AutismKB 2.0

Annotation Detail for NUBP2


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Basic Information Top
Gene Symbol:NUBP2 ( CFD1,NUBP1 )
Gene Full Name: nucleotide binding protein 2 (MinD homolog, E. coli)
Band: 16p13.3
Quick LinksEntrez ID:10101; OMIM: 610779; Uniprot ID:NUBP2_HUMAN; ENSEMBL ID: ENSG00000095906; HGNC ID: 8042
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst3 / 6231948
fetus15 / 56401226
neonate1 / 3109732
infant3 / 23620127
juvenile3 / 5555653
adult86 / 193912144
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor13 / 94178138
cervical tumor4 / 34366116
chondrosarcoma5 / 8282360
colorectal tumor9 / 11424678
esophageal tumor2 / 17290115
gastrointestinal tumor3 / 11936925
germ cell tumor5 / 26384518
glioma13 / 106883121
head and neck tumor6 / 13630244
kidney tumor9 / 68959130
leukemia8 / 9584283
liver tumor6 / 9635962
lung tumor16 / 103127155
lymphoma3 / 7175541
non-neoplasia4 / 9725041
normal141 / 336030741
ovarian tumor16 / 76682208
pancreatic tumor18 / 104616172
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer9 / 10268087
retinoblastoma7 / 46356151
skin tumor19 / 124949152
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor5 / 9025755
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland1 / 3319730
ascites2 / 4001549
bladder1 / 2975733
blood17 / 123478137
bone9 / 71655125
bone marrow0 / 488010 
brain45 / 110098940
cervix6 / 48171124
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue20 / 21572292
esophagus2 / 2020998
eye16 / 21105475
heart1 / 8962611
intestine17 / 23447272
kidney11 / 21177751
larynx0 / 241450 
liver8 / 20774338
lung21 / 33697462
lymph3 / 4427067
lymph node3 / 9161032
mammary gland15 / 15327197
mouth0 / 670520 
muscle7 / 10771564
nerve2 / 15768126
ovary19 / 102051186
pancreas19 / 21481288
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta8 / 28082528
prostate17 / 18934589
salivary gland6 / 20155297
skin22 / 210574104
spleen3 / 5395255
stomach3 / 9661931
testis0 / 3304420 
thymus9 / 81131110
thyroid0 / 474730 
tonsil2 / 16999117
trachea1 / 5241319
umbilical cord1 / 1368073
uterus11 / 23287847
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7371_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.62 ± 0.4
Basal Forebrain5.47 ± 0.25
Basal Part of Pons5.65 ± 0.4
Cerebellar Cortex5.79 ± 0.39
Cerebellar Nuclei5.53 ± 0.32
Claustrum5.65 ± 0.31
Epithalamus5.31 ± 0.4
Frontal Lobe5.64 ± 0.39
Globus Pallidus5.68 ± 0.52
Hypothalamus5.63 ± 0.57
Insula5.56 ± 0.34
Limbic Lobe5.53 ± 0.38
Mesencephalon5.6 ± 0.46
Myelencephalon5.58 ± 0.39
Occipital Lobe5.23 ± 0.32
Parietal Lobe5.55 ± 0.31
Pontine Tegmentum5.51 ± 0.35
Striatum5.3 ± 0.25
Subthalamus5.13 ± 0.36
Temporal Lobe5.61 ± 0.38
Thalamus5.56 ± 0.34
White Matter5.84 ± 0.32
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nubp2CBCerebellum8.97
16.4
Nubp2CTXCerebral cortex8.43
6.51
Nubp2HIPHippocampal region4.39
4.72
Nubp2HPFHippocampal formation3.03
3.18
Nubp2HYHypothalamus3.03
3.43
Nubp2LSXLateral septal complex0.9
0.68
Nubp2MBMidbrain3.89
4.28
Nubp2MYMedulla2.24
3.18
Nubp2OLFOlfactory bulb3.32
4.2
Nubp2PPons2.84
5.04
Nubp2PALPallidum1.11
1.63
Nubp2RHPRetrohippocampal region0.52
0.84
Nubp2sAMYStriatum-like amygdalar nuclei0.07
0.04
Nubp2STRStriatum0.38
0.35
Nubp2STRdStriatum dorsal region0.3
0.38
Nubp2STRvStriatum ventral region0.52
0.31
Nubp2THThalamus2.03
1.77
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NUBP2_HUMAN_1 14 1 14 MEAAAEPGNLAGVR PRIDE
NUBP2_HUMAN_234 27 234 260 TLEEGHDFIQEFPGSPAFAALTSIAQK PRIDE
PAp00079042 27 235 261 TLEEGHDFIQEFPGSPAFAALTSIAQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018