AutismKB 2.0

Annotation Detail for ARHGEF33


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Basic Information Top
Gene Symbol:ARHGEF33 ( FLJ41381 )
Gene Full Name: Rho guanine nucleotide exchange factor (GEF) 33
Band: 2p22.1
Quick LinksEntrez ID:100271715; OMIM: NA; Uniprot ID:; ENSEMBL ID: ENSG00000214694; HGNC ID: 37252
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus15 / 56401226
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult31 / 193912115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal100 / 336030729
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder1 / 2975733
blood1 / 1234788
bone0 / 716550 
bone marrow1 / 4880120
brain16 / 110098914
cervix0 / 481710 
connective tissue0 / 1492550 
ear1 / 1621261
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart3 / 8962633
intestine3 / 23447212
kidney17 / 21177780
larynx0 / 241450 
liver0 / 2077430 
lung18 / 33697453
lymph0 / 442700 
lymph node3 / 9161032
mammary gland2 / 15327113
mouth1 / 6705214
muscle2 / 10771518
nerve1 / 1576863
ovary2 / 10205119
pancreas2 / 2148129
parathyroid7 / 20539340
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach0 / 966190 
testis14 / 33044242
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1070_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.1 ± 0.44
Basal Forebrain5.59 ± 0.53
Basal Part of Pons5.47 ± 0.5
Cerebellar Cortex6.41 ± 0.35
Cerebellar Nuclei5.33 ± 0.39
Claustrum5.96 ± 0.63
Epithalamus5.97 ± 0.76
Frontal Lobe5.55 ± 0.63
Globus Pallidus5.16 ± 0.41
Hypothalamus5.54 ± 0.5
Insula5.93 ± 0.31
Limbic Lobe5.91 ± 0.44
Mesencephalon5.88 ± 0.47
Myelencephalon5.75 ± 0.57
Occipital Lobe5.99 ± 0.45
Parietal Lobe5.88 ± 0.45
Pontine Tegmentum5.74 ± 0.59
Striatum5.38 ± 0.3
Subthalamus5.69 ± 0.43
Temporal Lobe5.93 ± 0.41
Thalamus5.71 ± 0.57
White Matter5.12 ± 0.43
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018