AutismKB 2.0

Annotation Detail for ABCC5


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Basic Information Top
Gene Symbol:ABCC5 ( ABC33,DKFZp686C1782,EST277145,MOAT-C,MOATC,MRP5,SMRP,pABC11 )
Gene Full Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 5
Band: 3q27.1
Quick LinksEntrez ID:10057; OMIM: 605251; Uniprot ID:MRP5_HUMAN; ENSEMBL ID: ENSG00000114770; HGNC ID: 56
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209380_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.05
Adipocyte8.05
AdrenalCortex7.7
Adrenalgland6.75
Amygdala39.8
Appendix8.15
AtrioventricularNode5.6
BDCA4+_DentriticCells7.75
Bonemarrow10
BronchialEpithelialCells8.9
CD105+_Endothelial106.2
CD14+_Monocytes10.3
CD19+_BCells(neg._sel.)8.5
CD33+_Myeloid25.9
CD34+51.75
CD4+_Tcells22.8
CD56+_NKCells24.25
CD71+_EarlyErythroid120.45
CD8+_Tcells17.95
CardiacMyocytes9.75
Caudatenucleus46.4
Cerebellum23.8
CerebellumPeduncles25.2
CiliaryGanglion5.7
CingulateCortex40.35
Colorectaladenocarcinoma10.45
DorsalRootGanglion6.05
FetalThyroid7.6
Fetalbrain17.65
Fetalliver7.2
Fetallung10.15
GlobusPallidus10.95
Heart9.45
Hypothalamus54.05
Kidney6.9
Leukemia_chronicMyelogenousK-56211.45
Leukemia_promyelocytic-HL-608
Leukemialymphoblastic(MOLT-4)26.6
Liver7.65
Lung16.55
Lymphnode9.95
Lymphoma_burkitts(Daudi)10.8
Lymphoma_burkitts(Raji)16.85
MedullaOblongata33.3
OccipitalLobe32.3
OlfactoryBulb12.3
Ovary5.15
Pancreas6
PancreaticIslet9.85
ParietalLobe19
Pituitary21.35
Placenta8.05
Pons22.35
PrefrontalCortex87.95
Prostate19.15
Salivarygland6
SkeletalMuscle56.55
Skin4.1
SmoothMuscle9.85
Spinalcord18.45
SubthalamicNucleus10.5
SuperiorCervicalGanglion8.4
TemporalLobe13.5
Testis7.3
TestisGermCell33.45
TestisIntersitial5.35
TestisLeydigCell7.45
TestisSeminiferousTubule8.1
Thalamus22.3
Thymus17.55
Thyroid10.7
Tongue12.75
Tonsil8.35
Trachea7.1
TrigeminalGanglion4
Uterus25.4
UterusCorpus7.15
WholeBlood10
Wholebrain32.35
colon8.5
pineal_day51.22
pineal_night56.46
retina131.125
small_intestine7.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P212665
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.77 ± 0.66
Basal Forebrain4.77 ± 0.36
Basal Part of Pons4.99 ± 0.37
Cerebellar Cortex4.31 ± 0.51
Cerebellar Nuclei4.58 ± 0.45
Claustrum4.54 ± 0.99
Epithalamus3.83 ± 0.71
Frontal Lobe4.43 ± 0.55
Globus Pallidus3.85 ± 0.6
Hypothalamus4.25 ± 0.81
Insula4.14 ± 0.61
Limbic Lobe4.73 ± 0.49
Mesencephalon4.47 ± 0.64
Myelencephalon4.49 ± 0.63
Occipital Lobe4.89 ± 0.47
Parietal Lobe4.74 ± 0.48
Pontine Tegmentum4.59 ± 0.6
Striatum5.25 ± 0.32
Subthalamus4.74 ± 0.12
Temporal Lobe4.57 ± 0.53
Thalamus4.29 ± 0.61
White Matter3.54 ± 0.5
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Abcc5CBCerebellum17.32
19.73
Abcc5CTXCerebral cortex59.28
39.67
Abcc5HIPHippocampal region33.31
31
Abcc5HPFHippocampal formation38.62
32.3
Abcc5HYHypothalamus21.04
15.61
Abcc5LSXLateral septal complex28.25
19.25
Abcc5MBMidbrain23.73
18.27
Abcc5MYMedulla31.46
28.05
Abcc5OLFOlfactory bulb48.91
35.37
Abcc5PPons26.07
22.29
Abcc5PALPallidum30.71
25.44
Abcc5RHPRetrohippocampal region47.41
34.2
Abcc5sAMYStriatum-like amygdalar nuclei43.21
27.22
Abcc5STRStriatum38.71
25.43
Abcc5STRdStriatum dorsal region36.52
24.46
Abcc5STRvStriatum ventral region45.47
27.7
Abcc5THThalamus52.11
38.99
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018