AutismKB 2.0

Annotation Detail for DPP3


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Basic Information Top
Gene Symbol:DPP3 ( DPPIII,FLJ11387,FLJ22331 )
Gene Full Name: dipeptidyl-peptidase 3
Band: 11q13.2
Quick LinksEntrez ID:10072; OMIM: 606818; Uniprot ID:DPP3_HUMAN; ENSEMBL ID: ENSG00000174483; HGNC ID: 3008
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst11 / 62319176
fetus59 / 564012104
neonate4 / 31097128
infant1 / 2362042
juvenile11 / 55556197
adult184 / 193912194
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor10 / 94178106
cervical tumor3 / 3436687
chondrosarcoma3 / 8282336
colorectal tumor8 / 11424670
esophageal tumor3 / 17290173
gastrointestinal tumor17 / 119369142
germ cell tumor69 / 263845261
glioma16 / 106883149
head and neck tumor46 / 136302337
kidney tumor7 / 68959101
leukemia15 / 95842156
liver tumor7 / 9635972
lung tumor16 / 103127155
lymphoma11 / 71755153
non-neoplasia4 / 9725041
normal315 / 336030793
ovarian tumor8 / 76682104
pancreatic tumor11 / 104616105
primitive neuroectodermal tumor of the CNS29 / 125680230
prostate cancer11 / 102680107
retinoblastoma5 / 46356107
skin tumor7 / 12494956
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites5 / 40015124
bladder4 / 29757134
blood14 / 123478113
bone4 / 7165555
bone marrow9 / 48801184
brain155 / 1100989140
cervix11 / 48171228
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue29 / 215722134
esophagus3 / 20209148
eye20 / 21105494
heart3 / 8962633
intestine24 / 234472102
kidney27 / 211777127
larynx0 / 241450 
liver10 / 20774348
lung32 / 33697494
lymph5 / 44270112
lymph node9 / 9161098
mammary gland17 / 153271110
mouth45 / 67052671
muscle0 / 1077150 
nerve2 / 15768126
ovary9 / 10205188
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta18 / 28082564
prostate20 / 189345105
salivary gland0 / 201550 
skin22 / 210574104
spleen14 / 53952259
stomach9 / 9661993
testis32 / 33044296
thymus8 / 8113198
thyroid1 / 4747321
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord1 / 1368073
uterus21 / 23287890
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218567_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts131.05
Adipocyte5.9
AdrenalCortex5.25
Adrenalgland4.3
Amygdala5.1
Appendix5.15
AtrioventricularNode3.8
BDCA4+_DentriticCells50.95
Bonemarrow6.2
BronchialEpithelialCells36.5
CD105+_Endothelial30.35
CD14+_Monocytes12.05
CD19+_BCells(neg._sel.)5.7
CD33+_Myeloid22.7
CD34+25.75
CD4+_Tcells8.25
CD56+_NKCells24.45
CD71+_EarlyErythroid6.4
CD8+_Tcells5.9
CardiacMyocytes6.6
Caudatenucleus4.3
Cerebellum4.05
CerebellumPeduncles5.6
CiliaryGanglion3.5
CingulateCortex5.15
Colorectaladenocarcinoma28.3
DorsalRootGanglion3.75
FetalThyroid4.9
Fetalbrain5.95
Fetalliver4.45
Fetallung4.4
GlobusPallidus3.7
Heart6.45
Hypothalamus5.55
Kidney4.1
Leukemia_chronicMyelogenousK-5626.7
Leukemia_promyelocytic-HL-6020.2
Leukemialymphoblastic(MOLT-4)19.05
Liver10.05
Lung6.8
Lymphnode4.4
Lymphoma_burkitts(Daudi)6.55
Lymphoma_burkitts(Raji)16.95
MedullaOblongata4.55
OccipitalLobe4.4
OlfactoryBulb3.8
Ovary3.3
Pancreas4.1
PancreaticIslet5.5
ParietalLobe5.3
Pituitary5.85
Placenta5.3
Pons4.75
PrefrontalCortex6.05
Prostate6
Salivarygland4.05
SkeletalMuscle5.7
Skin3.85
SmoothMuscle15.45
Spinalcord5.5
SubthalamicNucleus4.45
SuperiorCervicalGanglion6
TemporalLobe4.65
Testis4.45
TestisGermCell4.05
TestisIntersitial3.95
TestisLeydigCell5
TestisSeminiferousTubule4.2
Thalamus5.15
Thymus4.3
Thyroid6.2
Tongue4.95
Tonsil5
Trachea4.25
TrigeminalGanglion5.05
Uterus3.8
UterusCorpus4.45
WholeBlood7.55
Wholebrain4.55
colon5.15
pineal_day8.2
pineal_night6.32
retina6.1
small_intestine5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7888_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.71 ± 0.87
Basal Forebrain2.95 ± 0.39
Basal Part of Pons2.82 ± 0.88
Cerebellar Cortex2.44 ± 0.54
Cerebellar Nuclei2.84 ± 0.61
Claustrum3.09 ± 0.82
Epithalamus2.65 ± 0.38
Frontal Lobe2.83 ± 0.66
Globus Pallidus3.73 ± 0.38
Hypothalamus2.69 ± 0.67
Insula2.44 ± 0.71
Limbic Lobe2.83 ± 0.69
Mesencephalon2.78 ± 0.77
Myelencephalon2.83 ± 0.74
Occipital Lobe2.85 ± 0.7
Parietal Lobe2.85 ± 0.72
Pontine Tegmentum2.95 ± 0.62
Striatum3.32 ± 0.57
Subthalamus2.58 ± 0.31
Temporal Lobe2.72 ± 0.73
Thalamus3.18 ± 0.53
White Matter3.5 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dpp3CBCerebellum15.31
27.31
Dpp3CTXCerebral cortex52.24
42.28
Dpp3HIPHippocampal region11.54
12.02
Dpp3HPFHippocampal formation10.54
10.7
Dpp3HYHypothalamus3.97
4.46
Dpp3LSXLateral septal complex3.96
3.07
Dpp3MBMidbrain5.74
8.3
Dpp3MYMedulla8.09
10.63
Dpp3OLFOlfactory bulb37.37
34.2
Dpp3PPons6.24
9.01
Dpp3PALPallidum6.24
6.55
Dpp3RHPRetrohippocampal region8.74
8.77
Dpp3sAMYStriatum-like amygdalar nuclei3.54
3.29
Dpp3STRStriatum6.11
4.73
Dpp3STRdStriatum dorsal region3.78
3.04
Dpp3STRvStriatum ventral region15.3
10.41
Dpp3THThalamus4.56
4.38
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
DPP3_HUMAN_0 0 0 0 GEFEGFVAVVNK PRIDE
DPP3_HUMAN_125 16 125 140 VILGSEAAQQHPEEVR PRIDE
DPP3_HUMAN_2 19 2 20 ADTQYILPNDIGVSSLDCR PRIDE
DPP3_HUMAN_202 13 202 214 EVDGEGKPYYEVR PRIDE
DPP3_HUMAN_548 17 548 564 AGLLALEFYTPEAFNWR PRIDE
DPP3_HUMAN_577 25 577 601 VLLEAGEGLVTITPTTGSDGRPDAR PRIDE
PAp00000579 21 639 659 ALYEGYATVTDAPPECFLTLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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