AutismKB 2.0

Annotation Detail for CDH3


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Basic Information Top
Gene Symbol:CDH3 ( CDHP,HJMD,PCAD )
Gene Full Name: cadherin 3, type 1, P-cadherin (placental)
Band: 16q22.1
Quick LinksEntrez ID:1001; OMIM: 114021; Uniprot ID:CADH3_HUMAN; ENSEMBL ID: ENSG00000062038; HGNC ID: 1762
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body15 / 70761211
blastocyst11 / 62319176
fetus12 / 56401221
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult91 / 193912146
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor5 / 11424643
esophageal tumor3 / 17290173
gastrointestinal tumor1 / 1193698
germ cell tumor11 / 26384541
glioma2 / 10688318
head and neck tumor37 / 136302271
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal118 / 336030735
ovarian tumor5 / 7668265
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer14 / 102680136
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder3 / 29757100
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain14 / 110098912
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue36 / 215722166
esophagus3 / 20209148
eye9 / 21105442
heart7 / 8962678
intestine13 / 23447255
kidney4 / 21177718
larynx5 / 24145207
liver1 / 2077434
lung13 / 33697438
lymph0 / 442700 
lymph node0 / 916100 
mammary gland13 / 15327184
mouth31 / 67052462
muscle1 / 1077159
nerve0 / 157680 
ovary8 / 10205178
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta13 / 28082546
prostate21 / 189345110
salivary gland0 / 201550 
skin13 / 21057461
spleen2 / 5395237
stomach2 / 9661920
testis17 / 33044251
thymus39 / 81131480
thyroid4 / 4747384
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus19 / 23287881
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203256_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.15
Adipocyte4
AdrenalCortex4.25
Adrenalgland3.4
Amygdala4.3
Appendix4.1
AtrioventricularNode3.05
BDCA4+_DentriticCells4.5
Bonemarrow4
BronchialEpithelialCells955.2
CD105+_Endothelial4.15
CD14+_Monocytes4.35
CD19+_BCells(neg._sel.)4.3
CD33+_Myeloid5.2
CD34+5.2
CD4+_Tcells4.4
CD56+_NKCells4.9
CD71+_EarlyErythroid3.8
CD8+_Tcells3.9
CardiacMyocytes5.25
Caudatenucleus3.6
Cerebellum3.3
CerebellumPeduncles4.55
CiliaryGanglion2.9
CingulateCortex4.2
Colorectaladenocarcinoma5.7
DorsalRootGanglion3.1
FetalThyroid4
Fetalbrain4.1
Fetalliver3.5
Fetallung4.15
GlobusPallidus2.95
Heart5.1
Hypothalamus4.4
Kidney3.3
Leukemia_chronicMyelogenousK-5623.7
Leukemia_promyelocytic-HL-603.6
Leukemialymphoblastic(MOLT-4)3.25
Liver5.35
Lung4.5
Lymphnode3.5
Lymphoma_burkitts(Daudi)5.2
Lymphoma_burkitts(Raji)5.7
MedullaOblongata3.75
OccipitalLobe3.7
OlfactoryBulb3.2
Ovary2.7
Pancreas3.3
PancreaticIslet4.35
ParietalLobe4.3
Pituitary4.75
Placenta4.25
Pons3.9
PrefrontalCortex5
Prostate14.1
Salivarygland3.55
SkeletalMuscle4.65
Skin3.1
SmoothMuscle4.6
Spinalcord4.3
SubthalamicNucleus3.7
SuperiorCervicalGanglion4.6
TemporalLobe3.75
Testis3.5
TestisGermCell3.6
TestisIntersitial3.4
TestisLeydigCell4.05
TestisSeminiferousTubule3.5
Thalamus4.15
Thymus36.75
Thyroid5.05
Tongue4
Tonsil4.65
Trachea4
TrigeminalGanglion4.05
Uterus4.2
UterusCorpus4.5
WholeBlood4.45
Wholebrain3.5
colon4.1
pineal_day5.06
pineal_night4.94
retina12.025
small_intestine3.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15619_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.55 ± 0.69
Basal Forebrain2.87 ± 0.31
Basal Part of Pons3.11 ± 0.52
Cerebellar Cortex3.15 ± 0.61
Cerebellar Nuclei2.9 ± 0.59
Claustrum3.64 ± 0.97
Epithalamus2.43 ± 0.56
Frontal Lobe3.03 ± 0.67
Globus Pallidus3.1 ± 0.7
Hypothalamus2.88 ± 0.82
Insula2.79 ± 0.67
Limbic Lobe3.21 ± 0.64
Mesencephalon3.06 ± 0.66
Myelencephalon3.19 ± 0.66
Occipital Lobe3.09 ± 0.77
Parietal Lobe3.08 ± 0.66
Pontine Tegmentum2.91 ± 0.7
Striatum2.99 ± 0.77
Subthalamus2.92 ± 0.59
Temporal Lobe3.09 ± 0.67
Thalamus3.08 ± 0.53
White Matter4.12 ± 1.91
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdh3CBCerebellum2.45
2.9
Cdh3CTXCerebral cortex0.95
0.94
Cdh3HIPHippocampal region1.09
0.85
Cdh3HPFHippocampal formation0.76
0.56
Cdh3HYHypothalamus0.63
0.69
Cdh3LSXLateral septal complex0.24
0.23
Cdh3MBMidbrain0.26
0.31
Cdh3MYMedulla2.59
2.68
Cdh3OLFOlfactory bulb1.54
1.38
Cdh3PPons0.75
1.12
Cdh3PALPallidum0.16
0.19
Cdh3RHPRetrohippocampal region0.14
0.12
Cdh3sAMYStriatum-like amygdalar nuclei0.19
0.19
Cdh3STRStriatum0.56
0.6
Cdh3STRdStriatum dorsal region0.57
0.65
Cdh3STRvStriatum ventral region0.78
0.67
Cdh3THThalamus1.69
1.03
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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