AutismKB 2.0

Annotation Detail for TOM1L1


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Basic Information Top
Gene Symbol:TOM1L1 ( OK/KNS-CL.3,SRCASM )
Gene Full Name: target of myb1 (chicken)-like 1
Band: 17q23.2
Quick LinksEntrez ID:10040; OMIM: 604701; Uniprot ID:TM1L1_HUMAN; ENSEMBL ID: ENSG00000141198; HGNC ID: 11983
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst5 / 6231980
fetus17 / 56401230
neonate2 / 3109764
infant2 / 2362084
juvenile5 / 5555689
adult72 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor9 / 11424678
esophageal tumor3 / 17290173
gastrointestinal tumor13 / 119369108
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor8 / 13630258
kidney tumor2 / 6895929
leukemia2 / 9584220
liver tumor5 / 9635951
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal125 / 336030737
ovarian tumor1 / 7668213
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites3 / 4001574
bladder6 / 29757201
blood1 / 1234788
bone7 / 7165597
bone marrow1 / 4880120
brain28 / 110098925
cervix0 / 481710 
connective tissue3 / 14925520
ear1 / 1621261
embryonic tissue9 / 21572241
esophagus3 / 20209148
eye9 / 21105442
heart3 / 8962633
intestine19 / 23447281
kidney26 / 211777122
larynx2 / 2414582
liver9 / 20774343
lung9 / 33697426
lymph0 / 442700 
lymph node1 / 9161010
mammary gland8 / 15327152
mouth4 / 6705259
muscle2 / 10771518
nerve1 / 1576863
ovary4 / 10205139
pancreas5 / 21481223
parathyroid5 / 20539243
pharynx2 / 4132848
pituitary gland1 / 1658560
placenta5 / 28082517
prostate7 / 18934536
salivary gland3 / 20155148
skin10 / 21057447
spleen1 / 5395218
stomach11 / 96619113
testis12 / 33044236
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea16 / 52413305
umbilical cord0 / 136800 
uterus17 / 23287872
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204485_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.4
Adipocyte7.35
AdrenalCortex10.25
Adrenalgland6.9
Amygdala7.6
Appendix9.45
AtrioventricularNode7.8
BDCA4+_DentriticCells7.95
Bonemarrow8
BronchialEpithelialCells63.7
CD105+_Endothelial7.75
CD14+_Monocytes8.05
CD19+_BCells(neg._sel.)7.8
CD33+_Myeloid9.35
CD34+9.3
CD4+_Tcells7.45
CD56+_NKCells8.3
CD71+_EarlyErythroid7.2
CD8+_Tcells6.55
CardiacMyocytes10.6
Caudatenucleus6.8
Cerebellum6.2
CerebellumPeduncles8.9
CiliaryGanglion7.45
CingulateCortex7.95
Colorectaladenocarcinoma8.85
DorsalRootGanglion6.65
FetalThyroid15.6
Fetalbrain7.35
Fetalliver9.15
Fetallung6.45
GlobusPallidus5.95
Heart11.25
Hypothalamus7.95
Kidney13.35
Leukemia_chronicMyelogenousK-5627.85
Leukemia_promyelocytic-HL-606.75
Leukemialymphoblastic(MOLT-4)5.9
Liver23.8
Lung8.3
Lymphnode6.35
Lymphoma_burkitts(Daudi)10.05
Lymphoma_burkitts(Raji)11.4
MedullaOblongata6.85
OccipitalLobe6.8
OlfactoryBulb5.95
Ovary5.15
Pancreas8.7
PancreaticIslet42.55
ParietalLobe8.9
Pituitary9
Placenta7.55
Pons7.5
PrefrontalCortex9.2
Prostate9.95
Salivarygland6.4
SkeletalMuscle12.4
Skin7.4
SmoothMuscle8.6
Spinalcord8.25
SubthalamicNucleus7.45
SuperiorCervicalGanglion12.55
TemporalLobe7.15
Testis6.5
TestisGermCell6.65
TestisIntersitial6.5
TestisLeydigCell8.05
TestisSeminiferousTubule6.55
Thalamus7.9
Thymus5.75
Thyroid30.8
Tongue8.35
Tonsil7.55
Trachea10.9
TrigeminalGanglion8.55
Uterus6.05
UterusCorpus7.4
WholeBlood8.2
Wholebrain6.05
colon19.85
pineal_day10.14
pineal_night15.38
retina9.275
small_intestine21.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P196658
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.11 ± 0.54
Basal Forebrain3.33 ± 0.52
Basal Part of Pons3.19 ± 0.49
Cerebellar Cortex3.57 ± 0.65
Cerebellar Nuclei3.26 ± 0.59
Claustrum4.19 ± 0.84
Epithalamus4.53 ± 0.18
Frontal Lobe3.93 ± 0.57
Globus Pallidus3.49 ± 0.65
Hypothalamus3.97 ± 0.73
Insula4.08 ± 0.37
Limbic Lobe3.58 ± 0.56
Mesencephalon3.85 ± 0.67
Myelencephalon3.77 ± 0.62
Occipital Lobe3.05 ± 0.65
Parietal Lobe3.58 ± 0.6
Pontine Tegmentum3.84 ± 0.63
Striatum3.03 ± 0.83
Subthalamus3.61 ± 0.37
Temporal Lobe3.91 ± 0.54
Thalamus3.78 ± 0.54
White Matter2.21 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tom1l1CBCerebellum4.15
6.69
Tom1l1CTXCerebral cortex4.47
3.88
Tom1l1HIPHippocampal region0.54
0.53
Tom1l1HPFHippocampal formation0.35
0.35
Tom1l1HYHypothalamus0.99
1.77
Tom1l1LSXLateral septal complex0.11
0.06
Tom1l1MBMidbrain0.74
1.23
Tom1l1MYMedulla0.33
0.5
Tom1l1OLFOlfactory bulb0.73
1.03
Tom1l1PPons0.13
0.22
Tom1l1PALPallidum0
0
Tom1l1RHPRetrohippocampal region0.04
0.08
Tom1l1sAMYStriatum-like amygdalar nuclei0.14
0.1
Tom1l1STRStriatum0.28
0.34
Tom1l1STRdStriatum dorsal region0.34
0.46
Tom1l1STRvStriatum ventral region0.16
0.1
Tom1l1THThalamus0.91
1.01
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00520821 24 302 325 EATNTTSEPSAPSQDLLDLSPSPR Peptide Atlas
TM1L1_HUMAN_2 7 2 8 AFGKSHR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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