AutismKB 2.0

Annotation Detail for CDH5


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Basic Information Top
Gene Symbol:CDH5 ( 7B4,CD144,FLJ17376 )
Gene Full Name: cadherin 5, type 2 (vascular endothelium)
Band: 16q21
Quick LinksEntrez ID:1003; OMIM: 601120; Uniprot ID:CADH5_HUMAN; ENSEMBL ID: ENSG00000179776; HGNC ID: 1764
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus30 / 56401253
neonate2 / 3109764
infant0 / 236200 
juvenile2 / 5555635
adult170 / 193912187
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor5 / 26384518
glioma2 / 10688318
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal243 / 336030772
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain43 / 110098939
cervix0 / 481710 
connective tissue6 / 14925540
ear1 / 1621261
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye1 / 2110544
heart4 / 8962644
intestine2 / 2344728
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth1 / 6705214
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta141 / 280825502
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach3 / 9661931
testis14 / 33044242
thymus4 / 8113149
thyroid8 / 47473168
tonsil0 / 169990 
trachea8 / 52413152
umbilical cord2 / 13680146
uterus17 / 23287872
vascular23 / 51780444
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204677_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.65
Adipocyte6.1
AdrenalCortex7.05
Adrenalgland11.2
Amygdala7.1
Appendix7.35
AtrioventricularNode5.15
BDCA4+_DentriticCells6.4
Bonemarrow6.6
BronchialEpithelialCells5.7
CD105+_Endothelial6.75
CD14+_Monocytes6.4
CD19+_BCells(neg._sel.)6.2
CD33+_Myeloid7.1
CD34+7.65
CD4+_Tcells6.15
CD56+_NKCells7.55
CD71+_EarlyErythroid5.45
CD8+_Tcells5.65
CardiacMyocytes107.9
Caudatenucleus5.9
Cerebellum5.3
CerebellumPeduncles7.55
CiliaryGanglion4.75
CingulateCortex6.95
Colorectaladenocarcinoma6.55
DorsalRootGanglion5.2
FetalThyroid18.25
Fetalbrain6.65
Fetalliver12.05
Fetallung314.8
GlobusPallidus4.75
Heart129.75
Hypothalamus7.25
Kidney7.5
Leukemia_chronicMyelogenousK-5625.95
Leukemia_promyelocytic-HL-605.85
Leukemialymphoblastic(MOLT-4)4.95
Liver8.75
Lung550.45
Lymphnode19.85
Lymphoma_burkitts(Daudi)8.4
Lymphoma_burkitts(Raji)9.3
MedullaOblongata5.95
OccipitalLobe6
OlfactoryBulb8.05
Ovary4.45
Pancreas5.85
PancreaticIslet7.45
ParietalLobe7
Pituitary7.8
Placenta837.75
Pons6.3
PrefrontalCortex13.95
Prostate8.35
Salivarygland5.3
SkeletalMuscle7.8
Skin6
SmoothMuscle23.9
Spinalcord7.9
SubthalamicNucleus5.7
SuperiorCervicalGanglion9.8
TemporalLobe6
Testis5.9
TestisGermCell5.6
TestisIntersitial5.4
TestisLeydigCell6.3
TestisSeminiferousTubule5.7
Thalamus8.35
Thymus9.25
Thyroid63.6
Tongue6.65
Tonsil6.45
Trachea7.85
TrigeminalGanglion6.8
Uterus12.95
UterusCorpus6
WholeBlood6.85
Wholebrain5.6
colon8.15
pineal_day8.76
pineal_night8.42
retina30.225
small_intestine24.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16978_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.53 ± 1.03
Basal Forebrain2.1 ± 0.51
Basal Part of Pons1.61 ± 0.34
Cerebellar Cortex1.72 ± 0.56
Cerebellar Nuclei2.34 ± 0.66
Claustrum2.89 ± 0.88
Epithalamus1.62 ± 0.88
Frontal Lobe1.94 ± 0.77
Globus Pallidus2.9 ± 0.93
Hypothalamus2.07 ± 0.72
Insula1.76 ± 0.34
Limbic Lobe2 ± 0.71
Mesencephalon2.27 ± 0.78
Myelencephalon2.07 ± 0.74
Occipital Lobe2.13 ± 0.63
Parietal Lobe1.97 ± 0.71
Pontine Tegmentum2.13 ± 0.71
Striatum2.48 ± 0.86
Subthalamus2.24 ± 0.5
Temporal Lobe1.96 ± 0.72
Thalamus2.05 ± 0.58
White Matter2.36 ± 0.56
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024951 17 432 448 ELDREVYPWYNLTVEAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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