AutismKB 2.0

Annotation Detail for TRAP1


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Basic Information Top
Gene Symbol:TRAP1 ( HSP75,HSP90L )
Gene Full Name: TNF receptor-associated protein 1
Band: 16p13.3
Quick LinksEntrez ID:10131; OMIM: 606219; Uniprot ID:TRAP1_HUMAN; ENSEMBL ID: ENSG00000126602; HGNC ID: 16264
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst8 / 62319128
fetus59 / 564012104
neonate5 / 31097160
infant6 / 23620254
juvenile32 / 55556575
adult307 / 1939121158
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor13 / 94178138
cervical tumor17 / 34366494
chondrosarcoma12 / 82823144
colorectal tumor36 / 114246315
esophageal tumor6 / 17290347
gastrointestinal tumor41 / 119369343
germ cell tumor88 / 263845333
glioma41 / 106883383
head and neck tumor24 / 136302176
kidney tumor23 / 68959333
leukemia22 / 95842229
liver tumor21 / 96359217
lung tumor58 / 103127562
lymphoma66 / 71755919
non-neoplasia7 / 9725071
normal468 / 3360307139
ovarian tumor18 / 76682234
pancreatic tumor25 / 104616238
primitive neuroectodermal tumor of the CNS69 / 125680549
prostate cancer20 / 102680194
retinoblastoma43 / 46356927
skin tumor67 / 124949536
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor21 / 90257232
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland7 / 33197210
ascites17 / 40015424
bladder3 / 29757100
blood26 / 123478210
bone9 / 71655125
bone marrow10 / 48801204
brain298 / 1100989270
cervix19 / 48171394
connective tissue13 / 14925587
ear1 / 1621261
embryonic tissue25 / 215722115
esophagus6 / 20209296
eye63 / 211054298
heart14 / 89626156
intestine54 / 234472230
kidney46 / 211777217
larynx1 / 2414541
liver26 / 207743125
lung75 / 336974222
lymph61 / 442701377
lymph node4 / 9161043
mammary gland21 / 153271137
mouth18 / 67052268
muscle11 / 107715102
nerve1 / 1576863
ovary25 / 102051244
pancreas35 / 214812162
parathyroid0 / 205390 
pharynx7 / 41328169
pituitary gland1 / 1658560
placenta37 / 280825131
prostate35 / 189345184
salivary gland1 / 2015549
skin75 / 210574356
spleen14 / 53952259
stomach22 / 96619227
testis74 / 330442223
thymus18 / 81131221
thyroid7 / 47473147
tonsil2 / 16999117
trachea7 / 52413133
umbilical cord1 / 1368073
uterus34 / 232878145
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201391_at
Cell line Expression level Expression bar
721_B_lymphoblasts601.4
Adipocyte170.9
AdrenalCortex175.05
Adrenalgland134.65
Amygdala195.45
Appendix163.85
AtrioventricularNode127.7
BDCA4+_DentriticCells181.5
Bonemarrow168.35
BronchialEpithelialCells331.3
CD105+_Endothelial419.3
CD14+_Monocytes166.45
CD19+_BCells(neg._sel.)186.35
CD33+_Myeloid188.55
CD34+413.15
CD4+_Tcells288.25
CD56+_NKCells208.95
CD71+_EarlyErythroid161.65
CD8+_Tcells224.95
CardiacMyocytes205.1
Caudatenucleus155
Cerebellum138.95
CerebellumPeduncles207
CiliaryGanglion118.3
CingulateCortex195.8
Colorectaladenocarcinoma318.45
DorsalRootGanglion129.2
FetalThyroid168.05
Fetalbrain198.2
Fetalliver155.8
Fetallung158.75
GlobusPallidus124.45
Heart334.5
Hypothalamus193.7
Kidney137.9
Leukemia_chronicMyelogenousK-562550.1
Leukemia_promyelocytic-HL-60354.45
