AutismKB 2.0

Annotation Detail for KCNE3


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Basic Information Top
Gene Symbol:KCNE3 ( DKFZp781H21101,HOKPP,HYPP,MGC102685,MGC129924,MiRP2 )
Gene Full Name: potassium voltage-gated channel, Isk-related family, member 3
Band: 11q13.4
Quick LinksEntrez ID:10008; OMIM: 604433; Uniprot ID:KCNE3_HUMAN; ENSEMBL ID: ENSG00000175538; HGNC ID: 6243
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus4 / 5640127
neonate2 / 3109764
infant0 / 236200 
juvenile5 / 5555689
adult38 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor11 / 26384541
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal57 / 336030716
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites3 / 4001574
bladder0 / 297570 
blood7 / 12347856
bone0 / 716550 
bone marrow2 / 4880140
brain8 / 11009897
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye5 / 21105423
heart0 / 896260 
intestine12 / 23447251
kidney9 / 21177742
larynx0 / 241450 
liver0 / 2077430 
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta7 / 28082524
prostate5 / 18934526
salivary gland0 / 201550 
skin0 / 2105740 
spleen2 / 5395237
stomach14 / 96619144
testis2 / 3304426
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14169_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.86 ± 0.97
Basal Forebrain1.19 ± 0.22
Basal Part of Pons1.17 ± 0.45
Cerebellar Cortex1.13 ± 0.51
Cerebellar Nuclei1.67 ± 0.65
Claustrum2.21 ± 0.8
Epithalamus1.44 ± 0.76
Frontal Lobe1.4 ± 0.75
Globus Pallidus2.32 ± 0.79
Hypothalamus1.41 ± 0.75
Insula1.19 ± 0.63
Limbic Lobe1.48 ± 0.67
Mesencephalon1.6 ± 0.79
Myelencephalon1.48 ± 0.66
Occipital Lobe1.63 ± 0.78
Parietal Lobe1.37 ± 0.75
Pontine Tegmentum1.55 ± 0.73
Striatum1.7 ± 0.61
Subthalamus1.65 ± 0.41
Temporal Lobe1.41 ± 0.69
Thalamus1.42 ± 0.67
White Matter2.05 ± 0.57
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Kcne3CBCerebellum5.59
4.89
Kcne3CTXCerebral cortex4.3
2.95
Kcne3HIPHippocampal region10.89
4.41
Kcne3HPFHippocampal formation9.08
4.96
Kcne3HYHypothalamus1.29
0.8
Kcne3LSXLateral septal complex2.18
2.8
Kcne3MBMidbrain1.93
1.53
Kcne3MYMedulla2.89
3.17
Kcne3OLFOlfactory bulb6.47
3.45
Kcne3PPons3.69
3.09
Kcne3PALPallidum0.29
0.23
Kcne3RHPRetrohippocampal region6.14
5.04
Kcne3sAMYStriatum-like amygdalar nuclei2.25
1.33
Kcne3STRStriatum0.99
0.68
Kcne3STRdStriatum dorsal region0.17
0.11
Kcne3STRvStriatum ventral region3.08
1.73
Kcne3THThalamus1.42
0.83
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018