AutismKB 2.0

Annotation Detail for WDR1


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Basic Information Top
Gene Symbol:WDR1 ( AIP1,NORI-1 )
Gene Full Name: WD repeat domain 1
Band: 4p16.1
Quick LinksEntrez ID:9948; OMIM: 604734; Uniprot ID:WDR1_HUMAN; ENSEMBL ID: ENSG00000071127; HGNC ID: 12754
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1894Abortion
Desease Name
serum uric acid
METABOLIC
serum urate
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of WDR1 mRNAincreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of WDR1 mRNAaffects expression 17562736
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of WDR1 mRNAdecreases expression 20018196
19150397
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of WDR1 mRNAincreases expression 15336504
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of WDR1 mRNAincreases expression 19638242
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of WDR1 mRNAincreases expression 17555576
14976129
17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of WDR1 mRNAaffects cotreatment|increases expression 17942748
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of WDR1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of WDR1 mRNAincreases expression 19482888
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of WDR1 mRNAaffects binding|decreases expression|increases activity 19710929
C037219 quinoline quinoline analog results in increased expression of WDR1 proteinincreases expression 18645022
D020849 Raloxifene Raloxifene affects the expression of WDR1 mRNAaffects expression 14699072
D012643 Selenium Selenium results in increased expression of WDR1 mRNAincreases expression 19244175
D013629 Tamoxifen Tamoxifen affects the expression of WDR1 mRNAaffects expression 14699072
D013629 Tamoxifen Tamoxifen affects the expression of WDR1 mRNAaffects expression 17555576
C020806 tetrabromobisphenol A tetrabromobisphenol A results in decreased expression of WDR1 mRNAdecreases expression 18976794
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of WDR1 mRNAaffects cotreatment|increases expression 17942748
D014810 Vitamin E Vitamin E results in increased expression of WDR1 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6114745880
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 8.466195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.4615322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0017505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.1518653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8214692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.723712494
MESH:D000236 Adenoma Diethylnitrosamine 6.726695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 25.3317620307 19061943 18056438 19052882 16434500 17162532
MESH:D018248 Adenoma, Liver Cell Phenobarbital 25.3317620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 25.3316434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 25.3316835633
MESH:D000419 Albuminuria Raloxifene 4.6317451421 17308373
MESH:D000544 Alzheimer Disease Raloxifene 2.5515800139
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9711748828
MESH:D000799 Angioedema Acetaminophen 3.9110982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6815885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.081440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.8619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.8612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7815746008
MESH:D001930 Brain Injuries Raloxifene 4.5216580743
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9517474063
MESH:D001943 Breast Neoplasms Raloxifene 1.9517049068 16837676 17952589 17595753 17242785 17893378 17261762 16912660 15775269 15758505 15572757 17440819
MESH:D001943 Breast Neoplasms Tamoxifen 1.9518984771 21152245 20065188 19487384 18629630 19189210 16273361 19011961 19244106 11161223 19103187 17893378 18821012 19115204 18855134 19059307 18997820 19084267 19142967 20135344 19289846 19155303 16818667 19288272 19066611 18351453 18425577 15565566 20005174 16873071 16202921 17049068 18815881 20390343 19410462 15668708 19200415 17242785 17261762 17440819 20544844 21138602 19221464 20859285 19189212
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9520435547
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.9716050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8216835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5519066611
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 11.473581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.473084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.4717173139 19335982 19539802 3581430 20935162 18978308 16807293 20514400 18393292 19208518 18506893 18056438 19052882 18691550 18785209 16681979 11831363 19919837 19519916 17055752 16288022 18788625 3084413 17162532 17761372 20432363 18210153 18494052 19394651 20727157 17138121 20101231 17428255 20524982 20084675 16935385 17978847 20007298 19171122 19822196 19701751 19418558 16540662 20512989 16779866 19383236 16698587 18665156 20214788 16569478 10737359 10672840 19107877 21159647 18971187 16502159 16878318 16328049 16830150
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 11.476705139 20007298 20935162 1701930 17173139
MESH:D006528 Carcinoma, Hepatocellular quinoline 11.47598648
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 11.4716924424
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.697296757
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 9.5917572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 9.5917572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3818850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases Raloxifene 3.4615775269
MESH:D002386 Cataract Acetaminophen 2.6010977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 11.297505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.2920889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 11.2917174075 7505956 21159647 2727394
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.294080065
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.4119052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.4116835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 13.509022650 19486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.5017110522 16105132 15861022 16919318 17333356 11677210 17681005
MESH:D002779 Cholestasis pirinixic acid 13.5019176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1116354765 12621046 8697196 15668235 15340226
