AutismKB 2.0

Annotation Detail for TROAP


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Basic Information Top
Gene Symbol:TROAP ( TASTIN )
Gene Full Name: trophinin associated protein (tastin)
Band: 12q13.12
Quick LinksEntrez ID:10024; OMIM: 603872; Uniprot ID:TROAP_HUMAN; ENSEMBL ID: ENSG00000135451; HGNC ID: 12327
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst9 / 62319144
fetus36 / 56401263
neonate1 / 3109732
infant1 / 2362042
juvenile3 / 5555653
adult36 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor5 / 34366145
chondrosarcoma1 / 8282312
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor10 / 26384537
glioma11 / 106883102
head and neck tumor4 / 13630229
kidney tumor4 / 6895958
leukemia8 / 9584283
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma5 / 7175569
non-neoplasia1 / 9725010
normal92 / 336030727
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS19 / 125680151
prostate cancer9 / 10268087
retinoblastoma6 / 46356129
skin tumor18 / 124949144
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood6 / 12347848
bone1 / 7165513
bone marrow4 / 4880181
brain19 / 110098917
cervix8 / 48171166
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue18 / 21572283
esophagus0 / 202090 
eye9 / 21105442
heart3 / 8962633
intestine13 / 23447255
kidney5 / 21177723
larynx0 / 241450 
liver5 / 20774324
lung7 / 33697420
lymph5 / 44270112
lymph node5 / 9161054
mammary gland4 / 15327126
mouth3 / 6705244
muscle2 / 10771518
nerve1 / 1576863
ovary3 / 10205129
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate9 / 18934547
salivary gland0 / 201550 
skin18 / 21057485
spleen1 / 5395218
stomach4 / 9661941
testis15 / 33044245
thymus48 / 81131591
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus13 / 23287855
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204649_at
Cell line Expression level Expression bar
721_B_lymphoblasts29.6
Adipocyte5.8
AdrenalCortex6.5
Adrenalgland4.95
Amygdala5.9
Appendix5.95
AtrioventricularNode4.85
BDCA4+_DentriticCells5.75
Bonemarrow6.25
BronchialEpithelialCells5.75
CD105+_Endothelial26.9
CD14+_Monocytes6
CD19+_BCells(neg._sel.)5.95
CD33+_Myeloid7.4
CD34+21.1
CD4+_Tcells6.3
CD56+_NKCells6.35
CD71+_EarlyErythroid21
CD8+_Tcells5.3
CardiacMyocytes10.25
Caudatenucleus5.3
Cerebellum5.15
CerebellumPeduncles6.75
CiliaryGanglion4.2
CingulateCortex6.05
Colorectaladenocarcinoma10.45
DorsalRootGanglion4.55
FetalThyroid5.65
Fetalbrain5.8
Fetalliver5.35
Fetallung5
GlobusPallidus4.35
Heart7.5
Hypothalamus6.1
Kidney5.05
Leukemia_chronicMyelogenousK-5626.75
Leukemia_promyelocytic-HL-608.05
Leukemialymphoblastic(MOLT-4)17.35
Liver7.7
Lung6.25
Lymphnode5.6
Lymphoma_burkitts(Daudi)16.85
Lymphoma_burkitts(Raji)8.2
MedullaOblongata5.65
OccipitalLobe5.4
OlfactoryBulb4.75
Ovary3.95
Pancreas5.05
PancreaticIslet6.3
ParietalLobe6.4
Pituitary6.95
Placenta5.9
Pons5.6
PrefrontalCortex6.95
Prostate6.7
Salivarygland4.7
SkeletalMuscle7.4
Skin4.5
SmoothMuscle6.5
Spinalcord6.4
SubthalamicNucleus5.35
SuperiorCervicalGanglion7.1
TemporalLobe5.35
Testis17.8
TestisGermCell9.6
TestisIntersitial8.55
TestisLeydigCell8.2
TestisSeminiferousTubule9.2
Thalamus6.05
Thymus9.75
Thyroid6.9
Tongue5.85
Tonsil7.1
Trachea5
TrigeminalGanglion6.2
Uterus4.6
UterusCorpus5.85
WholeBlood6.4
Wholebrain4.9
colon6.05
pineal_day7.1
pineal_night6.92
retina7.025
small_intestine5.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6125_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.3 ± 1.12
Basal Forebrain2.1 ± 0.68
Basal Part of Pons1.7 ± 0.78
Cerebellar Cortex1.97 ± 0.85
Cerebellar Nuclei2.32 ± 0.73
Claustrum2.85 ± 0.95
Epithalamus1.43 ± 0.75
Frontal Lobe1.8 ± 0.73
Globus Pallidus2.36 ± 0.51
Hypothalamus1.89 ± 0.81
Insula1.8 ± 0.75
Limbic Lobe1.87 ± 0.72
Mesencephalon2.04 ± 0.73
Myelencephalon1.92 ± 0.69
Occipital Lobe2.09 ± 0.87
Parietal Lobe1.95 ± 0.75
Pontine Tegmentum2 ± 0.75
Striatum1.98 ± 0.77
Subthalamus2 ± 0.74
Temporal Lobe1.8 ± 0.75
Thalamus1.78 ± 0.65
White Matter2.13 ± 0.23
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
TROAP_HUMAN_5 9 5 13 QATKDPLLR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018