Leukemialymphoblastic(MOLT-4)171.15
Liver467.8
Lung195.65
Lymphnode151.45
Lymphoma_burkitts(Daudi)546.4
Lymphoma_burkitts(Raji)658.1
MedullaOblongata158.85
OccipitalLobe158.3
OlfactoryBulb136.75
Ovary92.15
Pancreas147.8
PancreaticIslet191.4
ParietalLobe187.5
Pituitary201.8
Placenta102.55
Pons171.6
PrefrontalCortex194.4
Prostate239.3
Salivarygland115.15
SkeletalMuscle234.4
Skin129.8
SmoothMuscle181.35
Spinalcord184.65
SubthalamicNucleus155.2
SuperiorCervicalGanglion170.85
TemporalLobe158.8
Testis209.5
TestisGermCell146.7
TestisIntersitial145.65
TestisLeydigCell157.8
TestisSeminiferousTubule150.25
Thalamus191.25
Thymus138.45
Thyroid221.1
Tongue175.1
Tonsil161.05
Trachea119.25
TrigeminalGanglion139.4
Uterus153
UterusCorpus141.75
WholeBlood72.65
Wholebrain264.35
colon171.8
pineal_day182.58
pineal_night164.88
retina163.175
small_intestine153.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_17123_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.96 ± 0.62
Basal Forebrain4.89 ± 0.5
Basal Part of Pons5.53 ± 0.43
Cerebellar Cortex5.27 ± 0.47
Cerebellar Nuclei4.9 ± 0.36
Claustrum4.61 ± 1.01
Epithalamus5.07 ± 0.53
Frontal Lobe5.3 ± 0.45
Globus Pallidus4.77 ± 0.44
Hypothalamus5.33 ± 0.37
Insula5.37 ± 0.42
Limbic Lobe5.17 ± 0.53
Mesencephalon5.1 ± 0.63
Myelencephalon5.11 ± 0.51
Occipital Lobe4.8 ± 0.46
Parietal Lobe5.19 ± 0.51
Pontine Tegmentum5.13 ± 0.49
Striatum5 ± 0.5
Subthalamus5.19 ± 0.34
Temporal Lobe5.32 ± 0.42
Thalamus5.15 ± 0.4
White Matter4.62 ± 0.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Trap1CBCerebellum45.39
67.58
Trap1CTXCerebral cortex80.1
67.34
Trap1HIPHippocampal region69.05
73.57
Trap1HPFHippocampal formation84.79
77.06
Trap1HYHypothalamus70.09
39.12
Trap1LSXLateral septal complex54.22
23.93
Trap1MBMidbrain71.41
52.94
Trap1MYMedulla81.66
75.01
Trap1OLFOlfactory bulb93.11
65.46
Trap1PPons76.84
64.86
Trap1PALPallidum71.47
48.96
Trap1RHPRetrohippocampal region93.71
83.7
Trap1sAMYStriatum-like amygdalar nuclei72.04
38.21
Trap1STRStriatum63.51
30.82
Trap1STRdStriatum dorsal region57.61
27.52
Trap1STRvStriatum ventral region74.21
40.17
Trap1THThalamus72.64
63.37
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003182 14 389 402 GVVDSEDIPLNLSR Peptide Atlas
TRAP1_HUMAN_0 0 0 0 GVVDSEDIPLNLSR PRIDE
TRAP1_HUMAN_131 21 131 151 LVSDGQALPEMEIHLQTNAEK PRIDE
TRAP1_HUMAN_181 15 181 195 AFLDALQNQAEASSK PRIDE
TRAP1_HUMAN_340 17 340 356 SIFYVPDMKPSMFDVSR PRIDE
TRAP1_HUMAN_341 17 341 357 SIFYVPDMKPSMFDVSR PRIDE
TRAP1_HUMAN_357 11 357 367 ELGSSVALYSR PRIDE
TRAP1_HUMAN_388 14 388 401 GVVDSEDIPLNLSR PRIDE
TRAP1_HUMAN_389 14 389 402 GVVDSEDIPLNLSR PRIDE
TRAP1_HUMAN_402 10 402 411 ELLQESALIR PRIDE
TRAP1_HUMAN_439 10 439 448 FFEDYGLFMR PRIDE
TRAP1_HUMAN_440 10 440 449 FFEDYGLFMR PRIDE
TRAP1_HUMAN_449 17 449 465 EGIVTATEQEVKEDIAK PRIDE
TRAP1_HUMAN_506 13 506 518 HLAEHSPYYEAMK PRIDE
TRAP1_HUMAN_634 13 634 646 AQLLQPTLEINPR PRIDE
TRAP1_HUMAN_649 10 649 658 ALIKKLNQLR PRIDE
TRAP1_HUMAN_658 29 658 686 ASEPGLAQLLVDQIYENAMIAAGLVDDPR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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