AutismKB 2.0

Annotation Detail for NCAPD2


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Basic Information Top
Gene Symbol:NCAPD2 ( CAP-D2,CNAP1,KIAA0159,hCAP-D2 )
Gene Full Name: non-SMC condensin I complex, subunit D2
Band: 12p13.31
Quick LinksEntrez ID:9918; OMIM: NA; Uniprot ID:CND1_HUMAN; ENSEMBL ID: ENSG00000010292; HGNC ID: 24305
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200010Aurora B signaling
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of NCAPD2 mRNAaffects expression 17562736
C015001 arsenite arsenite results in decreased expression of NCAPD2 mRNAdecreases expression 18929588
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NCAPD2 mRNAdecreases expression 20018196
20382639
C006780 bisphenol A bisphenol A results in increased expression of NCAPD2 mRNAincreases expression 16474171
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of NCAPD2 mRNAdecreases expression 15336504
D003345 Corticosterone Corticosterone results in decreased expression of NCAPD2 mRNAdecreases expression 15755911
D016572 Cyclosporine Cyclosporine results in decreased expression of NCAPD2 mRNAdecreases expression 20106945
D004958 Estradiol Estradiol results in increased expression of NCAPD2 mRNAincreases expression 16474171
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of NCAPD2 mRNAaffects expression 17555576
D019833 Genistein Genistein results in increased expression of NCAPD2 mRNAincreases expression 16474171
C006253 pirinixic acid pirinixic acid results in decreased expression of NCAPD2 mRNAdecreases expression 17426115
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls analog results in increased expression of NCAPD2 mRNAincreases expression 16474171
C410733 scriptaid scriptaid affects the expression of NCAPD2 mRNAaffects expression 18813790
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0817505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.2018653653
MESH:D000230 Adenocarcinoma Estradiol 7.1811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 7.1814692618
MESH:D000230 Adenocarcinoma Genistein 7.1811473722
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.6016434500
MESH:D000799 Angioedema Acetaminophen 3.9810982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.7115885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.2319483382
MESH:D001862 Bone Resorption bisphenol A 3.9411985600
MESH:D001943 Breast Neoplasms bisphenol A 1.9617123778
MESH:D001943 Breast Neoplasms Estradiol 1.9617261762 12948864 17018787 18497071 16675129 17289903 19861407 14630087
MESH:D001943 Breast Neoplasms Genistein 1.9616873071 17200150 16541309
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.5816111702
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.633084413
MESH:D006528 Carcinoma, Hepatocellular Estradiol 4.6316924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 4.6316924424
MESH:D002278 Carcinoma in Situ bisphenol A 5.1117123778
MESH:D002318 Cardiovascular Diseases Genistein 3.3616332659
MESH:D002386 Cataract Acetaminophen 2.6310977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.4620889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 11.4612371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 11.4618566989
MESH:D002779 Cholestasis Cyclosporine 13.7019486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.7016919318 15861022 17681005 17333356 11677210 17110522 16105132
MESH:D002779 Cholestasis pirinixic acid 13.7019176532
MESH:D003110 Colonic Neoplasms arsenite 4.0315037631
MESH:D003110 Colonic Neoplasms Genistein 4.0317182828
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 2.7315531428
MESH:D003704 Dementia Polychlorinated Biphenyls 4.7816140633
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4618249437
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 2.5016647724
MESH:D003928 Diabetic Nephropathies Estradiol 3.4819279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6115619225 12540782 17562736 19416960 16109766 14725611 10663392 10915739 12392966 11739529 19923254 12705907 19370779 17522070 2444490 17906064 16081117 12958197 18713872 11529661 16485898 16227642 19420014 18071297 19164858 19739265 10774834 11421492 12153990 15968718 16393943 11461765 12594235 14986274 11834606 16781746 16177239 14550746 11287661 11743745 19085960
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.2319426721
MESH:D004487 Edema pirinixic acid 2.5612083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.2812538720
MESH:D004714 Endometrial Hyperplasia Genistein 4.7116402032
MESH:D016889 Endometrial Neoplasms Estradiol 7.6811473722 19148513 18566989
MESH:D016889 Endometrial Neoplasms Genistein 7.6811473722
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.0920426865
MESH:D005234 Fatty Liver arsenite 19.4718296743
MESH:D005234 Fatty Liver Cyclosporine 19.4719224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 19.4715345470
MESH:D005234 Fatty Liver pirinixic acid 19.4720131406 19236843
MESH:D005355 Fibrosis arsenite 9.2418296743
MESH:D005355 Fibrosis Cyclosporine 9.2412168785 12639820
MESH:D005756 Gastritis Acetaminophen 3.8116983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.348708960
MESH:D005909 Glioblastoma Genistein 3.3116598420
