AutismKB 2.0

Annotation Detail for RCE1


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Basic Information Top
Gene Symbol:RCE1 ( FACE2,RCE1A,RCE1B )
Gene Full Name: RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
Band: 11q13.2
Quick LinksEntrez ID:9986; OMIM: 605385; Uniprot ID:FACE2_HUMAN; ENSEMBL ID: ENSG00000173653; HGNC ID: 13721
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of RCE1 mRNAaffects expression 21346803
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of RCE1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of RCE1 mRNAincreases expression 19482888
C034028 vanadyl sulfate vanadyl sulfate results in increased expression of RCE1 mRNAincreases expression 16330358
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 4.186195326
MESH:D018248 Adenoma, Liver Cell Phenobarbital 4.7117620307
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 3.1716705839
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 3.1717173139 20935162 20007298 1701930 6705139
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.904080065
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.6718551238
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 4.7616684804
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 2.0618551238 21346803
MESH:D004421 Dystonia Phenobarbital 4.531851702
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.763659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.7411558140 3922381
MESH:D004827 Epilepsy Phenobarbital 3.0820417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.966401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.907750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.763659116
MESH:D006529 Hepatomegaly Phenobarbital 4.1316109766
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.3616705839
MESH:D008103 Liver Cirrhosis Phenobarbital 3.1021047994
MESH:D008107 Liver Diseases Phenobarbital 2.2519363144
MESH:D008113 Liver Neoplasms Phenobarbital 2.4319812893 21047994 19482888 15975961 8742319 19073162
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 2.9518308698 6150874 1399818 2563599 17172636
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 5.2217484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.6018551238
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.8816049721 12819281
MESH:D010018 Osteomalacia Phenobarbital 5.1117016548
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.6116965848
MESH:D011230 Precancerous Conditions Phenobarbital 4.042563599
MESH:D019310 Pseudolymphoma Phenobarbital 5.3612752131
MESH:D012640 Seizures 2,4-dinitrotoluene 6.9018551238
MESH:D012640 Seizures Phenobarbital 6.903137016 16876388 4039156 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 5.566407741
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.391399818
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.4216049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 5.0610091137
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018