MESH:D003072 Cognition Disorders Raloxifene 4.6615800139
MESH:D003092 Colitis Selenium 3.8217936198
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0817141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4920055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.4919769572
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4019031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.1917474826
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.8411906362 18759878 8156756 11298694 2524372 12868966 14531868 8970840
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4418249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.523621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.2420387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2417107852
MESH:D003928 Diabetic Nephropathies Raloxifene 9.1215920148 17451421 17308373
MESH:D003928 Diabetic Nephropathies Tamoxifen 9.1219279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 12.108291058 6679447 9653073 1440618 18648102 9022650 18692083 16192314 18289764 9328219 7440962 11289319 6482804
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.1015619225 14550746 19164858 12540782 12594235 10663392 17562736 16177239 19923254 16081117 12392966 12705907 19370779 10915739 16393943 17906064 16485898 11529661 19420014 16781746 10774834 18713872 15968718 17522070 11739529 11287661 11834606 19739265 11743745 19416960 12153990 11461765 18071297 14986274 16109766 11421492 16227642 14725611 2444490 12958197 19085960
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 12.1019107877
MESH:D056486 Drug-Induced Liver Injury Selenium 12.1015131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.1020420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1619426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7811462148
MESH:D004421 Dystonia Phenobarbital 4.041851702
MESH:C538011 Eales disease Vitamin E 4.779068938
MESH:D004487 Edema pirinixic acid 11.6012083418
MESH:D004487 Edema Raloxifene 11.6015860553
MESH:D004487 Edema Tetrachlorodibenzodioxin 11.6011000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9618230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 15.5812538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 15.5815845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 15.5819031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.0617893378 16202921 20544844 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.0510568697 9294722
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.153659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.933922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.9020417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.576401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.297750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.073659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.1816302075
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.413581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.4120426865
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0311564622
MESH:D005234 Fatty Liver Diethylnitrosamine 24.9920387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 24.9915345470
MESH:D005234 Fatty Liver pirinixic acid 24.9919236843 20131406
MESH:D005234 Fatty Liver Raloxifene 24.9917473493
MESH:D005234 Fatty Liver Tamoxifen 24.9919224547 14986274
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2516709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.086705139
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.5814745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2319069698
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.9920067830
MESH:D005756 Gastritis Acetaminophen 3.7416983495
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.077505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.6211294989 10048152
MESH:D006330 Heart Defects, Congenital Vitamin E 6.6216080930
MESH:D006331 Heart Diseases Raloxifene 3.5511110106
MESH:D006333 Heart Failure pirinixic acid 7.0120558911
MESH:D006333 Heart Failure Selenium 7.0117162251
MESH:D006390 Hemangioendothelioma quinoline 5.97598648
MESH:D006394 Hemangiosarcoma quinoline 5.02598648
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.556705139
MESH:D006529 Hepatomegaly Phenobarbital 14.6416109766
MESH:D006529 Hepatomegaly pirinixic acid 14.6418467677 19176532 16221962 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 14.6415340226 12621046 16120746
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7116863852 16490937
MESH:D019584 Hot Flashes Vitamin E 4.0314716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1116354765 18606429 16959395 15340226 8697196
MESH:D006930 Hyperalgesia Acetaminophen 2.7216870215
MESH:D006943 Hyperglycemia pirinixic acid 3.2120558911
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.9815034207
MESH:D006973 Hypertension Raloxifene 5.2615787275 17577099
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.2618670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5017937319
MESH:D007249 Inflammation Diethylnitrosamine 8.3518785209
MESH:D007249 Inflammation Tamoxifen 8.3519457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.3512878042 12200463
MESH:D007251 Influenza, Human Selenium 11.1716624496
MESH:D007251 Influenza, Human Vitamin E 11.1716624496
MESH:D007333 Insulin Resistance pirinixic acid 2.6516306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.088074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3616580747
MESH:D007674 Kidney Diseases Acetaminophen 6.0215629191 12587719
MESH:D007674 Kidney Diseases Vitamin E 6.0212488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.9116518626
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 7.466582329
MESH:D007680 Kidney Neoplasms Tamoxifen 7.4618625569
MESH:D007889 Leiomyoma Raloxifene 4.5316973256
MESH:D008064 Lipidoses Tamoxifen 3.1717567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.6918665156 19638242 20032147 18522880 18407596
MESH:D008103 Liver Cirrhosis Phenobarbital 6.6921047994
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2115034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9515474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.9518564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9512878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.9516169303
MESH:D008107 Liver Diseases Acetaminophen 6.5319460945 16611625 11587558 16610002 12587719 19014921 12969438 19784758
MESH:D008107 Liver Diseases Diethylnitrosamine 6.5317034775
