AutismKB 2.0

Annotation Detail for CHAF1A


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CHAF1A ( CAF-1,CAF1,CAF1B,CAF1P150,MGC71229,P150 )
Gene Full Name: chromatin assembly factor 1, subunit A (p150)
Band: 19p13.3
Quick LinksEntrez ID:10036; OMIM: 601246; Uniprot ID:CAF1A_HUMAN; ENSEMBL ID: ENSG00000167670; HGNC ID: 1910
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst8 / 62319128
fetus19 / 56401233
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor28 / 263845106
glioma7 / 10688365
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor25 / 96359259
lung tumor10 / 10312796
lymphoma4 / 7175555
non-neoplasia1 / 9725010
normal76 / 336030722
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer12 / 102680116
retinoblastoma7 / 46356151
skin tumor4 / 12494932
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites3 / 4001574
bladder0 / 297570 
blood9 / 12347872
bone3 / 7165541
bone marrow3 / 4880161
brain11 / 11009899
cervix0 / 481710 
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye16 / 21105475
heart4 / 8962644
intestine9 / 23447238
kidney1 / 2117774
larynx1 / 2414541
liver27 / 207743129
lung13 / 33697438
lymph3 / 4427067
lymph node8 / 9161087
mammary gland3 / 15327119
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary6 / 10205158
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate14 / 18934573
salivary gland0 / 201550 
skin5 / 21057423
spleen0 / 539520 
stomach4 / 9661941
testis5 / 33044215
thymus1 / 8113112
thyroid1 / 4747321
tonsil1 / 1699958
trachea1 / 5241319
umbilical cord0 / 136800 
uterus7 / 23287830
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203976_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts80.85
Adipocyte9.3
AdrenalCortex11.65
Adrenalgland8.35
Amygdala9.65
Appendix9
AtrioventricularNode7.6
BDCA4+_DentriticCells117.65
Bonemarrow10.5
BronchialEpithelialCells8.75
CD105+_Endothelial30.2
CD14+_Monocytes27.65
CD19+_BCells(neg._sel.)10.1
CD33+_Myeloid12.35
CD34+46.95
CD4+_Tcells10.45
CD56+_NKCells9.7
CD71+_EarlyErythroid17.15
CD8+_Tcells8.45
CardiacMyocytes14.7
Caudatenucleus8.6
Cerebellum7.7
CerebellumPeduncles12.3
CiliaryGanglion9.85
CingulateCortex10
Colorectaladenocarcinoma22.15
DorsalRootGanglion10.7
FetalThyroid9.25
Fetalbrain9.35
Fetalliver9.2
Fetallung6.45
GlobusPallidus9.3
Heart13.3
Hypothalamus9.75
Kidney8.45
Leukemia_chronicMyelogenousK-56217.45
Leukemia_promyelocytic-HL-6014.5
Leukemialymphoblastic(MOLT-4)127.2
Liver12.65
Lung10.25
Lymphnode6.6
Lymphoma_burkitts(Daudi)27.7
Lymphoma_burkitts(Raji)15.1
MedullaOblongata8.6
OccipitalLobe8.5
OlfactoryBulb6.5
Ovary6.8
Pancreas7.6
PancreaticIslet10.2
ParietalLobe10.1
Pituitary11.15
Placenta9.7
Pons9.1
PrefrontalCortex11.7
Prostate11.2
Salivarygland7.8
SkeletalMuscle11.25
Skin7.35
SmoothMuscle10.5
Spinalcord10.15
SubthalamicNucleus7.7
SuperiorCervicalGanglion11.15
TemporalLobe8.75
Testis8.8
TestisGermCell8.65
TestisIntersitial8.1
TestisLeydigCell9.5
TestisSeminiferousTubule8.4
Thalamus9.7
Thymus9.3
Thyroid11.2
Tongue9.5
Tonsil10.65
Trachea7.75
TrigeminalGanglion9.5
Uterus7.4
UterusCorpus8.75
WholeBlood9.5
Wholebrain7.9
colon9.4
pineal_day11.54
pineal_night10.6
retina11.3
small_intestine9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9242_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.25 ± 0.8
Basal Forebrain3.8 ± 0.6
Basal Part of Pons4.58 ± 0.77
Cerebellar Cortex4.23 ± 0.54
Cerebellar Nuclei4.05 ± 0.61
Claustrum3.74 ± 1.14
Epithalamus4.21 ± 0.58
Frontal Lobe4.36 ± 0.55
Globus Pallidus4.57 ± 0.44
Hypothalamus3.96 ± 0.32
Insula4.04 ± 0.41
Limbic Lobe3.95 ± 0.59
Mesencephalon4.28 ± 0.66
Myelencephalon4.13 ± 0.57
Occipital Lobe3.87 ± 0.58
Parietal Lobe4.32 ± 0.54
Pontine Tegmentum4.03 ± 0.54
Striatum3.77 ± 0.61
Subthalamus4.55 ± 0.34
Temporal Lobe4.22 ± 0.56
Thalamus4.09 ± 0.62
White Matter4.11 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Chaf1aCBCerebellum7.03
7.31
Chaf1aCTXCerebral cortex6.08
4.33
Chaf1aHIPHippocampal region7.11
7.16
Chaf1aHPFHippocampal formation5.82
5.22
Chaf1aHYHypothalamus8.63
7.05
Chaf1aLSXLateral septal complex2.6
2.13
Chaf1aMBMidbrain4.81
5.01
Chaf1aMYMedulla3.93
4.34
Chaf1aOLFOlfactory bulb12.86
9.49
Chaf1aPPons11.39
11.77
Chaf1aPALPallidum3.83
3.41
Chaf1aRHPRetrohippocampal region3.31
2.29
Chaf1asAMYStriatum-like amygdalar nuclei3.36
2.41
Chaf1aSTRStriatum2.91
2.44
Chaf1aSTRdStriatum dorsal region1.51
1.6
Chaf1aSTRvStriatum ventral region7.22
4.92
Chaf1aTHThalamus6.88
5.51
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CAF1A_HUMAN_394 12 394 405 QEALEAKLEEKR PRIDE
PAp00031482 26 65 90 SPDLEASLDTLENNCHVGSDIDFRPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved