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	7.77	20889678
MESH:D002471	Cell Transformation, Neoplastic	Diethylnitrosamine	7.77	17174075 21159647 7505956 2727394
MESH:D018281	Cholangiocarcinoma	Diethylnitrosamine	4.15	19052882
MESH:D003924	Diabetes Mellitus, Type 2	Diethylnitrosamine	2.27	20387270
MESH:D056486	Drug-Induced Liver Injury	Diethylnitrosamine	2.15	19107877
MESH:D004931	Esophageal Achalasia	Diethylnitrosamine	6.19	16302075
MESH:D004938	Esophageal Neoplasms	7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide	2.16	20426865
MESH:D005234	Fatty Liver	Diethylnitrosamine	3.73	20387270 21071580
MESH:D007249	Inflammation	Diethylnitrosamine	2.59	18785209
MESH:D008103	Liver Cirrhosis	Diethylnitrosamine	3.05	19638242 18522880 18407596 18665156 20032147
MESH:D008107	Liver Diseases	Diethylnitrosamine	2.18	17034775
MESH:D008113	Liver Neoplasms	Diethylnitrosamine	2.37	12112319 19642983 19638242 20118626 19073162 19833225 20137499 20492335 21278145 19090486 19499222 19427195 12771043 18978307 19294768 2422723 19254457 19256749 19812893 20501860 15175105 19996281 18648771 16942905 20101389 21167192 20452335 19551842 18754104 15885732 19690152 19850985 19426721 20405173 18977376 19255062 18644402 2862719 20434301 21071580 10737359 21047994 9163691 20583210
MESH:D008114	Liver Neoplasms, Experimental	Diethylnitrosamine	2.90	18544905 17942915 18079962 2563599 18775883 18093689 18282651 16842330 19009564 17174075 19519916 18253720 19004024 21159647 19126423 16267830 9362446 17854601 19539802 3124819 18164116 18308698
MESH:D008175	Lung Neoplasms	Diethylnitrosamine	1.77	21163286 20970405 20512841 6695378
MESH:D009362	Neoplasm Metastasis	Diethylnitrosamine	2.72	9029167 3581430
MESH:D019636	Neurodegenerative Diseases	Diethylnitrosamine	3.78	20387270
MESH:D009461	Neurologic Manifestations	Diethylnitrosamine	6.19	20387270
MESH:D010190	Pancreatic Neoplasms	Diethylnitrosamine	2.55	16540662
MESH:D011230	Precancerous Conditions	Diethylnitrosamine	4.02	2563599
MESH:D013274	Stomach Neoplasms	Diethylnitrosamine	1.76	18456281
MESH:D013964	Thyroid Neoplasms	Diethylnitrosamine	3.36	7505956

AutismKB 2.0

Annotation Detail for FAM20B

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics