AutismKB 2.0

Annotation Detail for CDH11


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:CDH11 ( CAD11,CDHOB,OB,OSF-4 )
Gene Full Name: cadherin 11, type 2, OB-cadherin (osteoblast)
Band: 16q21
Quick LinksEntrez ID:1009; OMIM: 600023; Uniprot ID:CAD11_HUMAN; ENSEMBL ID: ENSG00000140937; HGNC ID: 1750
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body14 / 70761197
blastocyst4 / 6231964
fetus89 / 564012157
neonate9 / 31097289
infant0 / 236200 
juvenile4 / 5555671
adult137 / 193912170
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor10 / 94178106
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor11 / 11424696
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor22 / 26384583
glioma6 / 10688356
head and neck tumor24 / 136302176
kidney tumor4 / 6895958
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia20 / 97250205
normal323 / 336030796
ovarian tumor6 / 7668278
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone13 / 71655181
bone marrow2 / 4880140
brain122 / 1100989110
cervix1 / 4817120
connective tissue32 / 149255214
ear8 / 16212493
embryonic tissue23 / 215722106
esophagus1 / 2020949
eye12 / 21105456
heart3 / 8962633
intestine13 / 23447255
kidney21 / 21177799
larynx16 / 24145662
liver2 / 2077439
lung7 / 33697420
lymph0 / 442700 
lymph node0 / 916100 
mammary gland12 / 15327178
mouth8 / 67052119
muscle6 / 10771555
nerve2 / 15768126
ovary7 / 10205168
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta43 / 280825153
prostate1 / 1893455
salivary gland0 / 201550 
skin23 / 210574109
spleen14 / 53952259
stomach2 / 9661920
testis31 / 33044293
thymus2 / 8113124
thyroid0 / 474730 
tonsil0 / 169990 
trachea18 / 52413343
umbilical cord0 / 136800 
uterus46 / 232878197
vascular8 / 51780154
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207172_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.05
Adipocyte70.95
AdrenalCortex16.6
Adrenalgland15.5
Amygdala17.55
Appendix11.1
AtrioventricularNode21.65
BDCA4+_DentriticCells8.55
Bonemarrow12.15
BronchialEpithelialCells12.25
CD105+_Endothelial9.55
CD14+_Monocytes9.65
CD19+_BCells(neg._sel.)9.75
CD33+_Myeloid10.25
CD34+10.7
CD4+_Tcells8.6
CD56+_NKCells9.8
CD71+_EarlyErythroid8.1
CD8+_Tcells7.2
CardiacMyocytes82.15
Caudatenucleus12.95
Cerebellum14.85
CerebellumPeduncles18.2
CiliaryGanglion12.9
CingulateCortex19.3
Colorectaladenocarcinoma10.25
DorsalRootGanglion11.7
FetalThyroid10.15
Fetalbrain12.6
Fetalliver9.8
Fetallung20.45
GlobusPallidus10.7
Heart14.75
Hypothalamus17.65
Kidney10.35
Leukemia_chronicMyelogenousK-5629.1
Leukemia_promyelocytic-HL-609.35
Leukemialymphoblastic(MOLT-4)8.2
Liver15.1
Lung16.55
Lymphnode12.85
Lymphoma_burkitts(Daudi)13.8
Lymphoma_burkitts(Raji)15.1
MedullaOblongata12.55
OccipitalLobe12.55
OlfactoryBulb8.8
Ovary17.55
Pancreas8.4
PancreaticIslet10.5
ParietalLobe14.7
Pituitary17.75
Placenta18.35
Pons14.3
PrefrontalCortex11.95
Prostate13.25
Salivarygland9.05
SkeletalMuscle19.2
Skin8.6
SmoothMuscle206.05
Spinalcord16.75
SubthalamicNucleus10.05
SuperiorCervicalGanglion29
TemporalLobe11.2
Testis9.05
TestisGermCell8.95
TestisIntersitial8.95
TestisLeydigCell12.9
TestisSeminiferousTubule9.75
Thalamus13.45
Thymus7.35
Thyroid13.45
Tongue12.05
Tonsil12.45
Trachea19.65
TrigeminalGanglion15.7
Uterus33.7
UterusCorpus10.1
WholeBlood11.5
Wholebrain15.95
colon10.25
pineal_day10.74
pineal_night10.86
retina20.775
small_intestine10.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14984_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.48 ± 0.49
Basal Forebrain4.75 ± 0.47
Basal Part of Pons4.8 ± 0.51
Cerebellar Cortex4.3 ± 0.29
Cerebellar Nuclei4.38 ± 0.54
Claustrum4.64 ± 0.7
Epithalamus4.85 ± 0.52
Frontal Lobe4.86 ± 0.41
Globus Pallidus5.18 ± 0.29
Hypothalamus4.49 ± 0.59
Insula4.75 ± 0.41
Limbic Lobe5.05 ± 0.44
Mesencephalon4.7 ± 0.59
Myelencephalon4.71 ± 0.56
Occipital Lobe4.61 ± 0.57
Parietal Lobe4.56 ± 0.49
Pontine Tegmentum4.7 ± 0.5
Striatum5.66 ± 0.38
Subthalamus4.51 ± 0.34
Temporal Lobe4.57 ± 0.41
Thalamus4.65 ± 0.55
White Matter4.56 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cdh11CBCerebellum6.89
11.79
Cdh11CTXCerebral cortex34.67
29.93
Cdh11HIPHippocampal region45.01
58.81
Cdh11HPFHippocampal formation41.62
51.24
Cdh11HYHypothalamus3.15
2.77
Cdh11LSXLateral septal complex30.88
28.77
Cdh11MBMidbrain4.1
5.74
Cdh11MYMedulla2.36
3.28
Cdh11OLFOlfactory bulb8.7
8.08
Cdh11PPons3.11
3.76
Cdh11PALPallidum4.15
3.96
Cdh11RHPRetrohippocampal region36.95
35.51
Cdh11sAMYStriatum-like amygdalar nuclei2.28
2.52
Cdh11STRStriatum10.21
8.96
Cdh11STRdStriatum dorsal region7.52
6.76
Cdh11STRvStriatum ventral region15.85
12.04
Cdh11THThalamus7.33
7.61
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved