Annotation Detail for ADA
Basic Information Top
| Gene Symbol: | ADA ( - ) |
|---|---|
| Gene Full Name: | adenosine deaminase |
| Band: | 20q13.12 |
| Quick Links | Entrez ID:100; OMIM: 608958; Uniprot ID:ADA_HUMAN; ENSEMBL ID: ENSG00000196839; HGNC ID: 186 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.654536
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 3 / 62319 | 48 | |
| fetus | 5 / 564012 | 8 |  |
| neonate | 2 / 31097 | 64 |  |
| infant | 0 / 23620 | 0 | |
| juvenile | 47 / 55556 | 845 |  |
| adult | 32 / 1939121 | 16 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 5 / 94178 | 53 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 21 / 263845 | 79 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 48 / 95842 | 500 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 3 / 103127 | 29 | |
| lymphoma | 6 / 71755 | 83 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 61 / 3360307 | 18 | |
| ovarian tumor | 2 / 76682 | 26 | |
| pancreatic tumor | 7 / 104616 | 66 | |
| primitive neuroectodermal tumor of the CNS | 4 / 125680 | 31 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 3 / 46356 | 64 | |
| skin tumor | 7 / 124949 | 56 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 49 / 123478 | 396 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 16 / 1100989 | 14 | |
| cervix | 7 / 48171 | 145 | |
| connective tissue | 3 / 149255 | 20 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 8 / 215722 | 37 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 7 / 211054 | 33 | |
| heart | 1 / 89626 | 11 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 2 / 211777 | 9 | |
| larynx | 0 / 24145 | 0 | |
| liver | 5 / 207743 | 24 | |
| lung | 5 / 336974 | 14 | |
| lymph | 3 / 44270 | 67 | |
| lymph node | 15 / 91610 | 163 | |
| mammary gland | 5 / 153271 | 32 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 7 / 214812 | 32 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 7 / 280825 | 24 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 7 / 210574 | 33 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 0 / 96619 | 0 | |
| testis | 6 / 330442 | 18 | |
| thymus | 7 / 81131 | 86 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 204639_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 234.15 | |
| Adipocyte | 6.7 | |
| AdrenalCortex | 3.95 | |
| Adrenalgland | 3.2 | |
| Amygdala | 4.15 | |
| Appendix | 3.9 | |
| AtrioventricularNode | 2.9 | |
| BDCA4+_DentriticCells | 326.1 | |
| Bonemarrow | 5.3 | |
| BronchialEpithelialCells | 26.45 | |
| CD105+_Endothelial | 12.9 | |
| CD14+_Monocytes | 6.25 | |
| CD19+_BCells(neg._sel.) | 4.25 | |
| CD33+_Myeloid | 8.9 | |
| CD34+ | 181.65 | |
| CD4+_Tcells | 36.95 | |
| CD56+_NKCells | 132.5 | |
| CD71+_EarlyErythroid | 3.7 | |
| CD8+_Tcells | 46.05 | |
| CardiacMyocytes | 5.1 | |
| Caudatenucleus | 3.5 | |
| Cerebellum | 3.15 | |
| CerebellumPeduncles | 4.35 | |
| CiliaryGanglion | 2.75 | |
| CingulateCortex | 3.95 | |
| Colorectaladenocarcinoma | 4.75 | |
| DorsalRootGanglion | 2.9 | |
| FetalThyroid | 3.45 | |
| Fetalbrain | 3.75 | |
| Fetalliver | 3.3 | |
| Fetallung | 3.65 | |
| GlobusPallidus | 2.8 | |
| Heart | 6.2 | |
| Hypothalamus | 4.15 | |
| Kidney | 3.1 | |
| Leukemia_chronicMyelogenousK-562 | 3.95 | |
| Leukemia_promyelocytic-HL-60 | 11.85 | |
| Leukemialymphoblastic(MOLT-4) | 1367.9 |  |
| Liver | 5.05 | |
| Lung | 4.3 | |
| Lymphnode | 5.85 | |
| Lymphoma_burkitts(Daudi) | 17.7 | |
| Lymphoma_burkitts(Raji) | 439.35 | |
| MedullaOblongata | 3.6 | |
| OccipitalLobe | 3.5 | |
| OlfactoryBulb | 3.05 | |
| Ovary | 2.55 | |
| Pancreas | 3.15 | |
| PancreaticIslet | 4.2 | |
| ParietalLobe | 4 | |
| Pituitary | 4.5 | |
| Placenta | 4.05 | |
| Pons | 3.95 | |
| PrefrontalCortex | 4.85 | |
| Prostate | 6.9 | |
| Salivarygland | 4.1 | |
| SkeletalMuscle | 4.35 | |
| Skin | 3 | |
| SmoothMuscle | 6.65 | |
| Spinalcord | 3.95 | |
| SubthalamicNucleus | 3.45 | |
| SuperiorCervicalGanglion | 4.35 | |
| TemporalLobe | 3.95 | |
| Testis | 3.4 | |
| TestisGermCell | 3.25 | |
| TestisIntersitial | 3.2 | |
| TestisLeydigCell | 4.1 | |
| TestisSeminiferousTubule | 3.3 | |
| Thalamus | 4 | |
| Thymus | 866 | |
| Thyroid | 4.95 | |
| Tongue | 3.75 | |
| Tonsil | 8.15 | |
| Trachea | 3.25 | |
| TrigeminalGanglion | 3.75 | |
| Uterus | 3.2 | |
| UterusCorpus | 3.55 | |
| WholeBlood | 10.4 | |
| Wholebrain | 3.4 | |
| colon | 3.9 | |
| pineal_day | 4.4 | |
| pineal_night | 4.26 | |
| retina | 4.7 | |
| small_intestine | 67.55 | |
- Probe name: A_23_P210482
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.16 ± 0.38 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 7.33 ± 0.24 | |
| Basal Part of Pons | 6.75 ± 0.36 | |
| Cerebellar Cortex | 6.45 ± 0.4 | |
| Cerebellar Nuclei | 7.88 ± 0.3 | |
| Claustrum | 6.45 ± 0.7 | |
| Epithalamus | 6.42 ± 0.78 | |
| Frontal Lobe | 7.17 ± 0.5 | |
| Globus Pallidus | 7.56 ± 0.47 | |
| Hypothalamus | 6.43 ± 0.37 | |
| Insula | 7.2 ± 0.39 | |
| Limbic Lobe | 6.97 ± 0.85 | |
| Mesencephalon | 7.04 ± 0.62 | |
| Myelencephalon | 7.15 ± 0.73 | |
| Occipital Lobe | 6.71 ± 0.54 | |
| Parietal Lobe | 7.07 ± 0.53 | |
| Pontine Tegmentum | 7.41 ± 0.65 | |
| Striatum | 8.23 ± 0.58 | |
| Subthalamus | 6.9 ± 0.5 | |
| Temporal Lobe | 7.12 ± 0.41 | |
| Thalamus | 7.29 ± 0.5 | |
| White Matter | 8.57 ± 0.13 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ada | CB | Cerebellum | 2.77 | |
| 3.11 | | |||
| Ada | CTX | Cerebral cortex | 2.03 | |
| 1.36 | | |||
| Ada | HIP | Hippocampal region | 1.75 | |
| 1.62 | | |||
| Ada | HPF | Hippocampal formation | 2.4 | |
| 1.99 | | |||
| Ada | HY | Hypothalamus | 0.16 | |
| 0.14 | | |||
| Ada | LSX | Lateral septal complex | 0.07 | |
| 0.07 | | |||
| Ada | MB | Midbrain | 0.36 | |
| 0.82 | | |||
| Ada | MY | Medulla | 0.52 | |
| 0.77 | | |||
| Ada | OLF | Olfactory bulb | 1.59 | |
| 1.22 | | |||
| Ada | P | Pons | 0.61 | |
| 1.61 | | |||
| Ada | PAL | Pallidum | 0.25 | |
| 0.27 | | |||
| Ada | RHP | Retrohippocampal region | 3.68 | |
| 2.66 | | |||
| Ada | sAMY | Striatum-like amygdalar nuclei | 2.51 | |
| 1.95 | | |||
| Ada | STR | Striatum | 1.51 | |
| 1.05 | | |||
| Ada | STRd | Striatum dorsal region | 1.93 | |
| 1.34 | | |||
| Ada | STRv | Striatum ventral region | 0.2 | |
| 0.12 | | |||
| Ada | TH | Thalamus | 0.42 | |
| 0.38 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| ADA_HUMAN_301 | 11 | 301 | 311 | STLDTDYQMTK | PRIDE |
| PAp00130908 | 31 | 112 | 142 | VEPIPWNQAEGDLTPDEVVALVGQGLQEGER | Peptide Atlas |