AutismKB 2.0

Annotation Detail for TSPAN5


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Basic Information Top
Gene Symbol:TSPAN5 ( NET-4,NET4,TM4SF9,TSPAN-5 )
Gene Full Name: tetraspanin 5
Band: 4q23
Quick LinksEntrez ID:10098; OMIM: 613136; Uniprot ID:TSN5_HUMAN; ENSEMBL ID: ENSG00000168785; HGNC ID: 17753
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst0 / 623190 
fetus84 / 564012148
neonate1 / 3109732
infant4 / 23620169
juvenile1 / 5555617
adult105 / 193912154
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma15 / 82823181
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor21 / 26384579
glioma14 / 106883130
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor9 / 9635993
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal436 / 3360307129
ovarian tumor6 / 7668278
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone11 / 71655153
bone marrow1 / 4880120
brain100 / 110098990
cervix0 / 481710 
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus0 / 202090 
eye18 / 21105485
heart7 / 8962678
intestine9 / 23447238
kidney16 / 21177775
larynx0 / 241450 
liver9 / 20774343
lung16 / 33697447
lymph0 / 442700 
lymph node1 / 9161010
mammary gland4 / 15327126
mouth1 / 6705214
muscle3 / 10771527
nerve3 / 15768190
ovary7 / 10205168
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta8 / 28082528
prostate5 / 18934526
salivary gland0 / 201550 
skin198 / 210574940
spleen0 / 539520 
stomach1 / 9661910
testis19 / 33044257
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus8 / 23287834
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209890_at
Cell line Expression level Expression bar
721_B_lymphoblasts12.9
Adipocyte14.5
AdrenalCortex22.4
Adrenalgland11.65
Amygdala87.3
Appendix15.3
AtrioventricularNode24.25
BDCA4+_DentriticCells10.5
Bonemarrow88.75
BronchialEpithelialCells106.85
CD105+_Endothelial64.85
CD14+_Monocytes13.1
CD19+_BCells(neg._sel.)17.5
CD33+_Myeloid11.95
CD34+16.25
CD4+_Tcells22.25
CD56+_NKCells20.75
CD71+_EarlyErythroid838.85
CD8+_Tcells14.75
CardiacMyocytes29.6
Caudatenucleus16.05
Cerebellum47.3
CerebellumPeduncles93.45
CiliaryGanglion12.75
CingulateCortex62.15
Colorectaladenocarcinoma33.45
DorsalRootGanglion13.3
FetalThyroid22.75
Fetalbrain64.85
Fetalliver26.55
Fetallung21.35
GlobusPallidus34.9
Heart23.45
Hypothalamus29.5
Kidney13.6
Leukemia_chronicMyelogenousK-56213.15
Leukemia_promyelocytic-HL-609.05
Leukemialymphoblastic(MOLT-4)23.85
Liver25.75
Lung25.6
Lymphnode12.25
Lymphoma_burkitts(Daudi)18.65
Lymphoma_burkitts(Raji)21.05
MedullaOblongata34.9
OccipitalLobe53.6
OlfactoryBulb21
Ovary12.1
Pancreas14.15
PancreaticIslet17.15
ParietalLobe75.35
Pituitary16.65
Placenta13.65
Pons24.2
PrefrontalCortex40.8
Prostate24.15
Salivarygland13.05
SkeletalMuscle25.8
Skin17.6
SmoothMuscle22.5
Spinalcord19.1
SubthalamicNucleus51.65
SuperiorCervicalGanglion27.25
TemporalLobe47.1
Testis15.45
TestisGermCell17.4
TestisIntersitial16.8
TestisLeydigCell17.4
TestisSeminiferousTubule15.3
Thalamus17
Thymus13.25
Thyroid28.15
Tongue21.05
Tonsil18.55
Trachea12.9
TrigeminalGanglion24
Uterus37.75
UterusCorpus15.4
WholeBlood15.6
Wholebrain218.6
colon10.1
pineal_day132.48
pineal_night132.38
retina26.175
small_intestine9.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P153937
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.93 ± 0.45
Basal Forebrain3.2 ± 0.41
Basal Part of Pons3.74 ± 0.73
Cerebellar Cortex4 ± 0.41
Cerebellar Nuclei3.42 ± 0.4
Claustrum3.46 ± 0.73
Epithalamus3.31 ± 0.61
Frontal Lobe3.55 ± 0.66
Globus Pallidus3.25 ± 0.41
Hypothalamus3.17 ± 0.57
Insula3.67 ± 0.45
Limbic Lobe3.95 ± 0.53
Mesencephalon3.46 ± 0.67
Myelencephalon3.63 ± 0.66
Occipital Lobe4.02 ± 0.46
Parietal Lobe3.64 ± 0.62
Pontine Tegmentum3.63 ± 0.55
Striatum3.14 ± 0.67
Subthalamus3.81 ± 0.75
Temporal Lobe3.66 ± 0.56
Thalamus3.47 ± 0.62
White Matter3.58 ± 0.31
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tspan5CBCerebellum37.34
89.93
Tspan5CTXCerebral cortex100
100
Tspan5HIPHippocampal region100
100
Tspan5HPFHippocampal formation100
100
Tspan5HYHypothalamus10.75
9.63
Tspan5LSXLateral septal complex44.88
42.09
Tspan5MBMidbrain32.14
36.29
Tspan5MYMedulla31.62
46.15
Tspan5OLFOlfactory bulb98.59
100
Tspan5PPons30.91
45.66
Tspan5PALPallidum33.05
41.14
Tspan5RHPRetrohippocampal region100
100
Tspan5sAMYStriatum-like amygdalar nuclei41.06
37.83
Tspan5STRStriatum57.6
54.21
Tspan5STRdStriatum dorsal region61.25
56.42
Tspan5STRvStriatum ventral region61.06
61.56
Tspan5THThalamus57.77
60.26
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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