Annotation Detail for PAN2
Basic Information
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| Gene Symbol: | PAN2 ( FLJ39360,KIAA0710,USP52 ) |
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| Gene Full Name: | PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) |
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| Band: | 12q13.3 |
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| Quick Links | Entrez ID:9924; OMIM: NA; Uniprot ID:PAN2_HUMAN; ENSEMBL ID: ENSG00000135473; HGNC ID: 20074 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| Metabolism of RNA |
| Pathway ID | Pathway Name |
|---|
| 500855 | Deadenylation of mRNA |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D016604 |
Aflatoxin B1 |
Aflatoxin B1 affects the expression of PAN2 protein | affects expression | 20106945
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of PAN2 mRNA | affects binding|increases activity|increases expression | 19710929
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.72 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.37 | 16434500 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.70 | 19483382 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Aflatoxin B1 |
1.99 | 21507988 12907637 12619106 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.19 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.61 | 18249437 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
3.02 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.31 | 19236843 20131406 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.81 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.76 | 16221962 19772884 18467677 19176532 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.69 | 20558911 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.93 | 16306350 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
Aflatoxin B1 |
4.97 | 9163691 15890375 18177683 2125692 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
4.97 | 20007298 16377806 15890375 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Aflatoxin B1 |
3.01 | 8603461 |
| MESH:D008175 |
Lung Neoplasms |
|
Aflatoxin B1 |
1.88 | 14755239 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.27 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.30 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.33 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.14 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.90 | 20558911 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.58 | 19058328 |
Related Diseases/Disorders