MESH:D006333 Heart Failure pirinixic acid 2.5820558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.5415720958
MESH:D006529 Hepatomegaly pirinixic acid 3.1016221962 19176532 19772884 18467677
MESH:D006558 Herpes Genitalis Estradiol 5.1715709030
MESH:D019584 Hot Flashes Estradiol 3.8917088409
MESH:D006930 Hyperalgesia Acetaminophen 2.7616870215
MESH:D006943 Hyperglycemia pirinixic acid 3.2620558911
MESH:D006973 Hypertension Cyclosporine 2.1210903974
MESH:D007021 Hypospadias Ethinyl Estradiol 3.9116569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5512013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5417937319
MESH:D007333 Insulin Resistance bisphenol A 12.6216393666
MESH:D007333 Insulin Resistance Estradiol 12.6216627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 12.6216306350
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5815604871
MESH:D007674 Kidney Diseases Acetaminophen 10.2415629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 10.248314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 10.2415618244
MESH:D007680 Kidney Neoplasms Cyclosporine 7.5012371664
MESH:D007680 Kidney Neoplasms Estradiol 7.5015610895
MESH:D007938 Leukemia Genistein 3.0618980019 17468513
MESH:D008103 Liver Cirrhosis arsenite 3.4618296743
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.5314716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 3.5317823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.5315474484
MESH:D008107 Liver Diseases Acetaminophen 1.6511587558 19014921 16611625 19784758 12587719 12969438 16610002 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.3116871587 17185352
MESH:D008113 Liver Neoplasms pirinixic acid 1.8415890375 16377806 20007298
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 3.651423854
MESH:D008175 Lung Neoplasms arsenite 2.3516809336
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 10.4212807724
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 10.4216891317 11807958 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 10.4214578162 12929590
MESH:D020149 Manganese Poisoning Estradiol 4.6219453300
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6719513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.9216801185
MESH:D009135 Muscular Diseases pirinixic acid 3.6116239165
MESH:D009203 Myocardial Infarction Genistein 5.7817141266
MESH:D009203 Myocardial Infarction pirinixic acid 5.7819151258
MESH:D015428 Myocardial Reperfusion Injury Estradiol 14.5416810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 14.5417141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 14.5416411023
MESH:D009369 Neoplasms pirinixic acid 1.9817405874
MESH:D009389 Neovascularization, Pathologic arsenite 10.5515738583
MESH:D009389 Neovascularization, Pathologic Estradiol 10.5517289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3618481113 19348381
MESH:D009421 Nervous System Malformations bisphenol A 17.0416427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 17.0411399458 16427766
MESH:D009421 Nervous System Malformations Genistein 17.0416427766
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9418514411
MESH:D009765 Obesity pirinixic acid 1.8320558911
MESH:D010024 Osteoporosis Genistein 3.3019401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 4.1716169203
MESH:D010049 Ovarian Diseases bisphenol A 5.1111985600
MESH:D010051 Ovarian Neoplasms Estradiol 4.9819401270
MESH:D010051 Ovarian Neoplasms Genistein 4.9819005980
MESH:D010146 Pain Acetaminophen 2.4616870215
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7711578682
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 3.4216702228
MESH:D011230 Precancerous Conditions Cyclosporine 3.2912371664
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 4.0710548101
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 10.8320887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 10.8320887781
MESH:D011471 Prostatic Neoplasms bisphenol A 2.1216740699
MESH:D011471 Prostatic Neoplasms Estradiol 2.1216740699
MESH:D011471 Prostatic Neoplasms Genistein 2.1215256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 2.1215721890
MESH:D011537 Pruritus Ethinyl Estradiol 3.4316919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.2516882103
MESH:D011629 Puberty, Precocious bisphenol A 4.9010548101
MESH:D015427 Reperfusion Injury pirinixic acid 2.4219058328
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 2.728532709
MESH:D013088 Spermatocele Ethinyl Estradiol 4.0816709447
MESH:D019966 Substance-Related Disorders bisphenol A 4.1016045194 16684133
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.7111994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2215669648
MESH:D013978 Tibial Fractures Estradiol 4.8219048282
MESH:D014581 Urticaria Acetaminophen 3.0610982225
MESH:D014591 Uterine Diseases bisphenol A 5.1414652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3914692618
MESH:D014605 Uveitis Cyclosporine 4.121336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.6215869587 14671159
MESH:D014985 Xerophthalmia Cyclosporine 4.5817120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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