MESH:D008107 Liver Diseases Phenobarbital 6.5319363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.2616871587 17185352
MESH:D008113 Liver Neoplasms Diethylnitrosamine 14.3410737359 19833225 12112319 2422723 19256749 19294768 21278145 15885732 20405173 20583210 20137499 19499222 20492335 19427195 9163691 18648771 19426721 18978307 18644402 20118626 12771043 2862719 19690152 19254457 20452335 19255062 18754104 19642983 19812893 16942905 15175105 18977376 19638242 19551842 20501860 19073162 19996281 20434301 21071580 19850985 21167192 19090486 21047994 20101389
MESH:D008113 Liver Neoplasms Phenobarbital 14.3415975961 8742319 19482888 19073162 19812893 21047994
MESH:D008113 Liver Neoplasms pirinixic acid 14.3420007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tamoxifen 14.3416684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.3416984957
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 14.256587162 3712494 1399818 598648
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 14.2518544905 19539802 18079962 19004024 18775883 18093689 17942915 18253720 18282651 16842330 18164116 19519916 19009564 18308698 16267830 21159647 2563599 17854601 17174075 3124819 19126423 9362446
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 14.2517172636 1399818 18308698 2563599 6150874
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.2512151625
MESH:D008171 Lung Diseases Vitamin E 3.1916863852
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.8620970405 21163286 6695378 20512841
MESH:D008175 Lung Neoplasms Tamoxifen 4.8618625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8611884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 4.8611062179
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8119428831
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.1015318939
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.1019196723 11731420 16827153 14580682 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.6119453300
MESH:D008545 Melanoma Tamoxifen 1.8819393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2315990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6119513568
MESH:D008654 Mesothelioma Selenium 2.8015107826
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.6215863610
MESH:D009101 Multiple Myeloma Raloxifene 3.4616497877
MESH:D009135 Muscular Diseases pirinixic acid 3.5516239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1519151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0412213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9716411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.5317484760
MESH:D009232 Myxoma Raloxifene 5.6216343187
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 13.733581430
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 13.733581430 9029167
MESH:D009362 Neoplasm Metastasis quinoline 13.73598648
MESH:D009362 Neoplasm Metastasis Tamoxifen 13.7319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5219410462
MESH:D009369 Neoplasms pirinixic acid 1.9617405874
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.0619196722 19189210 19200415
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2514600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 2.936679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.2618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.2620387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.1820387270
MESH:D009765 Obesity pirinixic acid 1.8220558911
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.454026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.083988306
MESH:D010018 Osteomalacia Phenobarbital 4.4117016548
MESH:D010024 Osteoporosis Raloxifene 3.4117882678 19059307 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.2617893378 15579764 17823083 15758505
MESH:D010146 Pain Acetaminophen 2.4116870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.2916540662
MESH:D010190 Pancreatic Neoplasms Phenobarbital 5.2916965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7211578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.527296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.536228378
MESH:D010954 Plasmacytoma Selenium 4.9515087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 9.172563599
MESH:D011230 Precancerous Conditions Phenobarbital 9.172563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2411399792 11896295 11118676 11222880
MESH:D011471 Prostatic Neoplasms Raloxifene 2.6216220300 16536755 15731164
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.6215067354
MESH:D011471 Prostatic Neoplasms Vitamin E 2.6215084515
MESH:D011537 Pruritus Ethinyl Estradiol 3.3616919318 15861022
MESH:D019310 Pseudolymphoma Phenobarbital 4.5612752131
MESH:D011693 Purpura Raloxifene 5.6215770314
MESH:D015427 Reperfusion Injury pirinixic acid 2.4019058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.393692021
MESH:D012640 Seizures Phenobarbital 2.713137016 4039156 11442880 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.876407741
MESH:D012871 Skin Diseases Vitamin E 2.4518709164
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 5.638532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.6316192470
MESH:D013088 Spermatocele Ethinyl Estradiol 11.7716709447
MESH:D013088 Spermatocele Tamoxifen 11.7716709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.0919457130
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D020521 Stroke Raloxifene 8.7816837676
MESH:D020521 Stroke Vitamin E 8.7816517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 12.086587162 6582329 7505956 3712494 1399818
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 12.087505956
MESH:D013964 Thyroid Neoplasms Phenobarbital 12.081399818
MESH:D013978 Tibial Fractures Raloxifene 5.2719048282
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.428074119
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 8.4217572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.4216712894 8653321 17572228
MESH:D014581 Urticaria Acetaminophen 3.0110982225
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3314692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D054556 Venous Thromboembolism Raloxifene 5.2716837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5714671159 15869587
MESH:D014846 Vulvar Neoplasms Raloxifene 5.6216343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
Pathway ID Pathway Name
REACT:604 Hemostasis
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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