AutismKB 2.0

Annotation Detail for THRAP3


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Basic Information Top
Gene Symbol:THRAP3 ( FLJ22082,MGC133082,MGC133083,TRAP150 )
Gene Full Name: thyroid hormone receptor associated protein 3
Band: 1p34.3
Quick LinksEntrez ID:9967; OMIM: 603809; Uniprot ID:TR150_HUMAN; ENSEMBL ID: ENSG00000054118; HGNC ID: 22964
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of THRAP3 mRNAaffects expression 17331233
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of THRAP3 mRNAaffects cotreatment|increases expression 17183730
C051890 irinotecan irinotecan analog results in decreased expression of THRAP3 mRNAdecreases expression 18927307
C006253 pirinixic acid pirinixic acid results in increased expression of THRAP3 mRNAincreases expression 16985257
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of THRAP3 mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 4.028875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 4.3019490988
MESH:D055371 Acute Lung Injury pirinixic acid 3.5218653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.0216434500
MESH:D000550 Amblyopia Valproic Acid 5.8517688650
MESH:D001008 Anxiety Disorders Valproic Acid 3.8617497229
MESH:D001321 Autistic Disorder Valproic Acid 1.9815238991 18316065 16609825 18396377 20603192 19460635 18558336 17507914 18775368 17157402 18940202 19232924 18177632 17688650 18985861
MESH:D001714 Bipolar Disorder Valproic Acid 3.2320046352 17594078
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.5219483382
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.618888407
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.8120734317
MESH:D002779 Cholestasis pirinixic acid 3.0819176532
MESH:D003110 Colonic Neoplasms irinotecan 2.6417287894 17725105
MESH:D015179 Colorectal Neoplasms irinotecan 2.3616391804 15273666 18509181 17454858 16303861 18259882 17159606
MESH:D019465 Craniofacial Abnormalities Valproic Acid 1.9017688650 8888407 16575769
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5618249437
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 2.2519641884 1733752
MESH:D004421 Dystonia Valproic Acid 4.451851702
MESH:D004487 Edema pirinixic acid 2.8512083418
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 4.643659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 4.5316628512 3922381
MESH:D004827 Epilepsy Valproic Acid 3.0920417680 18234410
MESH:D004832 Epilepsy, Absence Valproic Acid 3.917562514 6254150 6426943
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 4.787750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 4.603659116
MESH:D005234 Fatty Liver pirinixic acid 8.9920131406 19236843
MESH:D005234 Fatty Liver Valproic Acid 8.9919224547 14986274
MESH:D005315 Fetal Diseases Valproic Acid 5.5016575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 4.578888407 18558336
MESH:D006333 Heart Failure pirinixic acid 2.7320558911
MESH:D006529 Hepatomegaly pirinixic acid 3.4816221962 19772884 18467677 19176532
MESH:D006849 Hydrocephalus Valproic Acid 5.4117688650
MESH:D006943 Hyperglycemia pirinixic acid 3.5320558911
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 5.1116612254
MESH:D007333 Insulin Resistance pirinixic acid 2.8516306350
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1916294345 17596541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 1.9216377806 15890375 20007298
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 4.8717228818
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.5017365036
MESH:D008654 Mesothelioma Asbestos, Crocidolite 3.3016966607 18303189 16166281
MESH:D008881 Migraine Disorders Valproic Acid 3.4418803445 18765137
MESH:D052016 Mucositis irinotecan 5.5517159606
MESH:D009135 Muscular Diseases pirinixic acid 3.9916239165
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 4.408888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 3.3317596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.2619151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2216411023
MESH:D009362 Neoplasm Metastasis irinotecan 3.2818259882
MESH:D009369 Neoplasms pirinixic acid 2.0917405874
MESH:D009436 Neural Tube Defects Valproic Acid 3.348888407 16359493
MESH:D009447 Neuroblastoma irinotecan 3.648761367
MESH:D017599 Neuroectodermal Tumors irinotecan 5.278761367
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.3810923243
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 4.3720603192
MESH:D019310 Pseudolymphoma Valproic Acid 5.1512752131 11422049
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.1417322281 17365031 15814490 17975199
MESH:D015427 Reperfusion Injury pirinixic acid 2.5319058328
MESH:D012208 Rhabdomyosarcoma Valproic Acid 4.5819155313
MESH:D012559 Schizophrenia Valproic Acid 2.1019110320 15737665
MESH:D012640 Seizures Valproic Acid 2.9617978042 14763951 3137016 16876388 15475178 1511512 11044598 11738929
MESH:D016135 Spinal Dysraphism Valproic Acid 4.0619490988
MESH:D013226 Status Epilepticus Valproic Acid 5.1512833885
MESH:D013274 Stomach Neoplasms irinotecan 2.3615723263
MESH:D014178 Translocation, Genetic Valproic Acid 5.8517262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 5.063119515
MESH:D014564 Urogenital Abnormalities Valproic Acid 5.138888407
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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